A new multivariate count data model to study multi-category physician prescription behavior

Multivariate count models represent a natural way of accommodating data from multiple product categories when the dependent variable in each category is represented by a positive integer. In this paper, we propose a new simultaneous equation multi-category count data model–the Poisson-lognormal simultaneous equation model–that allows for the Poisson parameter in one equation to be a function of the Poisson parameters in other equations. While generally applicable to any situation where simultaneity is an issue and the dependent variables are measured as counts, such a specification is particularly useful for our empirical application where physicians prescribe drugs in multiple categories. Accounting for the endogeneity of detailing in such situations requires us to explicitly allow for pharmaceutical firms’ detailing activities in one category to be influenced by their activities in other categories. Estimation of such a system of equations using traditional maximum likelihood method is cumbersome, so we propose a simple solution based on using Markov Chain Monte Carlo methods. Our simulation study demonstrates the validity of the solution algorithm and the biases that would result if such simultaneity is ignored in the estimation process.We apply our methodology to study multi-category physician prescription behavior, while accounting for the endogeneity and simultaneity of firms’ detailing efforts within and across categories, at individual physician level. Substantively, we show that detailing responsiveness estimates, as well as their implications for physician segmentation and firms’ profits are significantly affected when we leverage data from multiple categories to account for endogeneity in detailing decisions.

[1]  D. Wittink,et al.  Competitive Reaction versus Consumer response: Do Managers Overreact? , 1996 .

[2]  Sunil Gupta,et al.  The Shopping Basket: A Model for Multicategory Purchase Incidence Decisions , 1999 .

[3]  Puneet Manchanda,et al.  Quantifying the Benefits of Individual-Level Targeting in the Presence of Firm Strategic Behavior , 2009 .

[4]  Pravin K. Trivedi,et al.  Regression Analysis of Count Data , 1998 .

[5]  Shantanu Dutta,et al.  Physicians' Persistence and its Implications for Their Response to Promotion of Prescription Drugs , 2008, Manag. Sci..

[6]  Dani Gamerman,et al.  Markov Chain Monte Carlo: Stochastic Simulation for Bayesian Inference , 1997 .

[7]  Chakravarthi Narasimhan,et al.  Modeling Dependencies in Brand Choice Outcomes Across Complementary Categories , 2012 .

[8]  Sönke Albers,et al.  Personal Selling Elasticities: A Meta-Analysis , 2010 .

[9]  Peter E. Rossi,et al.  Response Modeling with Nonrandom Marketing-Mix Variables , 2004 .

[10]  A. Zoltners,et al.  Sales-Force Decision Models: Insights from 25 Years of Implementation , 2001 .

[11]  J. Aitchison,et al.  The multivariate Poisson-log normal distribution , 1989 .

[12]  Adrian F. M. Smith,et al.  Sampling-Based Approaches to Calculating Marginal Densities , 1990 .

[13]  G. King,et al.  A Seemingly Unrelated Poisson Regression Model , 1989 .

[14]  Gary J. Russell,et al.  Perspectives on Multiple Category Choice , 1997 .

[15]  Tülin Erdem,et al.  An Empirical Investigation of the Spillover Effects of Advertising and Sales Promotions in Umbrella Branding , 2002 .

[16]  Invited Commentary---Commentary on Structural Modeling in Marketing: Review and Assessment , 2006 .

[17]  D. Wittink,et al.  Diagnosing competitive reactions using (aggregated) scanner data , 1992 .

[18]  Sunil Gupta,et al.  Allocating Marketing Resources , 2008 .

[19]  Harikesh S. Nair,et al.  Intertemporal price discrimination with forward-looking consumers: Application to the US market for console video-games , 2006 .

[20]  Murat K. Munkin,et al.  Simulated maximum likelihood estimation of multivariate mixed‐Poisson regression models, with application , 1999 .

[21]  Gary J. Russell,et al.  Multiple-Category Decision-Making: Review and Synthesis , 1999 .

[22]  Invited Commentary---Comment on Structural Modeling in Marketing: Review and Assessment , 2006 .

[23]  Donald Geman,et al.  Stochastic Relaxation, Gibbs Distributions, and the Bayesian Restoration of Images , 1984, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[24]  Achim Wambach,et al.  Incentive effects in the demand for health care: a bivariate panel count data estimation , 2003 .

[25]  S. E. Hills,et al.  Illustration of Bayesian Inference in Normal Data Models Using Gibbs Sampling , 1990 .

[26]  Peter E. Rossi,et al.  NBER WORKING PAPER SERIES STATE DEPENDENCE AND ALTERNATIVE EXPLANATIONS FOR CONSUMER INERTIA , 2009 .

[27]  Peter E. Rossi,et al.  Structural Modeling in Marketing: Review and Assessment , 2004 .

[28]  Peter E. Rossi,et al.  Similarities in Choice Behavior Across Product Categories , 1998 .

[29]  N. L. Johnson,et al.  Discrete Multivariate Distributions , 1998 .

[30]  I. Wiklund,et al.  Psychosocial factors and their role in symptomatic gastroesophageal reflux disease and functional dyspepsia. , 1996, Scandinavian journal of gastroenterology. Supplement.

[31]  Tülin Erdem An Empirical Analysis of Umbrella Branding , 1998 .

[32]  Hui-ming Wang,et al.  A Bayesian multivariate Poisson regression model of cross-category store brand purchasing behavior , 2007 .

[33]  S. Chib,et al.  Models of Multi-Category Choice Behavior , 2005 .

[34]  M. Wallander,et al.  Severe gastro‐oesophageal reflux symptoms in relation to anxiety, depression and coping in a population‐based study , 2007, Alimentary pharmacology & therapeutics.

[35]  Shibo Li,et al.  Modeling Category Viewership of Web Users with Multivariate Count Models , 2002 .

[36]  Peter E. Rossi,et al.  Bayesian Statistics and Marketing , 2005 .

[37]  Geert Wets,et al.  Using association rules for product assortment decisions: a case study , 1999, KDD '99.

[38]  M. Wosinska,et al.  Just What the Patient Ordered? Direct-to-Consumer Advertising and the Demand for Pharmaceutical Products , 2002 .

[39]  S. Kocherlakota,et al.  Bivariate discrete distributions , 1992 .

[40]  Eugenio J. Miravete Multivariate Sarmanov Count Data Models , 2009 .

[41]  B. Avidan,et al.  Reflux symptoms are associated with psychiatric disease , 2001, Alimentary pharmacology & therapeutics.

[42]  Pradeep K. Chintagunta,et al.  Understanding Store-Brand Purchase Behavior Across Categories , 2006 .

[43]  S. Chib,et al.  Analysis of multi-category purchase incidence decisions using IRI market basket data , 2002 .

[44]  W. Wong,et al.  The calculation of posterior distributions by data augmentation , 1987 .

[45]  Pradeep Chintagunta,et al.  Measuring Cross-Category Price Effects with Aggregate Store Data , 2006, Manag. Sci..

[46]  Steven T. Berry,et al.  Automobile Prices in Market Equilibrium , 1995 .

[47]  David M. Zimmer,et al.  Modelling the Differences in Counted Outcomes Using Bivariate Copula Models with Application to Mismeasured Counts , 2004 .

[48]  Füsun F. Gönül,et al.  Promotion of Prescription Drugs and Its Impact on Physicians' Choice Behavior , 2001 .

[49]  Wagner A. Kamakura,et al.  Inferring Market Structure from Customer Response to Competing and Complementary Products , 2001 .