Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: Relevance to Alzheimer's disease

[1]  D. Butterfield,et al.  Proteomic identification of proteins oxidized by Aβ(1–42) in synaptosomes: Implications for Alzheimer's disease , 2005, Brain Research.

[2]  D. Butterfield,et al.  Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. , 2002, Free radical biology & medicine.

[3]  Martin H Maurer,et al.  Comparison of statistical approaches for the analysis of proteome expression data of differentiating neural stem cells. , 2005, Journal of proteome research.

[4]  D. Butterfield,et al.  Ferulic acid ethyl ester protects neurons against amyloid β‐ peptide(1–42)‐induced oxidative stress and neurotoxicity: relationship to antioxidant activity , 2005, Journal of neurochemistry.

[5]  D. Allan Butterfield,et al.  Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: Insights into the development of Alzheimer's disease , 2006, Neurobiology of Disease.

[6]  W. Jakoby,et al.  Glutathione S-transferases (rat and human). , 1981, Methods in enzymology.

[7]  James I. Garrels,et al.  Annotating the human proteome: the Human Proteome Survey Database (HumanPSDTM) and an in-depth target database for G protein-coupled receptors (GPCR-PDTM) from Incyte Genomics , 2002, Nucleic Acids Res..

[8]  D. Butterfield Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain , 2004, Brain Research.

[9]  K. Fritz-Wolf,et al.  Functional aspects of the X-ray structure of mitochondrial creatine kinase: A molecular physiology approach , 1998, Molecular and Cellular Biochemistry.

[10]  P. Bickford,et al.  Caloric restriction prevents age-related deficits in LTP and in NMDA receptor expression. , 2000, Brain research. Molecular brain research.

[11]  P. Mecocci,et al.  Oxidative damage to mitochondrial DNA shows marked age‐dependent increases in human brain , 1993, Annals of neurology.

[12]  Visith Thongboonkerd,et al.  Proteomic identification of nitrated proteins in Alzheimer's disease brain , 2003, Journal of neurochemistry.

[13]  D. Butterfield,et al.  Acetylcarnitine and cellular stress response: roles in nutritional redox homeostasis and regulation of longevity genes. , 2006, The Journal of nutritional biochemistry.

[14]  G. Stark,et al.  Free radical induced inactivation of creatine kinase: sites of interaction, protection, and recovery. , 2000, Biochimica et biophysica acta.

[15]  D. Butterfield,et al.  The critical role of methionine 35 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity. , 2005, Biochimica et biophysica acta.

[16]  Norton W. Milgram,et al.  Development of a protocol for studying object recognition memory in the dog , 2000, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[17]  D. Allan Butterfield,et al.  Acrolein inhibits NADH-linked mitochondrial enzyme activity: Implications for Alzheimer's disease , 2009, Neurotoxicity Research.

[18]  D. Butterfield,et al.  Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1--42) and A beta(25--35). , 2001, Journal of the American Chemical Society.

[19]  C. Cotman,et al.  Visuospatial function in the beagle dog: An early marker of cognitive decline in a model of human aging and dementia , 2006, Neurobiology of Learning and Memory.

[20]  Josephine C. Adams,et al.  Roles of fascin in cell adhesion and motility. , 2004, Current opinion in cell biology.

[21]  D. Butterfield,et al.  The antioxidants α‐lipoic acid and N‐acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice , 2003, Journal of neurochemistry.

[22]  F. Gage,et al.  Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus , 1999, Nature Neuroscience.

[23]  R. Dixon,et al.  Use it or lose it: engaged lifestyle as a buffer of cognitive decline in aging? , 1999, Psychology and aging.

[24]  A. Chakrabartty,et al.  Oxidation-induced Misfolding and Aggregation of Superoxide Dismutase and Its Implications for Amyotrophic Lateral Sclerosis* , 2002, The Journal of Biological Chemistry.

[25]  D. Butterfield,et al.  Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid β-peptide (1–42) into rat brain: Implications for Alzheimer’s disease , 2005, Neuroscience.

[26]  P. Bickford,et al.  Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats , 2000, Brain Research.

[27]  C. Cotman,et al.  Magnetic resonance imaging of anatomic and vascular characteristics in a canine model of human aging , 1998, Neurobiology of Aging.

[28]  D. Butterfield,et al.  Proteomic analysis of brain proteins in the gracile axonal dystrophy (gad) mouse, a syndrome that emanates from dysfunctional ubiquitin carboxyl‐terminal hydrolase L‐1, reveals oxidation of key proteins , 2004, Journal of neurochemistry.

[29]  D. Butterfield,et al.  Antisense directed at the Aβ region of APP decreases brain oxidative markers in aged senescence accelerated mice , 2004, Brain Research.

[30]  D. Allan Butterfield,et al.  Mitochondrial associated metabolic proteins are selectively oxidized in A30P α-synuclein transgenic mice—a model of familial Parkinson's disease , 2005, Neurobiology of Disease.

[31]  D. Greene,et al.  Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy. , 2000, Diabetes.

[32]  D. Butterfield,et al.  Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase‐related protein 2, α‐enolase and heat shock cognate 71 , 2002, Journal of neurochemistry.

[33]  W. D. Ehmann,et al.  Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease , 1995, Neurology.

[34]  C. Cotman,et al.  Visuospatial impairments in aged canines (Canis familiaris): the role of cognitive-behavioral flexibility. , 2002, Behavioral neuroscience.

[35]  D. Butterfield,et al.  The glial glutamate transporter, GLT‐1, is oxidatively modified by 4‐hydroxy‐2‐nonenal in the Alzheimer's disease brain: the role of Aβ1–42 , 2001, Journal of neurochemistry.

[36]  D. Butterfield,et al.  Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis. , 2005, Free radical biology & medicine.

[37]  B. Wu,et al.  Expression of heat shock protein 70 is altered by age and diet at the level of transcription , 1993, Molecular and cellular biology.

[38]  D. Butterfield,et al.  Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain , 2004, Neuroscience.

[39]  D. Butterfield,et al.  Amyloid beta-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists. , 2002, Journal of Alzheimer's disease : JAD.

[40]  C. Cotman,et al.  Visual-discrimination learning ability and β-amyloid accumulation in the dog , 1998, Neurobiology of Aging.

[41]  S. Srivastava,et al.  Membrane Association of Glutathione S-Transferase mGSTA4-4, an Enzyme That Metabolizes Lipid Peroxidation Products* , 2002, The Journal of Biological Chemistry.

[42]  D. Tappa,et al.  Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification : a two-year longitudinal study , 2004 .

[43]  D. Butterfield,et al.  Antisense directed at the Abeta region of APP decreases brain oxidative markers in aged senescence accelerated mice. , 2004, Brain research.

[44]  D. Allan Butterfield,et al.  Chapter 7 Protein Oxidation Processes in Aging Brain , 1997 .

[45]  S. Little,et al.  Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis. , 1991, Brain research. Molecular brain research.

[46]  C. Cotman,et al.  Region-specific age at onset of beta-amyloid in dogs. , 2000, Neurobiology of aging.

[47]  Min-Ying Su,et al.  Application of an automated voxel-based morphometry technique to assess regional gray and white matter brain atrophy in a canine model of aging , 2006, NeuroImage.

[48]  M. Mattson,et al.  Reactive Oxygen Species as Causal Agents in the Neurotoxicity of the Alzheimer's Disease‐Associated Amyloid Beta Peptide a , 1996, Annals of the New York Academy of Sciences.

[49]  J. Valentine,et al.  Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis. , 2005, Annual review of biochemistry.

[50]  M. Somerville,et al.  Neurofilament Light and Polyadenylated mRNA Levels Are Decreased in Amyotrophic Lateral Sclerosis Motor Neurons , 1994, Journal of neuropathology and experimental neurology.

[51]  Josephine C. Adams,et al.  Fascin protrusions in cell interactions. , 2004, Trends in cardiovascular medicine.

[52]  A. Sawa,et al.  GAPDH as a sensor of NO stress. , 2006, Biochimica et biophysica acta.

[53]  C. Cotman,et al.  Long-term treatment with antioxidants and a program of behavioral enrichment reduces age-dependent impairment in discrimination and reversal learning in beagle dogs , 2004, Experimental Gerontology.

[54]  D. Chuang,et al.  Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases. , 2005, Annual review of pharmacology and toxicology.

[55]  P. Bickford,et al.  Long-Term Dietary Strawberry, Spinach, or Vitamin E Supplementation Retards the Onset of Age-Related Neuronal Signal-Transduction and Cognitive Behavioral Deficits , 1998, The Journal of Neuroscience.

[56]  B. Wu,et al.  The effect of age on the synthesis of two heat shock proteins in the hsp70 family. , 1993, Journal of gerontology.

[57]  C. Cotman,et al.  Frontal lobe volume, function, and beta-amyloid pathology in a canine model of aging - eScholarship , 2004 .

[58]  D. Butterfield,et al.  Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach , 2006, Neurobiology of Disease.

[59]  V. Calabrese,et al.  Vitamin E and Neurodegenerative Disorders Associated with Oxidative Stress , 2002, Nutritional neuroscience.

[60]  D. Butterfield,et al.  Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide. , 2001, Trends in molecular medicine.

[61]  D. Butterfield,et al.  Elevation of mitochondrial glutathione by γ‐glutamylcysteine ethyl ester protects mitochondria against peroxynitrite‐induced oxidative stress , 2003, Journal of neuroscience research.

[62]  D. Butterfield,et al.  Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer's disease. , 2003, The Italian journal of biochemistry.

[63]  T. Getchell,et al.  Proteomic identification of differentially expressed proteins in the aging murine olfactory system and transcriptional analysis of the associated genes , 2005, Journal of neurochemistry.

[64]  Brian J Cummings,et al.  β-Amyloid Accumulation Correlates with Cognitive Dysfunction in the Aged Canine , 1996, Neurobiology of Learning and Memory.

[65]  Victoria M Perreau,et al.  Voluntary Exercise Decreases Amyloid Load in a Transgenic Model of Alzheimer's Disease , 2005, The Journal of Neuroscience.

[66]  W. Jakoby,et al.  [27] Glutathione S-transferases (rat and human) , 1981 .

[67]  N. Cairns,et al.  Neurofilament proteins NF-L, NF-M and NF-H in brain of patients with Down syndrome and Alzheimer's disease , 2001, Amino Acids.

[68]  D. Butterfield,et al.  Amyloid β‐Peptide(1‐42) Contributes to the Oxidative Stress and Neurodegeneration Found in Alzheimer Disease Brain , 2004, Brain pathology.

[69]  C. Cotman,et al.  Landmark discrimination learning in the dog. , 1999, Learning & memory.

[70]  J. Lindsay,et al.  Physical activity and risk of cognitive impairment and dementia in elderly persons. , 2001, Archives of neurology.

[71]  D. Butterfield,et al.  Protein oxidation and enzyme activity decline in old brown Norway rats are reduced by dietary restriction , 1998, Mechanisms of Ageing and Development.

[72]  B. Ames,et al.  Oxidative damage increases with age in a canine model of human brain aging , 2002, Journal of neurochemistry.

[73]  D. Butterfield,et al.  Proteomic analysis of specific brain proteins in aged SAMP8 mice treated with alpha-lipoic acid: implications for aging and age-related neurodegenerative disorders , 2005, Neurochemistry International.

[74]  C. Cotman,et al.  Region-specific age at onset of β-amyloid in dogs☆ , 2000, Neurobiology of Aging.

[75]  A. Wu,et al.  Automated assay of oxygen radical absorbance capacity with the COBAS FARA II. , 1995, Clinical chemistry.

[76]  W. Markesbery,et al.  Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[77]  T. Getchell,et al.  Quantitative proteomics analysis of differential protein expression and oxidative modification of specific proteins in the brains of old mice , 2006, Neurobiology of Aging.

[78]  Vladimir V. Frolkis,et al.  Neurobiology of Aging , 2019, Psychobiology of Behaviour.

[79]  Brian J Cummings,et al.  The canine as an animal model of human aging and dementia , 1996, Neurobiology of Aging.

[80]  M. Mattson,et al.  A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[81]  I. Fridovich,et al.  Copper- and Zinc-containing Superoxide Dismutase Can Act as a Superoxide Reductase and a Superoxide Oxidase* , 2000, The Journal of Biological Chemistry.

[82]  J. Trojanowski,et al.  Oxidation of Cytosolic Proteins and Expression of Creatine Kinase BB in Frontal Lobe in Different Neurodegenerative Disorders , 1999, Dementia and Geriatric Cognitive Disorders.

[83]  W. Markesbery,et al.  Increased DNA Oxidation and Decreased Levels of Repair Products in Alzheimer's Disease Ventricular CSF , 1999, Journal of neurochemistry.

[84]  C Xie,et al.  Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease , 1998, Neurology.

[85]  Kai Chen,et al.  Neurons Overexpressing Heme Oxygenase‐1 Resist Oxidative Stress‐Mediated Cell Death , 2000, Journal of neurochemistry.

[86]  P. Bickford,et al.  Age-related neurodegeneration and oxidative stress: putative nutritional intervention. , 1998, Neurologic clinics.

[87]  D. Allan Butterfield,et al.  Proteomic Analysis of Protein Expression and Oxidative Modification in R6/2 Transgenic Mice , 2005, Molecular & Cellular Proteomics.

[88]  Brian J Cummings,et al.  β-Amyloid accumulation in aged canine brain: A model of early plaque formation in Alzheimer's disease , 1993, Neurobiology of Aging.

[89]  C. Cotman,et al.  Dietary enrichment counteracts age-associated cognitive dysfunction in canines , 2002, Neurobiology of Aging.

[90]  J. Valentine Do oxidatively modified proteins cause ALS? , 2002, Free radical biology & medicine.

[91]  R. Tyrrell Redox regulation and oxidant activation of heme oxygenase-1. , 1999, Free radical research.

[92]  D. Butterfield,et al.  Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis. , 2005, Free radical biology & medicine.

[93]  D. Butterfield,et al.  Redox regulation in neurodegeneration and longevity: role of the heme oxygenase and HSP70 systems in brain stress tolerance. , 2004, Antioxidants & redox signaling.

[94]  Visith Thongboonkerd,et al.  Proteomic analysis of normal human urinary proteins isolated by acetone precipitation or ultracentrifugation. , 2002, Kidney international.

[95]  R. W. Gracy,et al.  Identification of protein carbonyls after two‐dimensional electrophoresis , 2001, Proteomics.

[96]  B. Halliwell,et al.  Free Radicals and Antioxidants in the Year 2000: A Historical Look to the Future , 2000, Annals of the New York Academy of Sciences.

[97]  R. Perham The fructose-1,6-bisphosphate aldolases: same reaction, different enzymes. , 1990, Biochemical Society transactions.

[98]  S. Barnes,et al.  Superoxide Dismutase Catalyzes Nitration of Tyrosines by Peroxynitrite in the Rod and Head Domains of Neurofilament‐L , 1997, Journal of neurochemistry.

[99]  S. Snyder,et al.  Amyloid Precursor Proteins Inhibit Heme Oxygenase Activity and Augment Neurotoxicity in Alzheimer's Disease , 2000, Neuron.

[100]  C. Cotman,et al.  Brain aging in the canine: a diet enriched in antioxidants reduces cognitive dysfunction , 2002, Neurobiology of Aging.

[101]  D. Butterfield,et al.  Oxidative Modification of Creatine Kinase BB in Alzheimer’s Disease Brain , 2000, Journal of neurochemistry.

[102]  D. Butterfield,et al.  Proteomics analysis provides insight into caloric restriction mediated oxidation and expression of brain proteins associated with age-related impaired cellular processes: Mitochondrial dysfunction, glutamate dysregulation and impaired protein synthesis , 2006, Neurobiology of Aging.

[103]  D. Butterfield,et al.  Lipid peroxidation and protein oxidation in Alzheimer's disease brain: Potential causes and consequences involving amyloid β-peptide-associated free radical oxidative stress , 2002 .

[104]  D. Allan Butterfield,et al.  Brain protein oxidation in age-related neurodegenerative disorders that are associated with aggregated proteins , 2001, Mechanisms of Ageing and Development.

[105]  D. Butterfield,et al.  Proteomics in Alzheimer's disease: insights into potential mechanisms of neurodegeneration , 2003, Journal of neurochemistry.

[106]  D. Butterfield,et al.  Brain Regional Correspondence Between Alzheimer's Disease Histopathology and Biomarkers of Protein Oxidation , 1995, Journal of neurochemistry.

[107]  D. Butterfield,et al.  Increased expression of heat shock proteins in rat brain during aging: relationship with mitochondrial function and glutathione redox state , 2004, Mechanisms of Ageing and Development.

[108]  T. Hornemann,et al.  Some new aspects of creatine kinase (CK): compartmentation, structure, function and regulation for cellular and mitochondrial bioenergetics and physiology , 1998, BioFactors.

[109]  D. Butterfield,et al.  Amyloid beta-peptide (1-40)-mediated oxidative stress in cultured hippocampal neurons. Protein carbonyl formation, CK BB expression, and the level of Cu, Zn, and Mn SOD mRNA. , 1998, Journal of molecular neuroscience : MN.

[110]  E. Head,et al.  Insights into Aβ and Presenilin from a Canine Model of Human Brain Aging , 2002, Neurobiology of Disease.

[111]  D. Price,et al.  Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease. , 1987, Science.

[112]  L. Ji Exercise‐induced Modulation of Antioxidant Defense , 2002, Annals of the New York Academy of Sciences.

[113]  D. Butterfield,et al.  γ‐Glutamylcysteine ethyl ester protection of proteins from Aβ(1–42)‐mediated oxidative stress in neuronal cell culture: A proteomics approach , 2005, Journal of neuroscience research.

[114]  T. Wallimann,et al.  Mitochondrial Creatine Kinase Is a Prime Target of Peroxynitrite-induced Modification and Inactivation* , 1998, The Journal of Biological Chemistry.

[115]  C. Cotman,et al.  Visual-discrimination learning ability and beta-amyloid accumulation in the dog. , 1998, Neurobiology of aging.

[116]  D. Bennett,et al.  Vitamin E and donepezil for the treatment of mild cognitive impairment. , 2005, The New England journal of medicine.

[117]  Josephine C. Adams,et al.  Fascins, and their roles in cell structure and function. , 2002, BioEssays : news and reviews in molecular, cellular and developmental biology.

[118]  J W Griffin,et al.  Neurofilament gene expression: a major determinant of axonal caliber. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[119]  C. Cotman,et al.  Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging. , 2003, Learning & memory.

[120]  T. Woolsey,et al.  Restricted neuronal expression of ubiquitous mitochondrial creatine kinase: Changing patterns in development and with increased activity , 2003, Molecular and Cellular Biochemistry.

[121]  D. Butterfield,et al.  Oxidatively Modified GST and MRP1 in Alzheimer’s Disease Brain: Implications for Accumulation of Reactive Lipid Peroxidation Products , 2004, Neurochemical Research.