Real-time quantitative terahertz microfluidic sensing based on photonic crystal pillar array

The microfluidic sensing based on the photonic crystal (PC) pillar array was investigated in the terahertz (THz) region. We fabricated the silicon PC sensors, and experimentally and theoretically demonstrated their resonances by using the THz time-domain spectroscopy system. According to the corresponding changes of the resonances dependent on the different microfluidics on the PC sensor, the qualitative monitoring can be achieved. By establishing the relation between the experimental data and simulations, the amount of microfluidic at each moment on the different PC sensors can be exactly determined. These PC sensors have great promising potential in the real-time quantitative sensing.

[1]  Ja-Yu Lu,et al.  Terahertz refractive index sensors using dielectric pipe waveguides. , 2012, Optics express.

[2]  P. Siegel.  Terahertz technology in biology and medicine , 2004, 2004 IEEE MTT-S International Microwave Symposium Digest (IEEE Cat. No.04CH37535).

[3]  Li Wang,et al.  Modulated terahertz responses of split ring resonators by nanometer thick liquid layers , 2008 .

[4]  David S. Citrin,et al.  Photonic crystals for biochemical sensing in the terahertz region , 2005 .

[5]  Daniel M. Mittleman,et al.  Dependence of guided resonances on the structural parameters of terahertz photonic crystal slabs , 2008 .

[6]  D. Mittleman,et al.  Terahertz microfluidic sensor based on a parallel-plate waveguide resonant cavity , 2009 .

[7]  S Hayashi,et al.  Terahertz surface-wave resonant sensor with a metal hole array. , 2006, Optics letters.

[8]  Derek Abbott,et al.  Label-free bioaffinity detection using terahertz technology. , 2002, Physics in medicine and biology.

[9]  Li Wang,et al.  Label-free monitoring of interaction between DNA and oxaliplatin in aqueous solution by terahertz spectroscopy , 2012 .

[10]  Peter Uhd Jepsen,et al.  Investigation of aqueous alcohol and sugar solutions with reflection terahertz time-domain spectroscopy. , 2007, Optics express.

[11]  J Li,et al.  Distinguishing octane grades in gasoline using terahertz metamaterials. , 2012, Applied optics.

[12]  Fei Fan,et al.  Terahertz modulator based on insulator-metal transition in photonic crystal waveguide. , 2012, Applied optics.

[13]  Kodo Kawase,et al.  Terahertz sensing method for protein detection using a thin metallic mesh , 2007 .

[14]  G. Bastiaans,et al.  Absorption coefficients of selected explosives and related compounds in the range of 0.1-2.8 THz. , 2007, Optics express.

[15]  Cunlin Zhang,et al.  Out-of-plane resonances in terahertz photonic crystal slabs modulated by optical pumping. , 2011, Optics express.

[16]  Daniel M. Mittleman,et al.  Terahertz multichannel microfluidic sensor based on parallel-plate waveguide resonant cavities , 2011, 2011 International Conference on Infrared, Millimeter, and Terahertz Waves.

[17]  D. Grischkowsky,et al.  Terahertz demonstrations of effectively two-dimensional photonic bandgap structures. , 2006, Optics letters.