Neuromodulation system in closed loop for enhancing the sleep and the memory consolidation

Recently, there has been growing interest in analyzing the relationship between sleep quality and brain capacities, in terms of memory consolidation and the possible appearance of degenerative diseases such as dementias, including Alzheimer. This paper presents the development of the neuromodulation closed-loop algorithms for sleep stages, spindles and slow-wave sleep (SWS) detection and stimulation generation based on a single electroencephalography (EEG) signal acquisition with the aim of developing a wearable device easy to wear and easy to use for the users. This work presents the characteristics of the system and the initial results.

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