The effect of injected solutions on the cell content of the cerebrospinal fluid.

An account has been given in an earlier paper (Bedford, 1946) of the effect of the introduction of isotonic sodium chloride solution into the cisterna magna on the cell content of the cerebrospinal fluid of dogs anaesthetized with "nembutal " (Abbott). The duration of these experiments was approximately five hours. Polymorphonuclear leucocytes, generally unaccom- panied by other reactive cells, were present at the end of nine out of thirteen experiments. The introduction under did not cause reactive changes and after time by solutions of procaine, amylocaine, and amethocaine hydrochlorides. effect the introduction solution.