H2Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain

[1]  Y. Satoh,et al.  Molecular Hydrogen Attenuates Neuropathic Pain in Mice , 2014, PloS one.

[2]  Y. de Koninck,et al.  Enhancing K-Cl co-transport restores normal spinothalamic sensory coding in a neuropathic pain model. , 2014, Brain : a journal of neurology.

[3]  R. Chen,et al.  Gabapentin Enhances the Morphine Anti-Nociceptive Effect in Neuropathic Pain via the Interleukin-10-Heme Oxygenase-1 Signalling Pathway in Rats , 2014, Journal of Molecular Neuroscience.

[4]  GuoLin Wang,et al.  Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages. , 2013, International journal of surgery.

[5]  John H. Zhang,et al.  Hydrogen-Rich Saline Attenuated Neuropathic Pain by Reducing Oxidative Stress , 2013, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[6]  Nirmal Singh,et al.  Neuropathic pain-attenuating potential of aliskiren in chronic constriction injury model in rats , 2013, Journal of the renin-angiotensin-aldosterone system : JRAAS.

[7]  R. Motterlini,et al.  Treatment with Carbon Monoxide-releasing Molecules and an HO-1 Inducer Enhances the Effects and Expression of µ-Opioid Receptors during Neuropathic Pain , 2013, Anesthesiology.

[8]  G. Geisslinger,et al.  Modulation of central nervous system–specific microRNA-124a alters the inflammatory response in the formalin test in mice , 2013, PAIN®.

[9]  P. Sacerdote,et al.  Cytokine Modulation is Necessary for Efficacious Treatment of Experimental Neuropathic Pain , 2013, Journal of Neuroimmune Pharmacology.

[10]  Ailin Li,et al.  Combination Therapy With Molecular Hydrogen and Hyperoxia in a Murine Model of Polymicrobial Sepsis , 2012, Shock.

[11]  Nirmal Singh,et al.  Neuroprotective effect of saponin rich extract of Acorus calamus L. in rat model of chronic constriction injury (CCI) of sciatic nerve-induced neuropathic pain. , 2012, Journal of ethnopharmacology.

[12]  S. Winch,et al.  Autonomy versus futility? Barriers to good clinical practice in end‐of‐life care: a Queensland case , 2012, The Medical journal of Australia.

[13]  S. V. Padi,et al.  Pharmacological activation of heme oxygenase (HO)-1/carbon monoxide pathway prevents the development of peripheral neuropathic pain in Wistar rats , 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

[14]  GuoLin Wang,et al.  Role of TRPM8 in dorsal root ganglion in nerve injury-induced chronic pain , 2011, BMC Neuroscience.

[15]  R. Dong,et al.  Effects of clonidine on bilateral pain behaviors and inflammatory response in rats under the state of neuropathic pain , 2011, Neuroscience Letters.

[16]  M. Hutchinson,et al.  Peripheral immune contributions to the maintenance of central glial activation underlying neuropathic pain , 2011, Brain, Behavior, and Immunity.

[17]  J. P. de Rivero Vaccari,et al.  Functional Recovery after Peripheral Nerve Injury is Dependent on the Pro-Inflammatory Cytokines IL-1β and TNF: Implications for Neuropathic Pain , 2011, The Journal of Neuroscience.

[18]  G. F. Passos,et al.  Activation of cannabinoid receptors by the pentacyclic triterpene α,β-amyrin inhibits inflammatory and neuropathic persistent pain in mice , 2011, PAIN®.

[19]  W. Fan,et al.  Carbon monoxide: A gas that modulates nociception , 2011, Journal of neuroscience research.

[20]  K. Tracey,et al.  HMGB1 is a therapeutic target for sterile inflammation and infection. , 2011, Annual review of immunology.

[21]  Nirmal Singh,et al.  Differential effect of spironolactone in chronic constriction injury and vincristine-induced neuropathic pain in rats. , 2010, European journal of pharmacology.

[22]  GuoLin Wang,et al.  Hydrogen Gas Improves Survival Rate and Organ Damage in Zymosan-Induced Generalized Inflammation Model , 2010, Shock.

[23]  GuoLin Wang,et al.  PROTECTIVE EFFECTS OF HYDROGEN GAS ON MURINE POLYMICROBIAL SEPSIS VIA REDUCING OXIDATIVE STRESS AND HMGB1 RELEASE , 2010, Shock.

[24]  F. Amaya,et al.  Induction of high mobility group box-1 in dorsal root ganglion contributes to pain hypersensitivity after peripheral nerve injury , 2010, PAIN.

[25]  M. Alcaraz,et al.  The CO-releasing molecule CORM-3 protects against articular degradation in the K/BxN serum transfer arthritis model. , 2010, European journal of pharmacology.

[26]  Sheng-Xi Wu,et al.  Spinal high-mobility group box 1 contributes to mechanical allodynia in a rat model of bone cancer pain. , 2010, Biochemical and biophysical research communications.

[27]  A. Cuadrado,et al.  Haeme oxygenase-1 overexpression via nAChRs and the transcription factor Nrf2 has antinociceptive effects in the formalin test , 2009, PAIN.

[28]  M. Alcaraz,et al.  The CO-releasing molecule CORM-2 is a novel regulator of the inflammatory process in osteoarthritic chondrocytes. , 2008, Rheumatology.

[29]  K. Kimura,et al.  Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury. , 2008, Biochemical and biophysical research communications.

[30]  A. I. Rojo,et al.  Nrf2-mediated haeme oxygenase-1 up-regulation induced by cobalt protoporphyrin has antinociceptive effects against inflammatory pain in the formalin test in mice , 2008, PAIN®.

[31]  R. Ji,et al.  Cytokine Mechanisms of Central Sensitization: Distinct and Overlapping Role of Interleukin-1β, Interleukin-6, and Tumor Necrosis Factor-α in Regulating Synaptic and Neuronal Activity in the Superficial Spinal Cord , 2008, The Journal of Neuroscience.

[32]  P. Sacerdote,et al.  Transient early expression of TNF-α in sciatic nerve and dorsal root ganglia in a mouse model of painful peripheral neuropathy , 2008, Neuroscience Letters.

[33]  Aihui Li,et al.  IL-1ra alleviates inflammatory hyperalgesia through preventing phosphorylation of NMDA receptor NR-1 subunit in rats , 2008, PAIN.

[34]  Ping-Heng Tan,et al.  Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain , 2008, Nature Medicine.

[35]  S. Maier,et al.  “Listening” and “talking” to neurons: Implications of immune activation for pain control and increasing the efficacy of opioids , 2007, Brain Research Reviews.

[36]  C. Woolf,et al.  The neuropathic pain triad: neurons, immune cells and glia , 2007, Nature Neuroscience.

[37]  C. Sommer,et al.  Early cytokine expression in mouse sciatic nerve after chronic constriction nerve injury depends on calpain , 2007, Brain, Behavior, and Immunity.

[38]  Yasuo Katayama,et al.  Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals , 2007, Nature Medicine.

[39]  F. Cunha,et al.  Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development? , 2006, Pharmacology & therapeutics.

[40]  T. Olsson,et al.  Cytokine responses during chronic denervation , 2005, Journal of Neuroinflammation.

[41]  M. Avilés-Trigueros,et al.  Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1α and interleukin-1β in Wallerian degeneration , 2005 .

[42]  M. Avilés-Trigueros,et al.  Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1alpha and interleukin-1beta in Wallerian degeneration. , 2005, Brain : a journal of neurology.

[43]  S. Maier,et al.  Spinal Glia and Proinflammatory Cytokines Mediate Mirror-Image Neuropathic Pain in Rats , 2003, The Journal of Neuroscience.

[44]  F. Cunha,et al.  Antinociceptive Effects of Interleukin-4, -10, and -13 on the Writhing Response in Mice and Zymosan-Induced Knee Joint Incapacitation in Rats , 2003, Journal of Pharmacology and Experimental Therapeutics.

[45]  P. Sarathchandra,et al.  Carbon Monoxide-Releasing Molecules: Characterization of Biochemical and Vascular Activities , 2002, Circulation research.

[46]  F. Cunha,et al.  Role of the haeme oxygenase/carbon monoxide pathway in mechanical nociceptor hypersensitivity , 2001, British journal of pharmacology.

[47]  R. Yezierski,et al.  The role of neuroinflammation and neuroimmune activation in persistent pain , 2001, Pain.

[48]  R. Helme,et al.  Free radicals contribute to the reduction in peripheral vascular responses and the maintenance of thermal hyperalgesia in rats with chronic constriction injury , 1999, Pain.

[49]  T. Yaksh,et al.  Quantitative assessment of tactile allodynia in the rat paw , 1994, Journal of Neuroscience Methods.

[50]  P. Ricciardi-Castagnoli,et al.  Central effects of tumor necrosis factor α and interleukin-1α on nociceptive thresholds and spontaneous locomotor activity , 1992, Neuroscience Letters.

[51]  P. Ricciardi-Castagnoli,et al.  Central effects of tumor necrosis factor alpha and interleukin-1 alpha on nociceptive thresholds and spontaneous locomotor activity. , 1992, Neuroscience letters.

[52]  Gary J. Bennett,et al.  A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man , 1988, Pain.