Identification of collagen α1(I) trimer in embryonic chick tendons and calvaria

Abstract Collagen with a molecular composition [ α 1 (I)] 3 has been identified in acetic acid extracts from lathyritic chick embryo tendons and calvaria. These molecules characteristically have greater solubility than Type I collagen at neutral pH and contain increased amounts of hydroxylysine residues. It is suggested that these molecules represent a separate gene product of embryonic cells which may be important in the process of maturation and development.

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