N-Methyl N-Nitrosourea Induced Functional and Structural Alterations in Mice Brain-Role of Curcumin

[1]  A. Hoffman,et al.  Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[2]  C. Tirolo,et al.  Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease , 2010, Journal of Neuroinflammation.

[3]  S. Ponzoni,et al.  Manganese neurotoxic time course is not influenced by l-deprenyl systemic treatment Influence of l-deprenyl in manganese neurotoxic time course , 2010, Brain Research.

[4]  R. Chandra,et al.  Attenuation of arsenic neurotoxicity by curcumin in rats. , 2009, Toxicology and applied pharmacology.

[5]  J. Brender,et al.  Determining the effects of lipophilic drugs on membrane structure by solid-state NMR spectroscopy: the case of the antioxidant curcumin. , 2009, Journal of the American Chemical Society.

[6]  S. Kulkarni,et al.  Anti-depressant like effect of curcumin and its combination with piperine in unpredictable chronic stress-induced behavioral, biochemical and neurochemical changes , 2009, Pharmacology Biochemistry and Behavior.

[7]  K. Hayakawa,et al.  Decreased acetylcholine release is correlated to memory impairment in the Tg2576 transgenic mouse model of Alzheimer's disease , 2009, Brain Research.

[8]  M. Yousef,et al.  Ameliorating effect of curcumin on sodium arsenite-induced oxidative damage and lipid peroxidation in different rat organs. , 2009, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[9]  S. Okada,et al.  Curcumin attenuates oxidative damage in animals treated with a renal carcinogen, ferric nitrilotriacetate (Fe-NTA): implications for cancer prevention , 2009, Molecular and Cellular Biochemistry.

[10]  W. Ohyama,et al.  Detection of micronucleated cells and gene expression changes in glandular stomach of mice treated with stomach-targeted carcinogens. , 2008, Mutation research.

[11]  P. Perjési,et al.  Early modification of c-myc, Ha-ras and p53 expressions by N-methyl-N-nitrosourea. , 2008, In vivo.

[12]  K. Huse,et al.  Curcumin Inhibits Glyoxalase 1—A Possible Link to Its Anti-Inflammatory and Anti-Tumor Activity , 2008, PloS one.

[13]  J. Zhao,et al.  Neuroprotective effect of curcumin on transient focal cerebral ischemia in rats , 2008, Brain Research.

[14]  P. Shukla,et al.  Anti-ischemic Effect of Curcumin in Rat Brain , 2008, Neurochemical Research.

[15]  A. Shilkaitis,et al.  Short-term Modulation of Cell Proliferation and Apoptosis and Preventive/Therapeutic Efficacy of Various Agents in a Mammary Cancer Model , 2007, Clinical Cancer Research.

[16]  Helgi I. Ingólfsson,et al.  Curcumin is a modulator of bilayer material properties. , 2007, Biochemistry.

[17]  P. Mukherjee,et al.  Curcumin-phospholipid complex: Preparation, therapeutic evaluation and pharmacokinetic study in rats. , 2007, International journal of pharmaceutics.

[18]  K. Chopra,et al.  Involvement of adenosinergic receptor system in an animal model of tardive dyskinesia and associated behavioural, biochemical and neurochemical changes. , 2006, European journal of pharmacology.

[19]  Anil Kumar,et al.  Neuroprotective Effects of Resveratrol against Intracerebroventricular Colchicine-Induced Cognitive Impairment and Oxidative Stress in Rats , 2006, Pharmacology.

[20]  B. Tripathy,et al.  Neuroprotective and Anti-ageing Effects of Curcumin in Aged Rat Brain Regions , 2006, Biogerontology.

[21]  M. Mayford,et al.  A mutant mouse with a highly specific contextual fear-conditioning deficit found in an N-ethyl-N-nitrosourea (ENU) mutagenesis screen. , 2006, Learning & memory.

[22]  K. Chopra,et al.  Curcumin, a diferuloylmethane, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys , 2005, BMC pharmacology.

[23]  Xue-jun Li,et al.  Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats , 2005, Pharmacology Biochemistry and Behavior.

[24]  M. Suckow,et al.  Susceptibility of Lobund–Wistar × Copenhagen hybrid rats to autochthonous prostate carcinogenesis , 2005, The Prostate.

[25]  H. Arafa.  Curcumin attenuates diet-induced hypercholesterolemia in rats. , 2005, Medical Science Monitor.

[26]  C. Devi,et al.  Developmental lead exposure alters mitochondrial monoamine oxidase and synaptosomal catecholamine levels in rat brain , 2005, International Journal of Developmental Neuroscience.

[27]  Amitava Das,et al.  Role of molecular isoforms of acetylcholinesterase in learning and memory functions , 2005, Pharmacology Biochemistry and Behavior.

[28]  Fusheng Yang,et al.  Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo* , 2005, Journal of Biological Chemistry.

[29]  K. Srinivasan,et al.  Influence of dietary spices on the fluidity of erythrocytes in hypercholesterolaemic rats , 2005, British Journal of Nutrition.

[30]  R. Puvanakrishnan,et al.  Curcumin modulates free radical quenching in myocardial ischaemia in rats. , 2004, The international journal of biochemistry & cell biology.

[31]  S. Chaudhuri,et al.  Immunotherapeutic effects of T11TS/S-LFA3 against nitrosocompound mediated neural genotoxicity. , 2004, Toxicology letters.

[32]  S. Raisuddin,et al.  Chemomodulatory Influence of Ferula asafoetida on Mammary Epithelial Differentiation, Hepatic Drug Metabolizing Enzymes, Antioxidant Profiles and N-methyl-N-Nitrosourea-Induced Mammary Carcinogenesis in Rats , 2003, Breast Cancer Research and Treatment.

[33]  M. Müller,et al.  Organotrope carcinogene Wirkungen bei 65 verschiedenen N-Nitroso-Verbindungen an BD-Ratten , 2004, Zeitschrift für Krebsforschung.

[34]  P. Shukla,et al.  Protective effect of curcumin against lead neurotoxicity in rat , 2003, Human & experimental toxicology.

[35]  S. Okada,et al.  Dietary supplementation of curcumin enhances antioxidant and phase II metabolizing enzymes in ddY male mice: possible role in protection against chemical carcinogenesis and toxicity. , 2003, Pharmacology & toxicology.

[36]  F. Shimamoto,et al.  Variable E-cadherin expression in a MNU-induced colon tumor model in rats which exposed with 50 Hz frequency sinusoidal magnetic field. , 2002, The Tohoku journal of experimental medicine.

[37]  W. Mundy,et al.  Age-related changes in reactive oxygen species production in rat brain homogenates. , 2000, Neurotoxicology and teratology.

[38]  M. Bansal,et al.  Department of Biophysics, Panjab University, Chandigarh-160014, India , 2000 .

[39]  S. Weitzman,et al.  Tumorigenic Conversion of a Rat Urothelial Cell Line by Human Polymorphonuclear Leukocytes Activated by Lipopolysaccharide , 1999, Japanese journal of cancer research : Gann.

[40]  Daniel A. Lim,et al.  Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain , 1999, Cell.

[41]  P. Wang,et al.  [Research on the mechanism of the fatty acid composition on the tumorigenic danger induced by chemical tumorigenic material]. , 1999, Wei sheng yan jiu = Journal of hygiene research.

[42]  B. Kaina,et al.  Targeted expression of human O(6)-methylguanine-DNA methyltransferase (MGMT) in transgenic mice protects against tumor initiation in two-stage skin carcinogenesis. , 1996, Cancer research.

[43]  M. Bosland,et al.  Induction of skin and thyroid tumors in male rats by N-methyl-N-nitrosourea after sequential treatment with cyproterone acetate and testosterone propionate: effects of castration, rat strain and time of carcinogen injection. , 1992, Carcinogenesis.

[44]  M. Le Moal,et al.  Mesocorticolimbic dopaminergic network: functional and regulatory roles. , 1991, Physiological reviews.

[45]  K. Yano,et al.  Reactions of ultimate carcinogens with cell membranes: importance of carbamoylation of phosphatidylethanolamine by the carcinogens. , 1988, Carcinogenesis.

[46]  K. L. Yielding,et al.  Late-onset cerebellar degeneration in mice induced transplacentally by methylnitrosourea. , 1987, Teratogenesis, carcinogenesis, and mutagenesis.

[47]  R. Jope,et al.  Cholinergic processes in blood samples from patients with major psychiatric disorders , 1985, Biological Psychiatry.

[48]  B. Mannervik,et al.  [59] Glutathione reductase , 1985 .

[49]  I. Carlberg,et al.  Glutathione reductase. , 1985, Methods in enzymology.

[50]  Bryan Kolb,et al.  Functions of the frontal cortex of the rat: A comparative review , 1984, Brain Research Reviews.

[51]  C. Mitchell,et al.  Neurobehavioral techniques to assess the effects of chemicals on the nervous system. , 1984, Annual review of pharmacology and toxicology.

[52]  B. Ames,et al.  Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay. , 1983, Analytical biochemistry.

[53]  K. L. Yielding,et al.  Focal cerebellar dystrophy caused by transplacental administration of methylnitrosourea , 1982, Brain Research Bulletin.

[54]  Y. Kono.  Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase. , 1978, Archives of biochemistry and biophysics.

[55]  R. Brady,et al.  Biosynthesis and function of gangliosides. , 1976, Science.

[56]  W B Jakoby,et al.  Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. , 1974, The Journal of biological chemistry.

[57]  J. L. Perhach,et al.  A sensitive, rapid and simple method for the simultaneous spectrophotofluorometric determinations of norepinephrine, dopamine, 5‐hydroxytryptamine and 5‐hydroxyindoleacetic acid in discrete areas of brain , 1973, Journal of neurochemistry.

[58]  P. Kleihues,et al.  [Distribution of N-( 14 C) methyl-N-nitrosourea in the rat after its systemic administration]. , 1971, Zeitschrift fur Krebsforschung.

[59]  C. Frings,et al.  A colorimetric method for determination of total serum lipids based on the sulfo-phospho-vanillin reaction. , 1970, American journal of clinical pathology.

[60]  P. Schein.  1-Methyl-1-nitrosourea Depression of Brain Nicotinamide Adenine Dinucleotide in the Production of Neurologic Toxicity , 1969, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[61]  P. Magee,et al.  Nitrosamine-induced carcinogenesis. The alklylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate. , 1968, The Biochemical journal.

[62]  W. Cleland,et al.  A specific and sensitive assay for disulfides. , 1968, The Journal of biological chemistry.

[63]  H. Druckrey,et al.  [Organotropic carcinogenic effects of 65 various N-nitroso- compounds on BD rats]. , 1967, Zeitschrift fur Krebsforschung.

[64]  B. Ames.  ASSAY OF INORGANIC PHOSPHATE, TOTAL PHOSPHATE AND PHOSPHATASE , 1966 .

[65]  L. Ernster,et al.  Evidence for the involvement of iron in the ADP-activated peroxidation of lipids in microsomes and mitochondria. , 1964, Biochemical and biophysical research communications.

[66]  H. Bergmeyer.  Methods of Enzymatic Analysis , 2019 .

[67]  J. Cohen,et al.  AN AMINE OXIDASE IN NORMAL HUMAN SERUM. , 1963, The Journal of laboratory and clinical medicine.

[68]  K. Courtney,et al.  A new and rapid colorimetric determination of acetylcholinesterase activity. , 1961, Biochemical pharmacology.

[69]  L. Warren,et al.  The thiobarbituric acid assay of sialic acids. , 1959, The Journal of biological chemistry.

[70]  G. Ellman,et al.  Tissue sulfhydryl groups. , 1959, Archives of biochemistry and biophysics.

[71]  J. Folch,et al.  A simple method for the isolation and purification of total lipides from animal tissues. , 1957, The Journal of biological chemistry.

[72]  A. Pearse.  Histochemistry: Theoretical and Applied , 1953 .

[73]  B ZAK,et al.  A new method for the direct determination of serum cholesterol. , 1953, The Journal of laboratory and clinical medicine.