Enalapril overcomes chemoresistance and potentiates antitumor efficacy of 5-FU in colorectal cancer by suppressing proliferation, angiogenesis, and NF-κB/STAT3-regulated proteins
暂无分享,去创建一个
Yun Liu | Jianchun Cai | Wenya Li | Yushan Yang | Lulu Ma | Yiyao Zhang | Yiming Xu
[1] A Phase 3 Randomised Controlled Trial to Evaluate Efficacy and Safety of Anaprazole in Patients With Duodenal Ulcers. , 2020, Case Medical Research.
[2] Jiancong Hu,et al. Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells , 2019, Journal of experimental & clinical cancer research : CR.
[3] H. Lenz,et al. MAVERICC, a Randomized, Biomarker-stratified, Phase II Study of mFOLFOX6-Bevacizumab versus FOLFIRI-Bevacizumab as First-line Chemotherapy in Metastatic Colorectal Cancer , 2018, Clinical Cancer Research.
[4] F. Greten,et al. Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion. , 2018, Cancer cell.
[5] Min Liu,et al. DCLK1 promotes epithelial‐mesenchymal transition via the PI3K/Akt/NF‐κB pathway in colorectal cancer , 2018, International journal of cancer.
[6] R. Fu,et al. miR-206 regulates 5-FU resistance by targeting Bcl-2 in colon cancer cells , 2018, OncoTargets and therapy.
[7] M. Karin,et al. NF-κB, inflammation, immunity and cancer: coming of age , 2018, Nature Reviews Immunology.
[8] Robert A. Weinberg,et al. EMT in cancer , 2018, Nature Reviews Cancer.
[9] W. Belloso,et al. Prediction of severe toxicity in adult patients under treatment with 5-fluorouracil: a prospective cohort study , 2017, Anti-cancer drugs.
[10] A. Jemal,et al. Colorectal cancer statistics, 2017 , 2017, CA: a cancer journal for clinicians.
[11] R. Weinberg,et al. EMT, CSCs, and drug resistance: the mechanistic link and clinical implications , 2017, Nature Reviews Clinical Oncology.
[12] Chen Huang,et al. Regulation of EMT by STAT3 in gastrointestinal cancer (Review). , 2017, International journal of oncology.
[13] O. Stoetzer,et al. Prospective, Multicenter Study of 5-Fluorouracil Therapeutic Drug Monitoring in Metastatic Colorectal Cancer Treated in Routine Clinical Practice. , 2016, Clinical colorectal cancer.
[14] B. Driscoll,et al. Sequestration of Vascular Endothelial Growth Factor (VEGF) Induces Late Restrictive Lung Disease , 2016, PloS one.
[15] Trevor Coward,et al. An In-Vitro Study , 2016 .
[16] C. Qian,et al. Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial–mesenchymal transition , 2015, Carcinogenesis.
[17] I. Herr,et al. Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer , 2015, Oncotarget.
[18] R. Amato,et al. Comparative safety profiles of intravitreal bevacizumab, ranibizumab and pegaptanib: the analysis of the WHO database of adverse drug reactions , 2014, European Journal of Clinical Pharmacology.
[19] Ahmad Hosseini,et al. The role of captopril and losartan in prevention and regression of tamoxifen-induced resistance of breast cancer cell line MCF-7: an in vitro study. , 2014, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[20] D. Lodygin,et al. IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis. , 2014, The Journal of clinical investigation.
[21] P. Spallarossa,et al. Enalapril and carvedilol for preventing chemotherapy-induced left ventricular systolic dysfunction. , 2013, Journal of the American College of Cardiology.
[22] Wilfrid Boireau,et al. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth , 2012, Nature Medicine.
[23] J. Hecht,et al. Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): a phase 3 randomised controlled trial. , 2012, The Lancet. Oncology.
[24] N. Petrelli,et al. Primary mFOLFOX6 plus bevacizumab without resection of the primary tumor for patients presenting with surgically unresectable metastatic colon cancer and an intact asymptomatic colon cancer: definitive analysis of NSABP trial C-10. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[25] Li Lin,et al. STAT3 is necessary for proliferation and survival in colon cancer-initiating cells. , 2011, Cancer research.
[26] K. Hemminki,et al. 5-Fluorouracil-based chemotherapy for colorectal cancer and MTHFR/MTRR genotypes. , 2011, British journal of clinical pharmacology.
[27] S. Zimeras,et al. Cardioprotective effect of metoprolol and enalapril in doxorubicin‐treated lymphoma patients: A prospective, parallel‐group, randomized, controlled study with 36‐month follow‐up , 2010, American journal of hematology.
[28] E. Van Cutsem,et al. Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[29] N. Sasahira,et al. Inhibition of renin–angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine , 2010, British Journal of Cancer.
[30] G. Lau,et al. STAT3 implicated in the development of colon cancer: a step closer for targeted therapy? , 2010, Gastroenterology.
[31] M. Loriot,et al. Pharmacogenetic assessment of toxicity and outcome in patients with metastatic colorectal cancer treated with LV5FU2, FOLFOX, and FOLFIRI: FFCD 2000-05. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[32] Joshua M. Stuart,et al. Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NFκB and microRNA network , 2010, Molecular Cancer.
[33] Hong Jiang,et al. CBP knockdown inhibits angiotensin II-induced vascular smooth muscle cells proliferation through downregulating NF-kB transcriptional activity , 2010, Molecular and Cellular Biochemistry.
[34] V. Preedy,et al. Prospective Cohort Study , 2010 .
[35] G. Feldmann,et al. The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer , 2009, Gut.
[36] R. Osieka,et al. Impact of angiotensin I converting enzyme inhibitors and angiotensin II type 1 receptor blockers on survival in patients with advanced non-small-cell lung cancer undergoing first-line platinum-based chemotherapy , 2009, Journal of Cancer Research and Clinical Oncology.
[37] Hua Yu,et al. Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors. , 2009, Cancer cell.
[38] P. Albertsson,et al. Low-dose continuous 5-fluorouracil infusion stimulates VEGF-A-mediated angiogenesis , 2009, Acta oncologica.
[39] J. Marshall. Coming of age. , 2008, Surgical infections.
[40] B. Aggarwal,et al. Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products. , 2007, Cancer research.
[41] Giovanni Martinelli,et al. Prevention of High-Dose Chemotherapy-Induced Cardiotoxicity in High-Risk Patients by Angiotensin-Converting Enzyme Inhibition , 2006, Circulation.
[42] P. Albertsson,et al. On metronomic chemotherapy: Modulation of angiogenesis mediated by VEGE-A , 2006, Acta oncologica.
[43] Masakazu Toi,et al. Nuclear factor-κB inhibitors as sensitizers to anticancer drugs , 2005, Nature Reviews Cancer.
[44] M. Toi,et al. Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs. , 2005, Nature reviews. Cancer.
[45] J. Silber,et al. Enalapril to prevent cardiac function decline in long-term survivors of pediatric cancer exposed to anthracyclines. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[46] P. Johnston,et al. 5-Fluorouracil: mechanisms of action and clinical strategies , 2003, Nature Reviews Cancer.
[47] H. Yoshiji,et al. Suppression of the renin-angiotensin system attenuates vascular endothelial growth factor-mediated tumor development and angiogenesis in murine hepatocellular carcinoma cells. , 2002, International journal of oncology.
[48] J. Thiery. Epithelial–mesenchymal transitions in tumour progression , 2002, Nature Reviews Cancer.
[49] H. Yoshiji,et al. The angiotensin-I-converting enzyme inhibitor perindopril suppresses tumor growth and angiogenesis: possible role of the vascular endothelial growth factor. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.
[50] L. Murray,et al. Do inhibitors of angiotensin-I-converting enzyme protect against risk of cancer? , 1998, The Lancet.
[51] J. Folkman. What is the evidence that tumors are angiogenesis dependent? , 1990, Journal of the National Cancer Institute.