The Effect of Aqueous Garlic Extract on the Growth of Dermatophytes
暂无分享,去创建一个
ABSTRACT: The effect of aqueous garlic extract on the growth of different medically important dermatophytes was studied. The extract proved to have an inhibitory effect on the growth of Microsporum gypseum, Trichophyton verrucosum, Trichophyton violaceum, Trichophyton rubrum, Trichophyton schoenleini, Trichophyton mentagrophytes and Epidermophyton floccosum. The inhibitory concentration ranged from 130‐200 mg/1. Experimental infection was induced in guinea pigs and rabbits. Treatment of the produced lesions included topical application or injection of the extract. The topical treatment was very effective, producing complete healing in 14 to 17 days following twice daily application of the extract for one week.
[1] G. Moore,et al. The fungicidal and fungistatic effects of an aqueous garlic extract on medically important yeast-like fungi. , 1977, Mycologia.
[2] P. Usunov,et al. [Comparative studies of dermatophyte resistance to antifungal antibiotics. II. Morphological changes]. , 2009, Mykosen.
[3] E. Wills,et al. Enzyme inhibition by allicin, the active principle of garlic. , 1956, The Biochemical journal.