miRNA Regulation of Chondrogenesis

[1]  Tatsuya Kobayashi,et al.  Lin28a overexpression reveals the role of Erk signaling in articular cartilage development , 2018, Development.

[2]  Yan Peng,et al.  Melatonin‐mediated miR‐526b‐3p and miR‐590‐5p upregulation promotes chondrogenic differentiation of human mesenchymal stem cells , 2018, Journal of pineal research.

[3]  L. Jia,et al.  miR-140-5p/miR-149 Affects Chondrocyte Proliferation, Apoptosis, and Autophagy by Targeting FUT1 in Osteoarthritis , 2018, Inflammation.

[4]  Q. Hu,et al.  MicroRNA‐140 Suppresses Human Chondrocytes Hypertrophy by Targeting SMAD1 and Controlling the Bone Morphogenetic Protein Pathway in Osteoarthritis , 2018, The American journal of the medical sciences.

[5]  S. Takada,et al.  Dissecting the roles of miR-140 and its host gene , 2018, Nature Cell Biology.

[6]  E. Paltrinieri,et al.  Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models , 2018, Nature Communications.

[7]  D. Bartel.  Metazoan MicroRNAs , 2018, Cell.

[8]  J. Baron,et al.  mir-374-5p, mir-379-5p, and mir-503-5p Regulate Proliferation and Hypertrophic Differentiation of Growth Plate Chondrocytes in Male Rats , 2018, Endocrinology.

[9]  C. Little,et al.  Cartilage MicroRNA Dysregulation During the Onset and Progression of Mouse Osteoarthritis Is Independent of Aggrecanolysis and Overlaps With Candidates From End‐Stage Human Disease , 2018, Arthritis & rheumatology.

[10]  D. Tiago,et al.  Evidences for a New Role of miR-214 in Chondrogenesis , 2018, Scientific Reports.

[11]  Liqun Jiang,et al.  miR-140-5p/miR-149 Affects Chondrocyte Proliferation, Apoptosis, and Autophagy by Targeting FUT1 in Osteoarthritis , 2018, Inflammation.

[12]  B. Boyan,et al.  MicroRNA Contents in Matrix Vesicles Produced by Growth Plate Chondrocytes are Cell Maturation Dependent , 2018, Scientific Reports.

[13]  M. Soleimani,et al.  Enhanced chondrogenesis differentiation of human induced pluripotent stem cells by MicroRNA-140 and transforming growth factor beta 3 (TGFβ3). , 2018, Biologicals : journal of the International Association of Biological Standardization.

[14]  B. Zhong,et al.  miR‐373 regulates inflammatory cytokine‐mediated chondrocyte proliferation in osteoarthritis by targeting the P2X7 receptor , 2018, FEBS open bio.

[15]  Yue Zhou,et al.  Intermittent cyclic mechanical tension altered the microRNA expression profile of human cartilage endplate chondrocytes , 2018, Molecular medicine reports.

[16]  Yuan Chen,et al.  MALAT1/miR‐127‐5p Regulates Osteopontin (OPN)‐Mediated Proliferation of Human Chondrocytes Through PI3K/Akt Pathway , 2018, Journal of cellular biochemistry.

[17]  K. Malizos,et al.  Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes , 2017, Clinical Epigenetics.

[18]  Peihui Wu,et al.  MicroRNA-92a-3p Regulates Aggrecanase-1 and Aggrecanase-2 Expression in Chondrogenesis and IL-1β-Induced Catabolism in Human Articular Chondrocytes , 2017, Cellular Physiology and Biochemistry.

[19]  X. Shang,et al.  Expression of miR‐206 in Human Knee Articular Chondrocytes and Effects of miR‐206 on Proliferation and Apoptosis of Articular Chondrocytes , 2017, The American journal of the medical sciences.

[20]  A. McAlinden,et al.  miR‐483 targets SMAD4 to suppress chondrogenic differentiation of human mesenchymal stem cells , 2017, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[21]  A. Niehoff,et al.  miR-322 stabilizes MEK1 expression to inhibit RAF/MEK/ERK pathway activation in cartilage , 2017, Development.

[22]  Y. Zeng,et al.  Intra-articular injection of microRNA-140 (miRNA-140) alleviates osteoarthritis (OA) progression by modulating extracellular matrix (ECM) homeostasis in rats. , 2017, Osteoarthritis and cartilage.

[23]  Chuandong Wang,et al.  MicroRNA-145 attenuates TNF-α-driven cartilage matrix degradation in osteoarthritis via direct suppression of MKK4 , 2017, Cell Death and Disease.

[24]  Sik Yoon,et al.  HIF-1α:CRAT:miR-144-3p axis dysregulation promotes osteoarthritis chondrocyte apoptosis and VLCFA accumulation , 2017, Oncotarget.

[25]  F. Gao,et al.  miRNA-101 promotes chondrogenic differentiation in rat bone marrow mesenchymal stem cells , 2017, Experimental and therapeutic medicine.

[26]  Ziqing Li,et al.  miRNA-140 inhibits C3H10T1/2 mesenchymal stem cell proliferation by targeting CXCL12 during transforming growth factor-β3-induced chondrogenic differentiation. , 2017, Molecular medicine reports.

[27]  N. Adachi,et al.  Quality Evaluation of Human Bone Marrow Mesenchymal Stem Cells for Cartilage Repair , 2017, Stem cells international.

[28]  Jianning Zhao,et al.  Long noncoding RNA DANCR regulates miR-1305-Smad 4 axis to promote chondrogenic differentiation of human synovium-derived mesenchymal stem cells , 2017, Bioscience reports.

[29]  Yanli Meng,et al.  miR-127-5p promotes chondrogenic differentiation in rat bone marrow mesenchymal stem cells , 2017, Experimental and therapeutic medicine.

[30]  J. G. Patton,et al.  miR-27 regulates chondrogenesis by suppressing focal adhesion kinase during pharyngeal arch development , 2017, Developmental biology.

[31]  Feng-Sheng Wang,et al.  MicroRNA-29a Counteracts Synovitis in Knee Osteoarthritis Pathogenesis by Targeting VEGF , 2017, Scientific Reports.

[32]  Peng Zhang,et al.  MiR-129-5p Inhibits Proliferation and Invasion of Chondrosarcoma Cells by Regulating SOX4/Wnt/β-Catenin Signaling Pathway , 2017, Cellular Physiology and Biochemistry.

[33]  R. Guldberg,et al.  Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis , 2017, Scientific Reports.

[34]  M. Pantaleon,et al.  Placental O-GlcNAc-transferase expression and interactions with the glucocorticoid receptor are sex specific and regulated by maternal corticosterone exposure in mice , 2017, Scientific Reports.

[35]  Yong Wang,et al.  Decrease of miR-195 Promotes Chondrocytes Proliferation and Maintenance of Chondrogenic Phenotype via Targeting FGF-18 Pathway , 2017, International journal of molecular sciences.

[36]  M. D. de Andrés,et al.  MiR-146b is down-regulated during the chondrogenic differentiation of human bone marrow derived skeletal stem cells and up-regulated in osteoarthritis , 2017, Scientific Reports.

[37]  Chuandong Wang,et al.  miR-146a facilitates osteoarthritis by regulating cartilage homeostasis via targeting Camk2d and Ppp3r2 , 2017, Cell Death & Disease.

[38]  F. Meng,et al.  MicroRNA-92a-3p regulates the expression of cartilage-specific genes by directly targeting histone deacetylase 2 in chondrogenesis and degradation. , 2017, Osteoarthritis and cartilage.

[39]  Shu-Yi Yan,et al.  Effects of microRNA-146a on the proliferation and apoptosis of human osteoarthritis chondrocytes by targeting TRAF6 through the NF-κB signalling pathway , 2017, Bioscience reports.

[40]  C. Pritchard,et al.  Raf Kinases Are Essential for Phosphate Induction of ERK1/2 Phosphorylation in Hypertrophic Chondrocytes and Normal Endochondral Bone Development* , 2017, The Journal of Biological Chemistry.

[41]  F. Meng,et al.  MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation. , 2016, Biochimica et biophysica acta.

[42]  S. Miyaki,et al.  Inhibition of microRNA-222 expression accelerates bone healing with enhancement of osteogenesis, chondrogenesis, and angiogenesis in a rat refractory fracture model. , 2016, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.

[43]  Zhi-yu Huang,et al.  MicroRNA-381 Regulates Chondrocyte Hypertrophy by Inhibiting Histone Deacetylase 4 Expression , 2016, International journal of molecular sciences.

[44]  J. Postlethwait,et al.  MicroRNA Profiling during Craniofacial Development: Potential Roles for Mir23b and Mir133b , 2016, Front. Physiol..

[45]  N. Kops,et al.  Silencing of Antichondrogenic MicroRNA‐221 in Human Mesenchymal Stem Cells Promotes Cartilage Repair In Vivo , 2016, Stem cells.

[46]  J. Post,et al.  Correlation between Gene Expression and Osteoarthritis Progression in Human , 2016, International journal of molecular sciences.

[47]  F. Meng,et al.  MicroRNA-320 regulates matrix metalloproteinase-13 expression in chondrogenesis and interleukin-1β-induced chondrocyte responses. , 2016, Osteoarthritis and cartilage.

[48]  Vicki Rosen,et al.  BMP signalling in skeletal development, disease and repair , 2016, Nature Reviews Endocrinology.

[49]  Ran Guo,et al.  MicroRNA-30a promotes chondrogenic differentiation of mesenchymal stem cells through inhibiting Delta-like 4 expression. , 2016, Life sciences.

[50]  F. Meng,et al.  MiR‐455‐3p regulates early chondrogenic differentiation via inhibiting Runx2 , 2015, FEBS letters.

[51]  Steven Woods,et al.  Genome‐Wide MicroRNA and Gene Analysis of Mesenchymal Stem Cell Chondrogenesis Identifies an Essential Role and Multiple Targets for miR‐140‐5p , 2015, Stem cells.

[52]  M. Gori,et al.  Tissue engineering and microRNAs: future perspectives in regenerative medicine , 2015, Expert opinion on biological therapy.

[53]  R. Blelloch,et al.  Early postnatal ablation of the microRNA-processing enzyme, Drosha, causes chondrocyte death and impairs the structural integrity of the articular cartilage. , 2015, Osteoarthritis and cartilage.

[54]  F. Meng,et al.  The Role of MicroRNA-381 in Chondrogenesis and Interleukin-1-β Induced Chondrocyte Responses , 2015, Cellular Physiology and Biochemistry.

[55]  Marc N. Wein,et al.  MicroRNA‐140 Provides Robustness to the Regulation of Hypertrophic Chondrocyte Differentiation by the PTHrP‐HDAC4 Pathway , 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[56]  S. Murakami,et al.  ERK1 and ERK2 Regulate Chondrocyte Terminal Differentiation During Endochondral Bone Formation , 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[57]  Zi-bo Yang,et al.  MiR‐193b regulates early chondrogenesis by inhibiting the TGF‐beta2 signaling pathway , 2015, FEBS letters.

[58]  Y. Mishina,et al.  BMP-Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse. , 2015, Developmental biology.

[59]  F. Meng,et al.  The Role of MicroRNA-381 in Chondrogenesis and Interleukin-1-β Induced Chondrocyte Responses. , 2015, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.

[60]  Lin Wang,et al.  Association of SOX4 regulated by tumor suppressor miR-30a with poor prognosis in low-grade chondrosarcoma , 2015, Tumor Biology.

[61]  Qing-shui Yin,et al.  PDGF regulates chondrocyte proliferation through activation of the GIT1- and PLCγ1-mediated ERK1/2 signaling pathway. , 2014, Molecular medicine reports.

[62]  F. Mirzamohammadi,et al.  microRNAs in Cartilage Development, Homeostasis, and Disease , 2014, Current Osteoporosis Reports.

[63]  L. Stokes,et al.  The P2X7 Receptor Channel: Recent Developments and the Use of P2X7 Antagonists in Models of Disease , 2014, Pharmacological Reviews.

[64]  Yan Peng,et al.  Melatonin enhances chondrogenic differentiation of human mesenchymal stem cells , 2014, Journal of pineal research.

[65]  E. Canalis.  Wnt signalling in osteoporosis: mechanisms and novel therapeutic approaches , 2013, Nature Reviews Endocrinology.

[66]  E. Paltrinieri,et al.  let-7 and miR-140 microRNAs coordinately regulate skeletal development , 2013, Proceedings of the National Academy of Sciences.

[67]  Yongchang Yao,et al.  ATDC5: An excellent in vitro model cell line for skeletal development , 2013, Journal of cellular biochemistry.

[68]  D. Baltimore,et al.  The Yin and Yang of microRNAs: leukemia and immunity , 2013, Immunological reviews.

[69]  H. Akiyama,et al.  Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development , 2013, Proceedings of the National Academy of Sciences.

[70]  R. Amerongen,et al.  Alternative Wnt Pathways and Receptors , 2012 .

[71]  S. Takada,et al.  L-Sox5 and Sox6 Proteins Enhance Chondrogenic miR-140 MicroRNA Expression by Strengthening Dimeric Sox9 Activity* , 2012, The Journal of Biological Chemistry.

[72]  Joana A. Vidigal,et al.  Germline deletion of the miR-17-92 cluster causes growth and skeletal defects in humans , 2011, Nature genetics.

[73]  Yukio Nakamura,et al.  Chondrocyte-Specific MicroRNA-140 Regulates Endochondral Bone Development and Targets Dnpep To Modulate Bone Morphogenetic Protein Signaling , 2011, Molecular and Cellular Biology.

[74]  John H. Postlethwait,et al.  Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25. , 2011, Nature communications.

[75]  X. Chen,et al.  The E3 ubiquitin ligase Wwp2 regulates craniofacial development through monoubiquitination of Goosecoid , 2010, Nature Cell Biology.

[76]  S. Takada,et al.  MicroRNA-140 plays dual roles in both cartilage development and homeostasis. , 2010, Genes & development.

[77]  M. Lotz,et al.  MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses. , 2009, Arthritis and rheumatism.

[78]  O. Carugo,et al.  A Mek1–Mek2 heterodimer determines the strength and duration of the Erk signal , 2009, Nature Structural &Molecular Biology.

[79]  Takahiro Sato,et al.  Dnm3os, a non‐coding RNA, is required for normal growth and skeletal development in mice , 2008, Developmental dynamics : an official publication of the American Association of Anatomists.

[80]  Keiichiro Nishida,et al.  Expression of microRNA-146 in rheumatoid arthritis synovial tissue. , 2008, Arthritis and rheumatism.

[81]  K. Lyons,et al.  Focal Adhesion Kinase/Src Suppresses Early Chondrogenesis , 2008, Journal of Biological Chemistry.

[82]  A. McMahon,et al.  Dicer-dependent pathways regulate chondrocyte proliferation and differentiation , 2008, Proceedings of the National Academy of Sciences.

[83]  John McAnally,et al.  MEF2C transcription factor controls chondrocyte hypertrophy and bone development. , 2007, Developmental cell.

[84]  C. Hartmann,et al.  Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis , 2006, Development.

[85]  Ji-shuai Zhang,et al.  Smad4 is required for the normal organization of the cartilage growth plate. , 2005, Developmental biology.

[86]  R. Zimmer,et al.  Comparison of the chondrosarcoma cell line SW1353 with primary human adult articular chondrocytes with regard to their gene expression profile and reactivity to IL-1beta. , 2005, Osteoarthritis and cartilage.

[87]  Ken-ichi Inoue,et al.  Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog. , 2004, Genes & development.

[88]  H. Kronenberg,et al.  Developmental regulation of the growth plate , 2003, Nature.

[89]  S. Takeda,et al.  Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. , 2001, Genes & development.

[90]  S. Artavanis-Tsakonas,et al.  Notch signaling: cell fate control and signal integration in development. , 1999, Science.

[91]  Richard R. Behringer,et al.  Sox9 is required for cartilage formation , 1999, Nature Genetics.

[92]  M. Schluchter,et al.  Expression of miR-145-5p During Chondrogenesis of Mesenchymal Stem Cells. , 2017, Journal of stem cell research.

[93]  Yang-Lin Gu,et al.  miR-195 inhibits the proliferation and migration of chondrocytes by targeting GIT1. , 2017, Molecular medicine reports.

[94]  Zhiyu Zhou,et al.  Methylation-mediated silencing of miR-124 facilitates chondrogenesis by targeting NFATc1 under hypoxic conditions. , 2017, American journal of translational research.

[95]  C. Brancolini,et al.  Beside the MEF2 axis: unconventional functions of HDAC4. , 2013, Cellular signalling.

[96]  山本 博充.  Runx2 and Runx3 are essential for chondrocyte maturation and Runx2 regulates limb growth through induction of Indian hedgehog , 2004 .

[97]  R. Tuan,et al.  Murine C3H10T1/2 multipotential cells as an in vitro model of mesenchymal chondrogenesis. , 2000, Methods in molecular biology.