Myeloid-derived suppressor cells are increased in frequency but not maximally suppressive in peripheral blood of Type 1 Diabetes Mellitus patients.

[1]  P. Vyas,et al.  MYELOID NEOPLASIA Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment , 2022 .

[2]  R. Kiessling,et al.  On the armament and appearances of human myeloid-derived suppressor cells. , 2012, Clinical immunology.

[3]  R. Weissleder,et al.  Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging , 2012, Nature Immunology.

[4]  L. Wen,et al.  The Role of Gr1+ Cells after Anti-CD20 Treatment in Type 1 Diabetes in Nonobese Diabetic Mice , 2012, The Journal of Immunology.

[5]  M. Manns,et al.  Myeloid derived suppressor cells in human diseases. , 2011, International immunopharmacology.

[6]  J. G. Cripps,et al.  MDSC in autoimmunity. , 2011, International immunopharmacology.

[7]  F. de Castro,et al.  Myeloid‐Derived Suppressor Cells Limit the Inflammation by Promoting T Lymphocyte Apoptosis in the Spinal Cord of a Murine Model of Multiple Sclerosis , 2011, Brain pathology.

[8]  C. Divino,et al.  Myeloid-Derived Suppressor Cells Prevent Type 1 Diabetes in Murine Models , 2010, The Journal of Immunology.

[9]  A. Epstein,et al.  Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells , 2010, The Journal of Immunology.

[10]  Jeffrey A. Bluestone,et al.  Genetics, pathogenesis and clinical interventions in type 1 diabetes , 2010, Nature.

[11]  Thomas B. Kepler,et al.  β Cell-Specific CD4+ T Cell Clonotypes in Peripheral Blood and the Pancreatic Islets Are Distinct1 , 2009, The Journal of Immunology.

[12]  T. Padhya,et al.  Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells1 , 2009, The Journal of Immunology.

[13]  Srinivas Nagaraj,et al.  Myeloid-derived suppressor cells as regulators of the immune system , 2009, Nature Reviews Immunology.

[14]  M. Manns,et al.  Myeloid-derived suppressor cells in inflammatory bowel disease: a new immunoregulatory pathway. , 2008, Gastroenterology.

[15]  P. Rodriguez,et al.  Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives , 2008, Immunological reviews.

[16]  P. De Baetselier,et al.  Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. , 2008, Blood.

[17]  V. Kuchroo,et al.  CD11b+Ly-6Chi Suppressive Monocytes in Experimental Autoimmune Encephalomyelitis1 , 2007, The Journal of Immunology.

[18]  J. Talmadge.  Pathways Mediating the Expansion and Immunosuppressive Activity of Myeloid-Derived Suppressor Cells and Their Relevance to Cancer Therapy , 2007, Clinical Cancer Research.

[19]  M. Colombo,et al.  The terminology issue for myeloid-derived suppressor cells. , 2007, Cancer research.

[20]  C. Divino,et al.  Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. , 2006, Cancer research.

[21]  D. Gabrilovich,et al.  STAT1 Signaling Regulates Tumor-Associated Macrophage-Mediated T Cell Deletion1 , 2005, The Journal of Immunology.

[22]  D. Gabrilovich,et al.  Antigen-Specific Inhibition of CD8+ T Cell Response by Immature Myeloid Cells in Cancer Is Mediated by Reactive Oxygen Species1 , 2004, The Journal of Immunology.

[23]  Shu-Hsia Chen,et al.  Gr-1+ Myeloid Cells Derived from Tumor-Bearing Mice Inhibit Primary T Cell Activation Induced Through CD3/CD28 Costimulation1 , 2000, The Journal of Immunology.

[24]  P. Holt,et al.  Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway. , 1998, Journal of immunology.

[25]  C. Janeway,et al.  CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells , 1996, The Journal of experimental medicine.

[26]  T. Malek,et al.  Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family. , 1993, Journal of immunology.

[27]  L. Harrison,et al.  Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice. , 1991, The Journal of clinical investigation.

[28]  K. Lafferty,et al.  Pancreatic islet-specific T-cell clones from nonobese diabetic mice. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[29]  W. Gepts.  Pathologic Anatomy of the Pancreas in Juvenile Diabetes Mellitus , 1965, Diabetes.