Role of endothelial shear stress in stent restenosis and thrombosis: pathophysiologic mechanisms and implications for clinical translation.

[1]  Dimitrios I Fotiadis,et al.  Relationship of shear stress with in-stent restenosis: bare metal stenting and the effect of brachytherapy. , 2009, International journal of cardiology.

[2]  Bernard Chevalier,et al.  Angiographic geometric changes of the lumen arterial wall after bioresorbable vascular scaffolds and metallic platform stents at 1-year follow-up. , 2011, JACC. Cardiovascular interventions.

[3]  J J Wentzel,et al.  Relationship Between Neointimal Thickness and Shear Stress After Wallstent Implantation in Human Coronary Arteries , 2001, Circulation.

[4]  Ward Casscells,et al.  Migration of Smooth Muscle and Endothelial Cells: Critical Events in Restenosis , 1992, Circulation.

[5]  Michail I. Papafaklis,et al.  Natural History of Experimental Coronary Atherosclerosis and Vascular Remodeling in Relation to Endothelial Shear Stress: A Serial, In Vivo Intravascular Ultrasound Study , 2010, Circulation.

[6]  E. Edelman,et al.  Prediction of the Localization of High-Risk Coronary Atherosclerotic Plaques on the Basis of Low Endothelial Shear Stress: An Intravascular Ultrasound and Histopathology Natural History Study , 2008, Circulation.

[7]  Johan Lindbäck,et al.  Long-term outcomes with drug-eluting stents versus bare-metal stents in Sweden. , 2007, The New England journal of medicine.

[8]  Shao-Liang Chen,et al.  Perspective on bifurcation PCI. , 2009, Journal of interventional cardiology.

[9]  Attila Thury,et al.  Images in cardiovascular medicine. Focal in-stent restenosis near step-up: roles of low and oscillating shear stress? , 2002, Circulation.

[10]  C. Di Mario,et al.  In-stent restenosis in small coronary arteries: impact of strut thickness. , 2002, Journal of the American College of Cardiology.

[11]  A. Tzafriri,et al.  Luminal flow patterns dictate arterial drug deposition in stent-based delivery. , 2009, Journal of controlled release : official journal of the Controlled Release Society.

[12]  A. Kastrati,et al.  Influence of stent surface topography on the outcomes of patients undergoing coronary stenting: A randomized double‐blind controlled trial , 2005, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[13]  Yiannis S Chatzizisis,et al.  The role of low endothelial shear stress in the conversion of atherosclerotic lesions from stable to unstable plaque , 2009, Current opinion in cardiology.

[14]  P. Teirstein,et al.  Contribution of Stent Underexpansion to Recurrence After Sirolimus-Eluting Stent Implantation for In-Stent Restenosis , 2004, Circulation.

[15]  E. Edelman,et al.  Dynamic flow alterations dictate leukocyte adhesion and response to endovascular interventions. , 2004, The Journal of clinical investigation.

[16]  M. Shibuya,et al.  PE-414 Correlation of ventricular dyssynchrony to infarct size and remodeling after reperfused myocardial infarction : Study with real-time 3D echocardiography(Echo/Doppler(08)(I),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society) , 2008 .

[17]  Richard T. Schoephoerster,et al.  Spatial Distribution of Platelet Deposition in Stented Arterial Models Under Physiologic Flow , 2005, Annals of Biomedical Engineering.

[18]  D. Tang,et al.  Pattern formation of vascular smooth muscle cells subject to nonuniform fluid shear stress: role of PDGF-beta receptor and Src. , 2003, American journal of physiology. Heart and circulatory physiology.

[19]  Nikos Stergiopulos,et al.  Augmentation of Wall Shear Stress Inhibits Neointimal Hyperplasia After Stent Implantation: Inhibition Through Reduction of Inflammation? , 2003, Circulation.

[20]  D. Fingar,et al.  The mTOR/p70 S6K1 pathway regulates vascular smooth muscle cell differentiation. , 2004, American journal of physiology. Cell physiology.

[21]  R. Virmani,et al.  Coronary responses and differential mechanisms of late stent thrombosis attributed to first-generation sirolimus- and paclitaxel-eluting stents. , 2011, Journal of the American College of Cardiology.

[22]  C. Di Mario,et al.  Stented segment length as an independent predictor of restenosis. , 1999, Journal of the American College of Cardiology.

[23]  G. Schuler,et al.  Influence of residual stenosis after percutaneous coronary intervention with stent implantation on development of restenosis and stent thrombosis. , 2003, The American journal of cardiology.

[24]  D Glogar,et al.  Longitudinal straightening effect of stents is an additional predictor for major adverse cardiac events. Austrian Wiktor Stent Study Group and European Paragon Stent Investigators. , 2000, Journal of the American College of Cardiology.

[25]  P. Serruys,et al.  Coronary stents: current status. , 2010, Journal of the American College of Cardiology.

[26]  Renu Virmani,et al.  Pathological findings at bifurcation lesions: the impact of flow distribution on atherosclerosis and arterial healing after stent implantation. , 2010, Journal of the American College of Cardiology.

[27]  P. Stone,et al.  In vivo assessment of local intravascular hemodynamics and arterial morphology to investigate vascular outcomes: a growing field coming of age. , 2010, JACC. Cardiovascular interventions.

[28]  John F LaDisa,et al.  Alterations in wall shear stress predict sites of neointimal hyperplasia after stent implantation in rabbit iliac arteries. , 2005, American journal of physiology. Heart and circulatory physiology.

[29]  P. Teirstein,et al.  Restenosis After Placement of Palmaz‐Schatz Stents in Native Coronary Arteries: Initial Results of a Multicenter Experience , 1992, Circulation.

[30]  A. Kastrati,et al.  Intracoronary Stenting and Angiographic Results: Strut Thickness Effect on Restenosis Outcome (ISAR-STEREO) Trial , 2001, Circulation.

[31]  S. Windecker,et al.  Late Coronary Stent Thrombosis , 2007, Circulation.

[32]  E. Edelman,et al.  Cardiology is flow. , 2006, Circulation.

[33]  P. Serruys,et al.  Usefulness of shear stress pattern in predicting neointima distribution in sirolimus-eluting stents in coronary arteries. , 2003, The American journal of cardiology.

[34]  Michael Jonas,et al.  Augmented Expression and Activity of Extracellular Matrix-Degrading Enzymes in Regions of Low Endothelial Shear Stress Colocalize With Coronary Atheromata With Thin Fibrous Caps in Pigs , 2011, Circulation.

[35]  E. Edelman,et al.  Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior. , 2007, Journal of the American College of Cardiology.

[36]  Sanjay Pant,et al.  The Influence of Strut-Connectors in Stented Vessels: A Comparison of Pulsatile Flow Through Five Coronary Stents , 2010, Annals of Biomedical Engineering.

[37]  Francesco Migliavacca,et al.  Effects of different stent designs on local hemodynamics in stented arteries. , 2008, Journal of biomechanics.

[38]  E. Edelman,et al.  Endovascular stent design dictates experimental restenosis and thrombosis. , 1995, Circulation.

[39]  E. Edelman,et al.  Smooth Muscle Cells Orchestrate the Endothelial Cell Response to Flow and Injury , 2010, Circulation.

[40]  A. Kastrati,et al.  [Intracoronary Stenting and Angiographic Results Strut Thickness Effect on Restenosis Outcome (ISAR-STEREO) Trial]. , 2012, Vestnik rentgenologii i radiologii.

[41]  A. Kastrati,et al.  Comparative characterization of cellular and molecular anti-restenotic profiles of paclitaxel and sirolimus , 2007, Thrombosis and Haemostasis.

[42]  S. Glagov,et al.  Increased flow and shear stress enhance in vivo transforming growth factor-beta1 after experimental arterial injury. , 2000, Arteriosclerosis, thrombosis, and vascular biology.

[43]  V. Rizzo.  Enhanced interstitial flow as a contributing factor in neointima formation: (shear) stressing vascular wall cell types other than the endothelium. , 2009, American journal of physiology. Heart and circulatory physiology.

[44]  C. Heldin,et al.  Different Effects of High and Low Shear Stress on Platelet-Derived Growth Factor Isoform Release by Endothelial Cells: Consequences for Smooth Muscle Cell Migration , 2002, Arteriosclerosis, thrombosis, and vascular biology.

[45]  Michael Joner,et al.  Pathology of drug-eluting stents in humans: delayed healing and late thrombotic risk. , 2006, Journal of the American College of Cardiology.

[46]  Michail I. Papafaklis,et al.  Coronary dilatation 10 weeks after paclitaxel-eluting stent implantation. No role of shear stress in lumen enlargement? , 2007, Heart and Vessels.

[47]  E. Edelman,et al.  Stent Thrombogenicity Early in High-Risk Interventional Settings Is Driven by Stent Design and Deployment and Protected by Polymer-Drug Coatings , 2011, Circulation.

[48]  R. Virmani,et al.  Differential Response of Delayed Healing and Persistent Inflammation at Sites of Overlapping Sirolimus- or Paclitaxel-Eluting Stents , 2005, Circulation.

[49]  O. McDonald,et al.  Atherosclerosis-prone hemodynamics differentially regulates endothelial and smooth muscle cell phenotypes and promotes pro-inflammatory priming. , 2007, American journal of physiology. Cell physiology.

[50]  T. Sasaguri,et al.  Laminar shear stress inhibits vascular endothelial cell proliferation by inducing cyclin-dependent kinase inhibitor p21(Sdi1/Cip1/Waf1) , 2000, Circulation research.

[51]  A. Maseri,et al.  Histopathology of clinical coronary restenosis in drug-eluting versus bare metal stents. , 2009, The American journal of cardiology.

[52]  F. Eberli,et al.  Impact of stent overlap on angiographic and long-term clinical outcome in patients undergoing drug-eluting stent implantation. , 2010, Journal of the American College of Cardiology.

[53]  T. Yaginuma,et al.  Shear stress as an inhibitor of vascular smooth muscle cell proliferation. Role of transforming growth factor-beta 1 and tissue-type plasminogen activator. , 1997, Arteriosclerosis, thrombosis, and vascular biology.

[54]  R. Virmani,et al.  Drug eluting stents: are human and animal studies comparable? , 2003, Heart.

[55]  Y. Matsumoto,et al.  Does stent design affect probability of restenosis? A randomized trial comparing Multilink stents with GFX stents. , 2001, American heart journal.

[56]  N. Ohshima,et al.  Endovascular stent configuration affects intraluminal flow dynamics and in vitro endothelialization. , 2004, Biorheology.

[57]  Johan Lindbäck,et al.  Long-term safety and efficacy of drug-eluting versus bare-metal stents in Sweden. , 2009, The New England journal of medicine.

[58]  T. Stijnen,et al.  Late stent malapposition risk is higher after drug-eluting stent compared with bare-metal stent implantation and associates with late stent thrombosis. , 2010, European heart journal.

[59]  J. LaDisa,et al.  Three-Dimensional Computational Fluid Dynamics Modeling of Alterations in Coronary Wall Shear Stress Produced by Stent Implantation , 2003, Annals of Biomedical Engineering.

[60]  M. S. Williams,et al.  Stent and artery geometry determine intimal thickening independent of arterial injury. , 2000, Circulation.

[61]  K Ulm,et al.  Restenosis after coronary placement of various stent types. , 2001, The American journal of cardiology.

[62]  A. Wahle,et al.  Effect of Endothelial Shear Stress on the Progression of Coronary Artery Disease, Vascular Remodeling, and In-Stent Restenosis in Humans: In Vivo 6-Month Follow-Up Study , 2003, Circulation.

[63]  P. Davies,et al.  Spatial hemodynamics, the endothelium, and focal atherogenesis: a cell cycle link? , 2000, Circulation research.

[64]  D. Lawrence,et al.  Endothelial Cells Inhibit Flow-Induced Smooth Muscle Cell Migration: Role of Plasminogen Activator Inhibitor-1 , 2001, Circulation.

[65]  Nandini Duraiswamy,et al.  Comparison of near-wall hemodynamic parameters in stented artery models. , 2009, Journal of biomechanical engineering.

[66]  Yiannis S Chatzizisis,et al.  Flow and atherosclerosis in coronary bifurcations. , 2010, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

[67]  Timothy J. Gundert,et al.  Local hemodynamic changes caused by main branch stent implantation and subsequent virtual side branch balloon angioplasty in a representative coronary bifurcation. , 2010, Journal of applied physiology.

[68]  C. García,et al.  Influencia de la tensión de cizallamiento en la reestenosis intra-stent: estudio in vivo con reconstrucción 3D y dinámica de fluidos computacional , 2006 .

[69]  Luoding Zhu,et al.  Effects of stent sizing on endothelial and vessel wall stress: potential mechanisms for in-stent restenosis. , 2009, Journal of applied physiology.

[70]  E. Edelman,et al.  Luminal Flow Amplifies Stent-Based Drug Deposition in Arterial Bifurcations , 2009, PloS one.

[71]  John P A Ioannidis,et al.  Double Versus Single Stenting for Coronary Bifurcation Lesions: A Meta-Analysis , 2009, Circulation. Cardiovascular interventions.

[72]  Antonio Crespo,et al.  [Influence of shear stress on in-stent restenosis: in vivo study using 3D reconstruction and computational fluid dynamics]. , 2006, Revista espanola de cardiologia.

[73]  J J Wentzel,et al.  Coronary stent implantation changes 3-D vessel geometry and 3-D shear stress distribution. , 2000, Journal of biomechanics.

[74]  P. Davies,et al.  Hemodynamically Driven Stent Strut Design , 2009, Annals of Biomedical Engineering.

[75]  Dimitrios I Fotiadis,et al.  The effect of shear stress on neointimal response following sirolimus- and paclitaxel-eluting stent implantation compared with bare-metal stents in humans. , 2010, JACC. Cardiovascular interventions.

[76]  R. Virmani,et al.  Pathological Correlates of Late Drug-Eluting Stent Thrombosis: Strut Coverage as a Marker of Endothelialization , 2007, Circulation.

[77]  Michael C. McDaniel,et al.  Coronary Artery Wall Shear Stress Is Associated With Progression and Transformation of Atherosclerotic Plaque and Arterial Remodeling in Patients With Coronary Artery Disease , 2011, Circulation.

[78]  Rosaire Mongrain,et al.  Evaluation of the effect of stent strut profile on shear stress distribution using statistical moments , 2009, Biomedical engineering online.

[79]  C. Macaya,et al.  Variability in individual responsiveness to clopidogrel: clinical implications, management, and future perspectives. , 2007, Journal of the American College of Cardiology.

[80]  Ju Han Kim,et al.  Inflammation and delayed endothelization with overlapping drug-eluting stents in a porcine model of in-stent restenosis. , 2008, Circulation journal : official journal of the Japanese Circulation Society.

[81]  Renu Virmani,et al.  Pathological Mechanisms of Fatal Late Coronary Stent Thrombosis in Humans , 2003, Circulation.

[82]  Antonio Colombo,et al.  Randomized Study to Evaluate Sirolimus-Eluting Stents Implanted at Coronary Bifurcation Lesions , 2004, Circulation.

[83]  J. Tobis,et al.  Bifurcation lesions: two stents versus one stent--immediate and follow-up results. , 2000, Journal of the American College of Cardiology.

[84]  Pavlos Vlachos,et al.  In Vitro Comparison of the Effect of Stent Configuration on Wall Shear Stress Using Time-resolved Particle Image Velocimetry , 2010, Annals of Biomedical Engineering.

[85]  C. Macaya,et al.  Assessment of potential relationship between wall shear stress and arterial wall response after bare metal stent and sirolimus-eluting stent implantation in patients with diabetes mellitus , 2008, The International Journal of Cardiovascular Imaging.