Role of transforming growth factor-β in airway remodeling in asthma.
暂无分享,去创建一个
[1] D. Davies. The role of the epithelium in airway remodeling in asthma. , 2009, Proceedings of the American Thoracic Society.
[2] C. Hawrylowicz,et al. Regulatory T cells in asthma. , 2009, Immunity.
[3] J. Martin,et al. Platelet‐derived growth factor and transforming growth factor‐β modulate the expression of matrix metalloproteinases and migratory function of human airway smooth muscle cells , 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[4] D. Knight,et al. Induction of epithelial-mesenchymal transition in primary airway epithelial cells from patients with asthma by transforming growth factor-beta1. , 2009, American journal of respiratory and critical care medicine.
[5] M. Sanak,et al. Asthmatic bronchial fibroblasts demonstrate enhanced potential to differentiate into myofibroblasts in culture. , 2009, Medical science monitor : international medical journal of experimental and clinical research.
[6] M. Jordana,et al. Transforming growth factor-beta regulates house dust mite-induced allergic airway inflammation but not airway remodeling. , 2008, American journal of respiratory and critical care medicine.
[7] R. Sorkness,et al. Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis. , 2008, The Journal of clinical investigation.
[8] P. Weinreb,et al. Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-induced Lung Fibrosis , 2008 .
[9] Nicola J. Rinaldi,et al. Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation , 2008 .
[10] D. Broide,et al. Cytokines and growth factors in airway remodeling in asthma. , 2007, Current opinion in immunology.
[11] M. Hew,et al. Expression and activation of TGF-β isoforms in acute allergen-induced remodelling in asthma , 2007, Thorax.
[12] B. Camoretti-Mercado,et al. Transforming growth factor-β1 and disorders of the lung , 2007, Cell Biochemistry and Biophysics.
[13] D. Postma,et al. Remodeling in asthma and chronic obstructive pulmonary disease. , 2006, Proceedings of the American Thoracic Society.
[14] K. Yamauchi. Airway remodeling in asthma and its influence on clinical pathophysiology. , 2006, The Tohoku journal of experimental medicine.
[15] K. Chung,et al. Neutrophil-Derived Elastase Induces TGF-β1 Secretion in Human Airway Smooth Muscle via NF-κB Pathway , 2006 .
[16] J. Sok,et al. Differential diagnosis of eosinophilic chronic rhinosinusitis , 2006, Current allergy and asthma reports.
[17] N. Khalil,et al. TGF-β1 increases proliferation of airway smooth muscle cells by phosphorylation of map kinases , 2006, Respiratory research.
[18] G. Menz,et al. Activin A is an acute allergen-responsive cytokine and provides a link to TGF-beta-mediated airway remodeling in asthma. , 2006, The Journal of allergy and clinical immunology.
[19] D. Broide,et al. Corticosteroids prevent myofibroblast accumulation and airway remodeling in mice. , 2006, American journal of physiology. Lung cellular and molecular physiology.
[20] V. Duronio,et al. Proliferation of Pulmonary Interstitial Fibroblasts Is Mediated by Transforming Growth Factor-β1-induced Release of Extracellular Fibroblast Growth Factor-2 and Phosphorylation of p38 MAPK and JNK* , 2005, Journal of Biological Chemistry.
[21] J. Varga,et al. Eosinophil-fibroblast interactions induce fibroblast IL-6 secretion and extracellular matrix gene expression: implications in fibrogenesis. , 2005, The Journal of allergy and clinical immunology.
[22] Jesús Prieto,et al. Topical application of a peptide inhibitor of transforming growth factor-beta1 ameliorates bleomycin-induced skin fibrosis. , 2005, The Journal of investigative dermatology.
[23] S. Leivonen,et al. Smad3 and extracellular signal-regulated kinase 1/2 coordinately mediate transforming growth factor-beta-induced expression of connective tissue growth factor in human fibroblasts. , 2005, The Journal of investigative dermatology.
[24] Sarah J. McMillan,et al. Manipulation of Allergen-Induced Airway Remodeling by Treatment with Anti-TGF-β Antibody: Effect on the Smad Signaling Pathway1 , 2005, The Journal of Immunology.
[25] S. Fukuhara,et al. Relationship of airway wall thickening to an imbalance between matrix metalloproteinase-9 and its inhibitor in asthma , 2005, Thorax.
[26] S. Rennard,et al. Smad3 mediates TGF-beta1 induction of VEGF production in lung fibroblasts. , 2005, Biochemical and biophysical research communications.
[27] S. Wahl,et al. Transforming growth factor-β-induced regulatory T cells referee inflammatory and autoimmune diseases , 2005, Arthritis research & therapy.
[28] S. Wenzel,et al. Increased TGF-β2 in severe asthma with eosinophilia , 2005 .
[29] Jian Li,et al. Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling. , 2004, Cytokine.
[30] S. Wenzel,et al. Transforming growth factor-beta2 induces bronchial epithelial mucin expression in asthma. , 2004, The American journal of pathology.
[31] D. Dorscheid,et al. Smad and p38-MAPK signaling mediates apoptotic effects of transforming growth factor-beta1 in human airway epithelial cells. , 2004, American journal of physiology. Lung cellular and molecular physiology.
[32] C. di Ilio,et al. Review: Pharmacological treatment of airway remodeling: inhaled corticosteroids or antileukotrienes? , 2004, Annals of clinical and laboratory science.
[33] D. Broide,et al. Inhibition of airway remodeling in IL-5-deficient mice. , 2004, The Journal of clinical investigation.
[34] S. Rennard,et al. Interferon-γ Inhibits Transforming Growth Factor-β Production in Human Airway Epithelial Cells by Targeting Smads , 2004 .
[35] M. Kitagawa,et al. Treatment with anti-TGF-β antibody ameliorates chronic progressive nephritis by inhibiting Smad/TGF-β signaling , 2004 .
[36] Hiroshi Tanaka,et al. Increased airway vascularity in newly diagnosed asthma using a high-magnification bronchovideoscope. , 2003, American journal of respiratory and critical care medicine.
[37] Reynold A Panettieri,et al. Is airway remodeling clinically relevant in asthma? , 2003, The American journal of medicine.
[38] Ying E. Zhang,et al. Smad-dependent and Smad-independent pathways in TGF-β family signalling , 2003, Nature.
[39] S. Phipps,et al. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. , 2003, The Journal of clinical investigation.
[40] L. Boulet,et al. Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-beta, IL-11, IL-17, and type I and type III collagen expression. , 2003, The Journal of allergy and clinical immunology.
[41] Q. Hamid,et al. Polarized in vivo expression of IL-11 and IL-17 between acute and chronic skin lesions. , 2003, The Journal of allergy and clinical immunology.
[42] G. Bonsignore,et al. Airway remodeling in asthma. , 2003, Chest.
[43] P. Khaw,et al. Novel antisense oligonucleotides targeting TGF-β inhibit in vivo scarring and improve surgical outcome , 2003, Gene Therapy.
[44] K. Chung,et al. Matrix metalloproteinase-9 expression in asthma: effect of asthma severity, allergen challenge, and inhaled corticosteroids. , 2002, Chest.
[45] D. Sheppard,et al. Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma , 2002, Nature Medicine.
[46] P. Foster,et al. Role of interleukin‐13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma , 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[47] B. Olson,et al. Inhibition of Transforming Growth Factor (TGF)- 1–Induced Extracellular Matrix with a Novel Inhibitor of the TGF- Type I Receptor Kinase Activity: SB-431542 , 2002 .
[48] I. Hall,et al. Effects of growth factors and extracellular matrix on survival of human airway smooth muscle cells. , 2001, American journal of respiratory cell and molecular biology.
[49] J. Keski‐Oja,et al. Latency, activation, and binding proteins of TGF‐β , 2001, Microscopy research and technique.
[50] K. Sharma,et al. Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[51] G. Berry,et al. CD4(+) T helper cells engineered to produce latent TGF-beta1 reverse allergen-induced airway hyperreactivity and inflammation. , 2000, The Journal of clinical investigation.
[52] Yan Zhang,et al. Anti-TGF-beta treatment prevents skin and lung fibrosis in murine sclerodermatous graft-versus-host disease: a model for human scleroderma. , 1999, Journal of immunology.
[53] K. Shirato,et al. Morphometric analysis of bronchial cartilage in chronic obstructive pulmonary disease and bronchial asthma. , 1999, American journal of respiratory and critical care medicine.
[54] N. Kaminski,et al. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. , 1999, Cell.
[55] P. Hiemstra,et al. Transforming Growth Factor β1 and Recruitment of Macrophages and Mast Cells in Airways in Chronic Obstructive Pulmonary Disease , 1998 .
[56] P. Howarth,et al. Co‐localization of immunoreactive transforming growth factor‐beta1 and decorin in bronchial biopsies from asthmatic and normal subjects , 1998, The Journal of pathology.
[57] Y. Nakamura,et al. Expression of growth factors and remodelling of the airway wall in bronchial asthma. , 1998, Thorax.
[58] R. Martin,et al. Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma. , 1997, American journal of respiratory cell and molecular biology.
[59] J. Bousquet,et al. Transforming Growth Factor- β Expression in Mucosal Biopsies in Asthma and Chronic Bronchitis , 1997 .
[60] P. Howarth,et al. Transforming growth factor-beta 1 in asthma. Measurement in bronchoalveolar lavage fluid. , 1997, American journal of respiratory and critical care medicine.
[61] R. D. du Bois,et al. Diverse cellular TGF-beta 1 and TGF-beta 3 gene expression in normal human and murine lung. , 1996, The European respiratory journal.
[62] M. Jordana,et al. Transforming growth factor beta 1 (TGF beta 1) gene expression by eosinophils in asthmatic airway inflammation. , 1996, American journal of respiratory cell and molecular biology.
[63] S. Wahl,et al. Transforming growth factor beta: the good, the bad, and the ugly , 1994, The Journal of experimental medicine.
[64] G. Simonneau,et al. Transforming growth factor beta in normal human lung: preferential location in bronchial epithelial cells. , 1994, Thorax.
[65] J. Hogg,et al. Transforming growth factor beta 1 gene expression in human airways. , 1994, Thorax.
[66] A. James,et al. The structure of large and small airways in nonfatal and fatal asthma. , 1993, The American review of respiratory disease.
[67] M. Sporn,et al. Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[68] M. Ebina,et al. Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack. , 1992, Chest.
[69] T Takishima,et al. Site of airway obstruction in pulmonary disease: direct measurement of intrabronchial pressure. , 1992, Journal of applied physiology.
[70] S. Wahl,et al. Type I transforming growth factor-beta receptors on neutrophils mediate chemotaxis to transforming growth factor-beta. , 1991, Journal of immunology.
[71] E. Kovacs,et al. Transforming Growth Factor-β Production by Lung Macrophages and Fibroblasts , 1991 .
[72] R. Todd,et al. Human eosinophils express transforming growth factor alpha , 1990, The Journal of experimental medicine.
[73] S. Holgate,et al. SUBEPITHELIAL FIBROSIS IN THE BRONCHI OF ASTHMATICS , 1989, The Lancet.
[74] B. Naylor. The Shedding of the Mucosa of the Bronchial Tree in Asthma , 1962, Thorax.