CD4+CD25+ T Cell-Dependent Inhibition of Autoimmunity in Transgenic Mice Overexpressing Human Bcl-2 in T Lymphocytes1
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M. González-Gay | L. Buelta | M. López-Hoyos | J. Merino | S. Izui | R. Merino | E. Tamayo | Inés Santiuste | R. Marquina | Jovanna González
[1] J. Ortaldo,et al. Pertussis toxin as an adjuvant suppresses the number and function of CD4+CD25+ T regulatory cells , 2006, European journal of immunology.
[2] S. Jameson,et al. Central tolerance: learning self-control in the thymus , 2005, Nature Reviews Immunology.
[3] G. Dennert,et al. High Sensitivity of CD4+CD25+ Regulatory T Cells to Extracellular Metabolites Nicotinamide Adenine Dinucleotide and ATP: A Role for P2X7 Receptors1 , 2005, The Journal of Immunology.
[4] P. Krammer,et al. Cutting Edge: In Contrast to Effector T Cells, CD4+CD25+FoxP3+ Regulatory T Cells Are Highly Susceptible to CD95 Ligand- but Not to TCR-Mediated Cell Death1 , 2005, The Journal of Immunology.
[5] C. Goodnow,et al. Cellular and genetic mechanisms of self tolerance and autoimmunity , 2005, Nature.
[6] A. Singer,et al. CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2 , 2005, Nature Immunology.
[7] C. June,et al. CD4+CD25+ regulatory T-cell lines from human cord blood have functional and molecular properties of T-cell anergy. , 2004, Blood.
[8] S. Sakaguchi,et al. CD4+ Tregs and immune control. , 2004, The Journal of clinical investigation.
[9] L. Chess,et al. An integrated view of suppressor T cell subsets in immunoregulation. , 2004, The Journal of clinical investigation.
[10] M. Arias,et al. Inhibition of B Cell Death Causes the Development of an IgA Nephropathy in (New Zealand White × C57BL/6)F1-bcl-2 Transgenic Mice1 , 2004, The Journal of Immunology.
[11] Xin Chen,et al. Differential response of murine CD4+CD25+ and CD4+CD25– T cells to dexamethasone‐induced cell death , 2004, European journal of immunology.
[12] A. Strasser,et al. Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more. , 2003, Annual review of immunology.
[13] E. Esplugues,et al. CD69 downregulates autoimmune reactivity through active transforming growth factor-beta production in collagen-induced arthritis. , 2003, The Journal of clinical investigation.
[14] M. Nussenzweig,et al. Predominant Autoantibody Production by Early Human B Cell Precursors , 2003, Science.
[15] M. López-Hoyos,et al. Defects in the regulation of B cell apoptosis are required for the production of citrullinated peptide autoantibodies in mice. , 2003, Arthritis and rheumatism.
[16] A. Orlofsky,et al. A1 is a growth-permissive antiapoptotic factor mediating postactivation survival in T cells. , 2003, Blood.
[17] F. Ramsdell,et al. An essential role for Scurfin in CD4+CD25+ T regulatory cells , 2003, Nature Immunology.
[18] R. Schwartz. T cell anergy. , 2003, Annual review of immunology.
[19] A. Rudensky,et al. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells , 2003, Nature Immunology.
[20] T. Nomura,et al. Control of Regulatory T Cell Development by the Transcription Factor Foxp3 , 2002 .
[21] L. Klein,et al. Origin of regulatory T cells with known specificity for antigen , 2002, Nature Immunology.
[22] A. Strasser,et al. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. , 2002, Immunity.
[23] A. Strasser,et al. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes , 2002, Nature.
[24] M. Boothby,et al. Constitutive expression of BCL-X(L) in the T lineage attenuates collagen-induced arthritis in Bcl-X(L) transgenic mice. , 2002, Arthritis and rheumatism.
[25] Hans D. Ochs,et al. A rare polyadenylation signal mutation of the FOXP3 gene (AAUAAA→AAUGAA) leads to the IPEX syndrome , 2001, Immunogenetics.
[26] M. Salmon,et al. Human anergic/suppressive CD4+CD25+ T cells: a highly differentiated and apoptosis‐prone population , 2001, European journal of immunology.
[27] A. Naji,et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide , 2001, Nature Immunology.
[28] P. Kourilsky,et al. Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion. , 2000, Immunity.
[29] S. Khoury,et al. Role of passive T-cell death in chronic experimental autoimmune encephalomyelitis. , 2000, The Journal of clinical investigation.
[30] J. Bluestone,et al. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. , 2000, Immunity.
[31] A. Strasser,et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. , 1999, Science.
[32] G. Núñez,et al. Constitutive expression of bcl-2 in B cells causes a lethal form of lupuslike autoimmune disease after induction of neonatal tolerance to H- 2b alloantigens , 1996, The Journal of experimental medicine.
[33] F. Finkelman,et al. bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice , 1996, The Journal of experimental medicine.
[34] G. Kelsoe,et al. In situ studies of the primary immune response to (4-hydroxy-3- nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self- tolerance , 1995, The Journal of experimental medicine.
[35] G. Núñez,et al. Modulation of anti-IgM-induced B cell apoptosis by Bcl-xL and CD40 in WEHI-231 cells. Dissociation from cell cycle arrest and dependence on the avidity of the antibody-IgM receptor interaction. , 1995, Journal of immunology.
[36] M. Toda,et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. , 1995, Journal of immunology.
[37] C. Thompson,et al. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. , 1995, Immunity.
[38] S. Ju,et al. Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation , 1995, Nature.
[39] Satoru Takahashi,et al. Effect of Long-Term Anti-CD4 or Anti-CD8 Treatment on the Development oflprCD4−CD8−Double Negative T Cells and of the Autoimmune Syndrome in MRL-lpr/lprMice , 1995 .
[40] G. Núñez,et al. Bcl-2 and Bcl-x: regulatory switches for lymphoid death and survival. , 1994, Immunology today.
[41] G. Linette,et al. Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points. , 1994, Immunity.
[42] M. Cooke,et al. Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death , 1993, Cell.
[43] J C Reed,et al. Differential effects of Bcl-2 on T and B cells in transgenic mice. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[44] John Calvin Reed,et al. Inhibition of thymocyte apoptosis and negative antigenic selection in bcl-2 transgenic mice. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[45] D. Vaux,et al. Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[46] S. Korsmeyer,et al. bcl-2-Immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation , 1989, Cell.
[47] P. Krammer,et al. In contrast to effector T cells, CD4+CD25+FoxP3+ regulatory T cells are highly susceptible to CD95 ligand- but not to TCR-mediated cell death. , 2005, Journal of immunology.
[48] J. Casanova,et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy , 2001, Nature Genetics.
[49] H. Chun,et al. Autoimmune lymphoproliferative syndrome: types I, II and beyond. , 2001, Advances in experimental medicine and biology.
[50] M. Bevan,et al. Selecting and maintaining a diverse T-cell repertoire , 1999, Nature.
[51] S. Nagata,et al. Fas and Fas ligand: lpr and gld mutations. , 1995, Immunology today.
[52] J. Merino,et al. Effect of long-term anti-CD4 or anti-CD8 treatment on the development of lpr CD4- CD8- double negative T cells and of the autoimmune syndrome in MRL-lpr/lpr mice. , 1995, Journal of autoimmunity.