A retrospective database study comparing treatment outcomes and cost associated with choice of fixed-dose inhaled corticosteroid/long-acting β2-agonists for asthma maintenance treatment in Germany

Aims:  This retrospective, observational cohort study aimed to compare treatment outcomes and healthcare costs in the year after initiation of maintenance treatment with budesonide/formoterol or salmeterol/fluticasone in a German healthcare setting.

[1]  M. Roth.  Budesonide/Formoterol , 2012, Drugs.

[2]  Wilcox,et al.  HAS ASTHMA CONTROL IMPROVED SINCE AIRE? RESULTS OF A SURVEY IN 5 EUROPEAN COUNTRIES , 2010 .

[3]  G. Guyatt,et al.  The safety of formoterol among patients with asthma using inhaled corticosteroids. Systematic review and meta-analysis. , 2008, Polskie Archiwum Medycyny Wewnetrznej.

[4]  H. Magnussen,et al.  Budesonide/formoterol for maintenance and relief in uncontrolled asthma vs. high-dose salmeterol/fluticasone. , 2007, Respiratory medicine.

[5]  M. Reed,et al.  Scottish Intercollegiate Guidelines Network (SIGN) 84 -- National Clinical Guideline for the Management of Breast Cancer in Women. , 2007, Clinical oncology (Royal College of Radiologists (Great Britain)).

[6]  D. Ryan,et al.  Systematic review and meta-analysis of budesonide/formoterol in a single inhaler , 2007, Current medical research and opinion.

[7]  P. Kuna,et al.  Effect of budesonide/formoterol maintenance and reliever therapy on asthma exacerbations , 2007, International journal of clinical practice.

[8]  P. Gibson,et al.  Differential effects of maintenance long-acting beta-agonist and inhaled corticosteroid on asthma control and asthma exacerbations. , 2007, The Journal of allergy and clinical immunology.

[9]  B. Bender,et al.  Adherence and persistence with fluticasone propionate/salmeterol combination therapy. , 2006, The Journal of allergy and clinical immunology.

[10]  C. Lemière,et al.  Persistence, adherence, and effectiveness of combination therapy among adult patients with asthma. , 2006, The Journal of allergy and clinical immunology.

[11]  A. Chuchalin,et al.  EXCEL: A randomised trial comparing salmeterol/fluticasone propionate and formoterol/budesonide combinations in adults with persistent asthma. , 2006, Respiratory medicine.

[12]  D. Price,et al.  Budesonide/formoterol maintenance and reliever therapy: an effective asthma treatment option? , 2005, European Respiratory Journal.

[13]  J. C. Carranza Rosenzweig,et al.  Adherence to asthma controller medication regimens. , 2005, Respiratory medicine.

[14]  R. Angus,et al.  Short‐acting β2‐agonist and oral corticosteroid use in asthma patients prescribed either concurrent beclomethasone and long‐acting β2‐agonist or salmeterol/fluticasone propionate combination , 2005, International journal of clinical practice.

[15]  P. O'Byrne,et al.  An economic evaluation of combination treatment with budesonide and formoterol in patients with mild-to-moderate persistent asthma. , 2004, Respiratory medicine.

[16]  R. Pauwels,et al.  Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study. , 2004, American journal of respiratory and critical care medicine.

[17]  J. C. Carranza Rosenzweig,et al.  Improved refill persistence with fluticasone propionate and salmeterol in a single inhaler compared with other controller therapies. , 2004, The Journal of allergy and clinical immunology.

[18]  V. Backer,et al.  Adjustable maintenance dosing with budesonide/formoterol compared with fixed-dose salmeterol/fluticasone in moderate to severe asthma , 2004, Current medical research and opinion.

[19]  S. Borg,et al.  Budesonide/formoterol in a single inhaler (Symbicort) reduces healthcare costs compared with separate inhalers in the treatment of asthma over 12 months. , 2003, International journal of clinical practice.

[20]  N. Thomson,et al.  Budesonide and formoterol in a single inhaler improves asthma control compared with increasing the dose of corticosteroid in adults with mild-to-moderate asthma. , 2003, Chest.

[21]  E. Bateman,et al.  Combination Therapy with Single Inhaler Budesonide/Formoterol Compared with High Dose of Fluticasone Propionate Alone in Patients with Moderate Persistent Asthma , 2003, American journal of respiratory medicine : drugs, devices, and other interventions.

[22]  British guideline on the management of asthma. , 2003, Thorax.

[23]  A Tattersfield,et al.  Low dose inhaled budesonide and formoterol in mild persistent asthma: the OPTIMA randomized trial. , 2001, American journal of respiratory and critical care medicine.

[24]  O. Zetterström,et al.  Improved asthma control with budesonide/formoterol in a single inhaler, compared with budesonide alone. , 2001, The European respiratory journal.

[25]  W. Lumry,et al.  Combined Salmeterol 50 μ g and Fluticasone Propionate 250 μ g in the Diskus Device for the Treatment of Asthma , 2000 .

[26]  W. Lumry,et al.  Combined salmeterol 50 microg and fluticasone propionate 250 microg in the diskus device for the treatment of asthma. , 2000, American journal of respiratory and critical care medicine.

[27]  D. Postma,et al.  Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. , 1997, The New England journal of medicine.