Actin cytoskeletal mediators of motility and invasion amplified and overexpressed in head and neck cancer
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[1] M. Kirschner,et al. Erk/Src Phosphorylation of Cortactin Acts as a Switch On-Switch Off Mechanism That Controls Its Ability To Activate N-WASP , 2004, Molecular and Cellular Biology.
[2] K. Zhou,et al. Tyrosine Phosphorylation of Missing in Metastasis Protein Is Implicated in Platelet-derived Growth Factor-mediated Cell Shape Changes* , 2007, Journal of Biological Chemistry.
[3] J. Grandis,et al. Molecular mediators of metastasis in head and neck squamous cell carcinoma. , 2005, Head & neck.
[4] C. J. Barnes,et al. p41‐Arc subunit of human Arp2/3 complex is a p21‐activated kinase‐1‐interacting substrate , 2004, EMBO reports.
[5] M. Tsao,et al. Autotaxin expression in non-small-cell lung cancer. , 1999, American journal of respiratory cell and molecular biology.
[6] K. Belguise,et al. FRA-1 expression level regulates proliferation and invasiveness of breast cancer cells , 2005, Oncogene.
[7] G. Gerisch,et al. Coronin, an actin binding protein of Dictyostelium discoideum localized to cell surface projections, has sequence similarities to G protein beta subunits. , 1991, The EMBO journal.
[8] Y. Onodera,et al. ArfGAP family proteins in cell adhesion, migration and tumor invasion. , 2006, Current opinion in cell biology.
[9] B. Webb,et al. Phosphorylation of cortactin by p21-activated kinase. , 2006, Archives of biochemistry and biophysics.
[10] Y. S. Kim,et al. Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor. , 2001, Cancer research.
[11] C. Lohse,et al. Atypical protein kinase Cι is an oncogene in human non-small cell lung cancer , 2005 .
[12] S. Weed,et al. Cortactin overexpression regulates actin-related protein 2/3 complex activity, motility, and invasion in carcinomas with chromosome 11q13 amplification. , 2006, Cancer research.
[13] Alissa M. Weaver,et al. Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation , 2001, Current Biology.
[14] Liang Cai,et al. Phosphorylation of Coronin 1B by Protein Kinase C Regulates Interaction with Arp2/3 and Cell Motility* , 2005, Journal of Biological Chemistry.
[15] P. Gaffney,et al. Identification of a Gene Expression Signature Associated with Recurrent Disease in Squamous Cell Carcinoma of the Head and Neck , 2004, Cancer Research.
[16] P. Parker,et al. The extended protein kinase C superfamily. , 1998, The Biochemical journal.
[17] J. Reichrath,et al. Different expression patterns of calpain isozymes 1 and 2 (CAPN1 and 2) in squamous cell carcinomas (SCC) and basal cell carcinomas (BCC) of human skin , 2003, The Journal of pathology.
[18] P. Lichter,et al. Recurrent coamplification of cytoskeleton‐associated genes EMS1 and SHANK2 with CCND1 in oral squamous cell carcinoma , 2006, Genes, chromosomes & cancer.
[19] J. Condeelis,et al. Regulation of the actin cytoskeleton in cancer cell migration and invasion. , 2007, Biochimica et biophysica acta.
[20] M. Shi,et al. Phospholipase D Couples Survival and Migration Signals in Stress Response of Human Cancer Cells* , 2006, Journal of Biological Chemistry.
[21] M. Steinmetz,et al. Association of the leukocyte plasma membrane with the actin cytoskeleton through coiled coil-mediated trimeric coronin 1 molecules. , 2005, Molecular biology of the cell.
[22] T. Manabe,et al. Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities , 2005, The EMBO journal.
[23] Suk Woo Nam,et al. Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells , 2000, Oncogene.
[24] Françoise Seillier-Moiseiwitsch,et al. Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function. , 2006, Cancer research.
[25] Erik Sahai,et al. Mechanisms of cancer cell invasion. , 2005, Current opinion in genetics & development.
[26] J. Fox,et al. Calpain Mediates Integrin-induced Signaling at a Point Upstream of Rho Family Members* , 1999, The Journal of Biological Chemistry.
[27] K. Vuori,et al. CAS/Crk Coupling Serves as a “Molecular Switch” for Induction of Cell Migration , 1998, The Journal of cell biology.
[28] K. Pienta,et al. Expression and regulation of MIM (Missing In Metastasis), a novel putative metastasis suppressor gene, and MIM-B, in bladder cancer cell lines. , 2004, Cancer letters.
[29] J. Segall,et al. The great escape: when cancer cells hijack the genes for chemotaxis and motility. , 2005, Annual review of cell and developmental biology.
[30] S. Aizawa,et al. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice , 1995, Nature.
[31] D. Fenyo,et al. Phosphotyrosine Signaling Networks in Epidermal Growth Factor Receptor Overexpressing Squamous Carcinoma Cells*S , 2005, Molecular & Cellular Proteomics.
[32] Alan Wells,et al. Cutting to the chase: calpain proteases in cell motility. , 2002, Trends in cell biology.
[33] N. Colburn,et al. Transactivation of Fra-1 and Consequent Activation of AP-1 Occur Extracellular Signal-Regulated Kinase Dependently , 2002, Molecular and Cellular Biology.
[34] G. Jenkins,et al. Phospholipase D: a lipid centric review , 2005, Cellular and Molecular Life Sciences CMLS.
[35] Min Goo Lee,et al. Shank2 Associates with and Regulates Na+/H+ Exchanger 3* , 2006, Journal of Biological Chemistry.
[36] Anupama E. Gururaj,et al. p21-activated kinases in cancer , 2006, Nature Reviews Cancer.
[37] S. Powers,et al. Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[38] Zhenbao Yu,et al. Functional dissection of human protease μ‐calpain in cell migration using RNAi , 2006, FEBS letters.
[39] S. Franco,et al. Isoform specific function of calpain 2 in regulating membrane protrusion. , 2004, Experimental cell research.
[40] W. Weichert,et al. Protein kinase C isoform expression in ovarian carcinoma correlates with indicators of poor prognosis. , 2003, International journal of oncology.
[41] J. Rodrigo,et al. EMS1 gene amplification correlates with poor prognosis in squamous cell carcinomas of the head and neck. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[42] D. Schlaepfer,et al. Multiple connections link FAK to cell motility and invasion. , 2004, Current opinion in genetics & development.
[43] J. Parsons,et al. pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[44] I. Petersen,et al. Chromosomal alterations during metastasis formation of head and neck squamous cell carcinoma , 2002, Genes, chromosomes & cancer.
[45] Nicole S. Bryce,et al. Cortactin Promotes Cell Motility by Enhancing Lamellipodial Persistence , 2005, Current Biology.
[46] V. Brunton,et al. Advances in Rho-dependent actin regulation and oncogenic transformation. , 2002, Current opinion in genetics & development.
[47] A. Karginov,et al. The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly. , 2002, Molecular biology of the cell.
[48] Anna Huttenlocher,et al. Regulating cell migration: calpains make the cut , 2005, Journal of Cell Science.
[49] J. Bear,et al. Coronins: the return of the crown. , 2006, Trends in cell biology.
[50] I. Petersen,et al. Distinct patterns of chromosomal alterations in high- and low-grade head and neck squamous cell carcinomas. , 1996, Cancer research.
[51] C. R. Leemans,et al. Expression profiling and prediction of distant metastases in head and neck squamous cell carcinoma , 2006, Journal of Clinical Pathology.
[52] Alejandro A Schäffer,et al. Genetic differences detected by comparative genomic hybridization in head and neck squamous cell carcinomas from different tumor sites: construction of oncogenetic trees for tumor progression , 2002, Genes, chromosomes & cancer.
[53] John S. Condeelis,et al. Cofilin Promotes Actin Polymerization and Defines the Direction of Cell Motility , 2004, Science.
[54] Y. Hannun,et al. Protein kinase C isoenzymes: regulation and function. , 1996, Cancer surveys.
[55] K. Nishida,et al. Tyrosine phosphorylation of ACK in response to temperature shift‐down, hyperosmotic shock, and epidermal growth factor stimulation , 1996, FEBS letters.
[56] S. Petersen,et al. Genetic imbalances with impact on survival in head and neck cancer patients. , 2000, The American journal of pathology.
[57] Lijun Xu,et al. Protein Kinase Cι Promotes Nicotine-induced Migration and Invasion of Cancer Cells via Phosphorylation of μ- and m-Calpains* , 2006, Journal of Biological Chemistry.
[58] G. Joberty,et al. The Borgs, a New Family of Cdc42 and TC10 GTPase-Interacting Proteins , 1999, Molecular and Cellular Biology.
[59] L. Liotta,et al. Autotaxin, tumor motility-stimulating exophosphodiesterase. , 1997, Advances in enzyme regulation.
[60] M. Rocchi,et al. Molecular cloning, cDNA sequence, and chromosomal localization of the human phosphatidylinositol 3-kinase p110 alpha (PIK3CA) gene. , 1994, Genomics.
[61] T. Dreyer,et al. Genomic gain of PIK3CA and increased expression of p110alpha are associated with progression of dysplasia into invasive squamous cell carcinoma , 2002, The Journal of pathology.
[62] Hyun Cheol Chung,et al. Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells , 2002, Clinical & Experimental Metastasis.
[63] Kyle J Hewitt,et al. The claudin gene family: expression in normal and neoplastic tissues , 2006, BMC Cancer.
[64] B. Andrews,et al. Direct regulation of Arp2/3 complex activity and function by the actin binding protein coronin , 2002, The Journal of cell biology.
[65] A. Hall,et al. Rac Mediates Cytoskeletal Rearrangements and Increased Cell Motility Induced by Urokinase-Type Plasminogen Activator Receptor Binding to Vitronectin , 2001, The Journal of cell biology.
[66] C. J. Barnes,et al. The Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD1839 (Iressa) Suppresses c-Src and Pak1 Pathways and Invasiveness of Human Cancer Cells , 2004, Clinical Cancer Research.
[67] Yasin Omar,et al. Integrin α2-mediated ERK and Calpain Activation Play a Critical Role in Cell Adhesion and Motility via Focal Adhesion Kinase Signaling , 2006, Journal of Biological Chemistry.
[68] Lijun Xu,et al. Protein kinase Ciota promotes nicotine-induced migration and invasion of cancer cells via phosphorylation of micro- and m-calpains. , 2006, The Journal of biological chemistry.
[69] G. Nemerow,et al. Differential regulation of cell motility and invasion by FAK , 2003, The Journal of cell biology.
[70] O. Bernard,et al. A role for LIM kinase in cancer invasion , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[71] Moshe Talpaz,et al. Dasatinib (BMS-354825) Tyrosine Kinase Inhibitor Suppresses Invasion and Induces Cell Cycle Arrest and Apoptosis of Head and Neck Squamous Cell Carcinoma and Non–Small Cell Lung Cancer Cells , 2005, Clinical Cancer Research.
[72] Wenjun Guo,et al. Integrin signalling during tumour progression , 2004, Nature Reviews Molecular Cell Biology.
[73] C. Haudenschild,et al. Cortactin potentiates bone metastasis of breast cancer cells. , 2001, Cancer research.
[74] Anna Huttenlocher,et al. Calpain-mediated proteolysis of talin regulates adhesion dynamics , 2004, Nature Cell Biology.
[75] E. Avizienyte,et al. Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition. , 2005, Current opinion in cell biology.
[76] L. Kowalski,et al. Overexpression of Fos‐related antigen‐1 in head and neck squamous cell carcinoma , 2005, International journal of experimental pathology.
[77] K. Krapfenbauer,et al. Identification of differentially expressed, tumor‐associated proteins in oral squamous cell carcinoma by proteomic analysis , 2006, Electrophoresis.
[78] G. Borisy,et al. Cell Migration: Integrating Signals from Front to Back , 2003, Science.
[79] C. Lohse,et al. Atypical protein kinase C iota is an oncogene in human non-small cell lung cancer. , 2005, Cancer research.
[80] Kenneth M. Yamada,et al. Tyrosine phosphorylation of the CrkII adaptor protein modulates cell migration , 2003, Journal of Cell Science.
[81] D. Pirone,et al. A New Family of Cdc42 Effector Proteins, CEPs, Function in Fibroblast and Epithelial Cell Shape Changes* , 2001, The Journal of Biological Chemistry.
[82] J. Shah,et al. Molecular cytogenetic characterization of head and neck squamous cell carcinoma and refinement of 3q amplification. , 2001, Cancer research.
[83] S. Ryu,et al. Phospholipase D1 Regulates Cell Migration in a Lipase Activity-independent Manner* , 2006, Journal of Biological Chemistry.
[84] Yu Shyr,et al. Gene Expression Differences Associated with Human Papillomavirus Status in Head and Neck Squamous Cell Carcinoma , 2006, Clinical Cancer Research.
[85] Jeffrey Wyckoff,et al. Cell migration in tumors. , 2005, Current opinion in cell biology.
[86] D. Cantrell. Phosphoinositide 3-kinase signalling pathways. , 2001, Journal of cell science.
[87] Enrique Casado,et al. PI3K/Akt signalling pathway and cancer. , 2004, Cancer treatment reviews.
[88] Carlos Cordon-Cardo,et al. Molecular profiling of tumor progression in head and neck cancer. , 2005, Archives of otolaryngology--head & neck surgery.
[89] J. Chernoff,et al. p21-Activated Kinase 1 (Pak1) Regulates Cell Motility in Mammalian Fibroblasts , 1999, The Journal of cell biology.
[90] M. Busslinger,et al. Transcriptional activation of the fra-1 gene by AP-1 is mediated by regulatory sequences in the first intron , 1995, Molecular and cellular biology.
[91] C. Stournaras,et al. Association of PI-3 kinase with PAK1 leads to actin phosphorylation and cytoskeletal reorganization. , 2002, Molecular biology of the cell.
[92] J. Utikal,et al. The expression of metastasis suppressor MIM/MTSS1 is regulated by DNA methylation , 2006, International journal of cancer.
[93] C. Plass,et al. DNA copy number gains in head and neck squamous cell carcinoma , 2006, Oncogene.
[94] J. Parsons,et al. Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[95] D. Yamazaki,et al. Regulation of cancer cell motility through actin reorganization , 2005, Cancer science.
[96] T. Osaki,et al. Tight junction protein claudin-1 enhances the invasive activity of oral squamous cell carcinoma cells by promoting cleavage of laminin-5 gamma2 chain via matrix metalloproteinase (MMP)-2 and membrane-type MMP-1. , 2006, Cancer research.
[97] A. Wells,et al. Tumor invasion: role of growth factor-induced cell motility. , 2000, Advances in cancer research.
[98] Jonathan A. Cooper,et al. The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[99] J. Schlessinger,et al. Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[100] S. Weed,et al. Cortactin: coupling membrane dynamics to cortical actin assembly , 2001, Oncogene.
[101] P. Verde,et al. Accumulation of Fra-1 in ras-Transformed Cells Depends on Both Transcriptional Autoregulation and MEK-Dependent Posttranslational Stabilization , 2003, Molecular and Cellular Biology.
[102] J. Colicelli,et al. RIN1 Is an ABL Tyrosine Kinase Activator and a Regulator of Epithelial-Cell Adhesion and Migration , 2005, Current Biology.
[103] S. Tsukita,et al. Pores in the Wall , 2000, The Journal of cell biology.
[104] T. Boeckers,et al. ProSAP/Shank proteins – a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease , 2002, Journal of neurochemistry.
[105] L. Lim,et al. Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas , 1999, Nature Cell Biology.
[106] D. Hirsch,et al. Arf GAPs: multifunctional proteins that regulate membrane traffic and actin remodelling. , 2004, Cellular signalling.
[107] M. Schaller,et al. FAK regulates biological processes important for the pathogenesis of cancer , 2003, Cancer and Metastasis Reviews.
[108] N. Yang,et al. Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma. , 2006, Cancer research.
[109] M. Sheng,et al. Sharpin, a Novel Postsynaptic Density Protein That Directly Interacts with the Shank Family of Proteins , 2001, Molecular and Cellular Neuroscience.
[110] M. Ashburner,et al. Gene Ontology: tool for the unification of biology , 2000, Nature Genetics.
[111] M. Martinelli,et al. Microarray analysis and RNA silencing link fra-1 to cd44 and c-met expression in mesothelioma. , 2003, Cancer research.
[112] Yasuyuki Shima,et al. Differential activities, subcellular distribution and tissue expression patterns of three members of Slingshot family phosphatases that dephosphorylate cofilin , 2003, Genes to cells : devoted to molecular & cellular mechanisms.
[113] Claudia Castaldi,et al. Dynamin participates in focal extracellular matrix degradation by invasive cells. , 2003, Molecular biology of the cell.
[114] N. Colburn,et al. Fra-1 a target for cancer prevention or intervention. , 2006, Gene.
[115] K. Pienta,et al. Differential expression analysis of MIM (MTSS1) splice variants and a functional role of MIM in prostate cancer cell biology. , 2005, International Journal of Oncology.
[116] D. Noh,et al. Overexpression of phospholipase D1 in human breast cancer tissues. , 2000, Cancer letters.
[117] Neil O. Carragher,et al. The role of focal-adhesion kinase in cancer — a new therapeutic opportunity , 2005, Nature Reviews Cancer.
[118] L. Liotta,et al. Stimulation of Tumor Cell Motility Linked to Phosphodiesterase Catalytic Site of Autotaxin* , 1996, The Journal of Biological Chemistry.
[119] H. Hosaka,et al. Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[120] András Kapus,et al. Cortactin: the gray eminence of the cytoskeleton. , 2006, Physiology.
[121] T. Kwon,et al. Transmodulation between Phospholipase D and c-Src Enhances Cell Proliferation , 2003, Molecular and Cellular Biology.
[122] Masahiko Watanabe,et al. Lysophosphatidic Acid and Autotaxin Stimulate Cell Motility of Neoplastic and Non-neoplastic Cells through LPA1* , 2004, Journal of Biological Chemistry.
[123] T. Uemura,et al. Control of Actin Reorganization by Slingshot, a Family of Phosphatases that Dephosphorylate ADF/Cofilin , 2002, Cell.
[124] F. P. Finger. One ring to bind them. Septins and actin assembly. , 2002, Developmental cell.
[125] T. Haystead,et al. Borg proteins control septin organization and are negatively regulated by Cdc42 , 2001, Nature Cell Biology.
[126] Alissa M. Weaver,et al. Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia. , 2007, Cancer research.
[127] C. Perou,et al. Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression. , 2004, Cancer cell.
[128] D. Roymans,et al. Phosphatidylinositol 3-kinases in tumor progression. , 2001, European journal of biochemistry.
[129] G. Mills,et al. Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production , 2002, The Journal of cell biology.
[130] T. Godfrey,et al. Comprehensive genome and transcriptome analysis of the 11q13 amplicon in human oral cancer and synteny to the 7F5 amplicon in murine oral carcinoma , 2006, Genes, chromosomes & cancer.
[131] J. Segall,et al. Specific Requirement for the p85-p110α Phosphatidylinositol 3-Kinase during Epidermal Growth Factor-stimulated Actin Nucleation in Breast Cancer Cells* , 2000, The Journal of Biological Chemistry.
[132] Hans van Dam,et al. Distinct roles of Jun : Fos and Jun : ATF dimers in oncogenesis , 2001, Oncogene.
[133] Bob van de Water,et al. Focal adhesion kinase: a potential target in cancer therapy. , 2007, Biochemical pharmacology.
[134] Timothy Y. Huang,et al. Cofilin phosphatases and regulation of actin dynamics. , 2006, Current opinion in cell biology.
[135] D. C. Edwards,et al. Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics , 1999, Nature Cell Biology.
[136] J. Shah,et al. Amplification of the 3q26.3 locus is associated with progression to invasive cancer and is a negative prognostic factor in head and neck squamous cell carcinomas. , 2002, The American journal of pathology.
[137] L. Liotta,et al. Autotaxin Is an Exoenzyme Possessing 5′-Nucleotide Phosphodiesterase/ATP Pyrophosphatase and ATPase Activities* , 1997, The Journal of Biological Chemistry.
[138] P. Friedl,et al. The biology of cell locomotion within three-dimensional extracellular matrix , 2000, Cellular and Molecular Life Sciences CMLS.
[139] E. Sabo,et al. Claudin-1 is a strong prognostic indicator in stage II colonic cancer: a tissue microarray study , 2005, Modern Pathology.
[140] J. Condeelis,et al. Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation , 2004, The Journal of cell biology.
[141] L. Machesky,et al. MIM: a multifunctional scaffold protein , 2007, Journal of Molecular Medicine.
[142] N. Smith,et al. Differential regulation of cortactin and N-WASP-mediated actin polymerization by missing in metastasis (MIM) protein , 2005, Oncogene.
[143] T. Pollard,et al. Cellular Motility Driven by Assembly and Disassembly of Actin Filaments , 2003, Cell.
[144] James L Mohler,et al. Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox. , 2005, Cancer research.
[145] W. Miller,et al. Phosphorylation of WASP by the Cdc42-associated Kinase ACK1 , 2005, Journal of Biological Chemistry.
[146] Dihua Yu,et al. Heregulin β1-activated Phosphatidylinositol 3-Kinase Enhances Aggregation of MCF-7 Breast Cancer Cells Independent of Extracellular Signal-regulated Kinase , 1999 .
[147] J. Condeelis,et al. Initiation of cofilin activity in response to EGF is uncoupled from cofilin phosphorylation and dephosphorylation in carcinoma cells , 2006, Journal of Cell Science.
[148] M. L. Le Beau,et al. A consistent pattern of RIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage‐fusion‐bridge cycle model for 11q13 amplification , 2000, Genes, chromosomes & cancer.
[149] J. Segall,et al. Molecular mechanisms of invadopodium formation , 2005, The Journal of cell biology.
[150] D. Yu,et al. Heregulin beta1-activated phosphatidylinositol 3-kinase enhances aggregation of MCF-7 breast cancer cells independent of extracellular signal-regulated kinase. , 1999, Cancer research.
[151] Y. Kaziro,et al. Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation. , 2000, Biochemical and biophysical research communications.
[152] R. Kramer,et al. Tumor cell invasion and survival in head and neck cancer , 2005, Cancer and Metastasis Reviews.
[153] L. Machesky,et al. Involvement of Rac in actin cytoskeleton rearrangements induced by MIM-B , 2005, Journal of Cell Science.
[154] Osamu Ohmori,et al. A novel low‐molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth , 2007, Molecular carcinogenesis.
[155] A. Herrero,et al. Overexpression of Focal Adhesion Kinase in Head and Neck Squamous Cell Carcinoma Is Independent of fak Gene Copy Number , 2006, Clinical Cancer Research.
[156] P. Morin,et al. Claudin proteins in human cancer: promising new targets for diagnosis and therapy. , 2005, Cancer research.
[157] Jonathan A. Cooper,et al. ASAP1, a Phospholipid-Dependent Arf GTPase-Activating Protein That Associates with and Is Phosphorylated by Src , 1998, Molecular and Cellular Biology.
[158] T. Stossel,et al. Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1 , 2002, Nature Cell Biology.
[159] L. Lim,et al. A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42 , 1993, Nature.
[160] L. Lim,et al. A brain serine/threonine protein kinase activated by Cdc42 and Rac1 , 1994, Nature.
[161] Kenneth J Pienta,et al. MIM, a potential metastasis suppressor gene in bladder cancer. , 2002, Neoplasia.
[162] R. Vallee,et al. Dynamin Isoform-specific Interaction with the Shank/ProSAP Scaffolding Proteins of the Postsynaptic Density and Actin Cytoskeleton* , 2001, The Journal of Biological Chemistry.
[163] Xiaoping Du,et al. Evidence That β3 Integrin-Induced Rac Activation Involves the Calpain-Dependent Formation of Integrin Clusters That Are Distinct from the Focal Complexes and Focal Adhesions That Form as Rac and Rhoa Become Active , 2000, The Journal of cell biology.
[164] J. Greenman,et al. Unraveling the Chromosomal Aberrations of Head and Neck Squamous Cell Carcinoma: A Review , 2005, Annals of Surgical Oncology.
[165] E. Schuuring. The involvement of the chromosome 11q13 region in human malignancies: cyclin D1 and EMS1 are two new candidate oncogenes--a review. , 1995, Gene.
[166] S. Weed,et al. Identification of a Novel Cortactin SH3 Domain-Binding Protein and Its Localization to Growth Cones of Cultured Neurons , 1998, Molecular and Cellular Biology.
[167] A. Chow,et al. Intracellular signaling by phospholipase D as a therapeutic target. , 2001, Current pharmaceutical biotechnology.
[168] J. Shah,et al. The role of novel oncogenes squamous cell carcinoma-related oncogene and phosphatidylinositol 3-kinase p110alpha in squamous cell carcinoma of the oral tongue. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[169] E. Sahai,et al. ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility. , 2003, Cancer cell.
[170] Liang Cai,et al. Coronin 1B Coordinates Arp2/3 Complex and Cofilin Activities at the Leading Edge , 2007, Cell.
[171] S. Gollin. Chromosomal alterations in squamous cell carcinomas of the head and neck: Window to the biology of disease , 2001, Head & neck.
[172] B. Venkatesh,et al. The RIN family of Ras effectors. , 2006, Methods in enzymology.
[173] Christopher Autry,et al. Cellular Characterization of a Novel Focal Adhesion Kinase Inhibitor* , 2007, Journal of Biological Chemistry.
[174] G. Bokoch,et al. Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells , 1997, Current Biology.
[175] Crislyn D'Souza-Schorey,et al. ARF proteins: roles in membrane traffic and beyond , 2006, Nature Reviews Molecular Cell Biology.
[176] J. Gruschus,et al. Phosphoinositide-dependent Activation of the ADP-ribosylation Factor GTPase-activating Protein ASAP1 , 2000, The Journal of Biological Chemistry.
[177] R. Klemke,et al. Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold. , 2004, Biochimica et biophysica acta.
[178] Scott N. Boyle,et al. A Critical Role for Cortactin Phosphorylation by Abl-Family Kinases in PDGF-Induced Dorsal-Wave Formation , 2007, Current Biology.
[179] Rebecca Slack,et al. Co-localization of cortactin and phosphotyrosine identifies active invadopodia in human breast cancer cells. , 2006, Experimental cell research.
[180] S. Kamel‐Reid,et al. Molecular cytogenetic analysis of head and neck squamous cell carcinoma: By comparative genomic hybridization, spectral karyotyping, and expression array analysis , 2002, Head & neck.