Haemato-biochemical changes and efficacy of different acaricides in crossbred animals

Haematological and biochemical changes were evaluated in naturally tick infested crossbred cattle based on the treatment with 3 different acaricides. viz. ivermectin, amitraz and pestoban. Haematological examination revealed a significant (P<0.01) reduction in Hb, PCV, TEC and TLC in tick infested groups (2, 3 and 4) as compared to control group (group 1). There was no significant (P<0.05) changes in MCV, MCH anti MCHC while the eosinophil count was significantly high (P<0.01) in tick infested groups than lymphocytes, neutrophils, and manocytes. Biochemical analysis revealed a significant (P<0.01) decrease in total serum protein, albumin but nonsignificant difference in globulin and albumin: globulin ratio. The efficacies of ivermectin, amitraz and pestoban were evaluated on the basis of ixodicidal activity and improvement in haemato-biochemical values where ivermectin treated group (group 2) showed higher efficacy against ticks and faster improvement in haemato-biochemical changes.