Age-dependent deficiency in saliva and salivary antibodies secretion in Down's syndrome.

[1]  T. Modéer,et al.  Oral carriage of Candida species in children and adolescents with Down's syndrome. , 2009, International journal of paediatric dentistry.

[2]  Rafat Hussain,et al.  The four ages of Down syndrome. , 2007, European journal of public health.

[3]  Z. Bian,et al.  Protective efficacy of a targeted anti-caries DNA plasmid against cariogenic bacteria infections. , 2007, Vaccine.

[4]  J. Merrick,et al.  Salivary LL-37 Secretion in Individuals with Down Syndrome is Normal , 2006, Journal of dental research.

[5]  E. Yefenof,et al.  The outcome of a preventive dental care programme on the prevalence of localized aggressive periodontitis in Down's syndrome individuals. , 2006, Journal of intellectual disability research : JIDR.

[6]  K. Sayama,et al.  Susceptibilities of periodontopathogenic and cariogenic bacteria to antibacterial peptides, {beta}-defensins and LL37, produced by human epithelial cells. , 2005, The Journal of antimicrobial chemotherapy.

[7]  D. Sakellari,et al.  Periodontal conditions and subgingival microflora in Down syndrome patients. A case-control study. , 2005, Journal of clinical periodontology.

[8]  S. Michalek,et al.  A Caries Vaccine? , 2004, Caries Research.

[9]  S. Michalek,et al.  Effect of age on immunoglobulin A subclass distribution in human parotid saliva. , 2003, Oral microbiology and immunology.

[10]  M. Navazesh.  How can oral health care providers determine if patients have dry mouth? , 2003, Journal of the American Dental Association.

[11]  A. Becker,et al.  Parotid salivary immunoglobulins, recurrent respiratory tract infections and gingival health in institutionalized and non-institutionalized subjects with Down's syndrome. , 2003, Journal of intellectual disability research : JIDR.

[12]  W. Siqueira,et al.  Stimulated whole saliva components in children with Down syndrome. , 2002, Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry.

[13]  M. Zasloff.  Innate immunity, antimicrobial peptides, and protection of the oral cavity , 2002, The Lancet.

[14]  Göran Carlsson,et al.  Deficiency of antibacterial peptides in patients with morbus Kostmann: an observation study , 2002, The Lancet.

[15]  E. Yefenof,et al.  Severe Impairment of Secretory Ig Production in Parotid Saliva of Down Syndrome Individuals , 2002, Journal of dental research.

[16]  A. V. van Winkelhoff,et al.  Absence of a specific subgingival microflora in adults with Down's syndrome. , 2001, Journal of clinical periodontology.

[17]  R. Russell,et al.  Effect of age on the gastrointestinal-associated mucosal immune response of humans. , 2001, The journals of gerontology. Series A, Biological sciences and medical sciences.

[18]  S. Hamada,et al.  Periodontopathic bacteria in children with Down syndrome. , 2000, Journal of periodontology.

[19]  S. Akyüz,et al.  Salivary sialic acid, protein, salivary flow rate, pH, buffering capacity and caries indices in subjects with Down's syndrome. , 1999, Journal of dentistry.

[20]  J. Tenovuo,et al.  Antimicrobial function of human saliva--how important is it for oral health? , 1998, Acta odontologica Scandinavica.

[21]  P. Cichoń,et al.  Early-onset periodontitis associated with Down's syndrome--clinical interventional study. , 1998, Annals of periodontology.

[22]  S. Michalek,et al.  Effect of immune T cells derived from mucosal or systemic tissue on host responses to Porphyromonas gingivalis. , 1998, Oral microbiology and immunology.

[23]  H. Marcotte,et al.  Oral Microbial Ecology and the Role of Salivary Immunoglobulin A , 1998, Microbiology and Molecular Biology Reviews.

[24]  S. Desai.  Down syndrome: a review of the literature. , 1997, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[25]  P. Marsh,et al.  Age-related changes in salivary antibodies to commensal oral and gut biota. , 1997, Oral microbiology and immunology.

[26]  A. N. Nieuw Amerongen,et al.  Analysis of the concentration and output of whole salivary constituents in patients with Sjögren's syndrome. , 1996, European journal of oral sciences.

[27]  A. Vissink,et al.  Aging and saliva: a review of the literature. , 1996, Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry.

[28]  P D Marsh,et al.  Age-related changes in immunoglobulin isotypes in whole and parotid saliva and serum in healthy individuals. , 1995, Oral microbiology and immunology.

[29]  A. V. van Winkelhoff,et al.  Short-term effect of full-mouth extraction on periodontal pathogens colonizing the oral mucous membranes. , 1994, Journal of clinical periodontology.

[30]  P. Marsh,et al.  Flow Rates of Resting Whole and Stimulated Parotid Saliva in Relation to Age and Gender , 1994, Journal of dental research.

[31]  K. Schenck,et al.  Levels of salivary IgA antibodies reactive with bacteria from dental plaque are associated with susceptibility to experimental gingivitis. , 1993, Journal of clinical periodontology.

[32]  L. Hammarström,et al.  Oral conditions in individuals with selective immunoglobulin A deficiency and common variable immunodeficiency. , 1992, Journal of periodontology.

[33]  T. Modéer,et al.  Actinobacillus actinomycetemcomitans, Capnocytophaga and Porphyromonas gingivalis in subgingival plaque of adolescents with Down's syndrome. , 1992, Oral microbiology and immunology.

[34]  J. Barton,et al.  Immunosenescence and mucosal immunity: significant effects of old age on secretory IgA concentrations and intraepithelial lymphocyte counts. , 1992, Gut.

[35]  M. Sela,et al.  Caries levels, Streptococcus mutans counts, salivary pH, and periodontal treatment needs of adult Down syndrome patients. , 1991, Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry.

[36]  J. Sterne,et al.  Detection of high-risk groups and individuals for periodontal diseases: laboratory markers from analysis of saliva. , 1989, Journal of clinical periodontology.

[37]  C. Tylenda,et al.  Evaluation of Submandibular Salivary Flow Rate in Different Age Groups , 1988, Journal of dental research.

[38]  G. Lockitch,et al.  Age-Related Changes in Humoral and Cell- Mediated Immunity in Down Syndrome Children Living at Home , 1987, Pediatric Research.

[39]  W. Loesche.  Role of Streptococcus mutans in human dental decay. , 1986, Microbiological reviews.

[40]  M. Saxby,et al.  Periodontal destruction in Down's syndrome and in juvenile periodontitis. How close a similarity? , 1986, Journal of periodontology.

[41]  W. E. Wright,et al.  Therapy-induced dysfunction of salivary glands: implications for oral health. , 1985, Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry.

[42]  B. J. Baum,et al.  Basic Biological Sciences Unstimulated and Stimulated Parotid Salivary Flow Rate in Individuals of Different Ages , 1984, Journal of dental research.

[43]  J. Slots.  Selective medium for isolation of Actinobacillus actinomycetemcomitans , 1982, Journal of clinical microbiology.

[44]  L. Saxén,et al.  Periodontal bone loss in patients with Down's syndrome: a follow-up study. , 1982, Journal of periodontology.

[45]  B. J. Baum,et al.  Clinical Science , 1981 .

[46]  P. Robertson,et al.  Periodontal status of patients with abnormalities of the immune system. II. Observations over a 2-year period. , 1980, Journal of periodontology.

[47]  J. Zamet.  Book Review: The Borderland between Caries and Periodontal Disease , 1978 .

[48]  P. Brandtzaeg.  Synthesis and Secretion of Secretory Immunoglobulins: With Special Reference to Dental Diseases , 1976, Journal of dental research.

[49]  G. Orner.  Dental caries experience among children with Down's syndrome and their sibs. , 1975, Archives of oral biology.

[50]  T. Cutress.  Dental caries in trisomy 21. , 1971, Archives of oral biology.

[51]  H. Chauncey,et al.  Composition of Human Saliva, Parotid Gland Secretory Rate, and Electrolyte Concentration in Mentally Subnormal Persons , 1965, Journal of dental research.

[52]  N. Kutukculer,et al.  Evaluation of the relationship between caries indices and salivary secretory IgA, salivary pH, buffering capacity and flow rate in children with Down's syndrome. , 2006, Archives of oral biology.

[53]  A. Becker,et al.  Stimulated parotid salivary flow rate in patients with Down syndrome. , 2002, Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry.

[54]  Y Abiko,et al.  Passive immunization against dental caries and periodontal disease: development of recombinant and human monoclonal antibodies. , 2000, Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists.

[55]  A. Wu,et al.  Extended stimulated parotid and submandibular secretion in a healthy young and old population. , 1995, The journals of gerontology. Series A, Biological sciences and medical sciences.

[56]  G. Dahlén,et al.  Periodontal disease and dental caries in relation to primary IgG subclass and other humoral immunodeficiencies. , 1993, Journal of clinical periodontology.

[57]  L. Jara,et al.  Composition of the parotid saliva in Chilean children with Down's syndrome. , 1991, Archivos de biologia y medicina experimentales.

[58]  N. Johnson,et al.  Detection of high-risk groups and individuals for periodontal diseases. , 1989, International dental journal.

[59]  A. Ugazio,et al.  Down's syndrome: problems of immunodeficiency. , 1981, Human genetics. Supplement.