论文信息 - X-Ray crystallographic analysis of 2,6-anhydro-N-methyl-D-glycero-D-ido-heptonamide: the first example of a simple glucose analogue with a skew boat structure

X-Ray crystallographic analysis of 2,6-anhydro-N-methyl-D-glycero-D-ido-heptonamide: the first example of a simple glucose analogue with a skew boat structure

Single crystal X-ray crystallographic analysis of 2,6-anhydro-N-methyl-D-glycero-D-ido-heptonamide and a crystallographic binding study with glycogen phosphorylase show an unexpected skew boat conformation for the glucose analogue.

[1] J. Hajdu,et al. Channels at the catalytic site of glycogen phosphorylase b: binding and kinetic studies with the beta-glycosidase inhibitor D-gluconohydroximo-1,5-lactone N-phenylurethane. , 1988, Biochemistry.

[2] L. Johnson,et al. Crystallization of pig skeletal phosphorylase b. Purification, physical and catalytic characterization. , 1985, Biochimica et biophysica acta.

[3] H. A. Levy,et al. α-d-Glucose: further refinement based on neutron-diffraction data , 1979 .

[4] R. Lemieux,et al. The conformational properties of glycosidic linkages , 1974 .