Characterisation of recombinant hyaluronidase-1 and -3, and of hyaluronan turnover in mineralising osteoblasts.

[1]  D. Scharnweber,et al.  Increased bone formation around coated implants. , 2009, Journal of clinical periodontology.

[2]  K. Römisch.  Endoplasmic reticulum-associated degradation. , 2005, Annual review of cell and developmental biology.

[3]  F. Wurm.  Production of recombinant protein therapeutics in cultivated mammalian cells , 2004, Nature Biotechnology.

[4]  C. Handley,et al.  Large aggregating and small leucine-rich proteoglycans are degraded by different pathways and at different rates in tendon. , 2004, European journal of biochemistry.

[5]  R. Stern.  Devising a pathway for hyaluronan catabolism: are we there yet? , 2003, Glycobiology.

[6]  Alan J Dickson,et al.  Stability of protein production from recombinant mammalian cells , 2003, Biotechnology and bioengineering.

[7]  M. Soloway,et al.  Regulation of Hyaluronidase Activity by Alternative mRNA Splicing* , 2002, The Journal of Biological Chemistry.

[8]  A Boyde,et al.  Phenotypic Effects of Biglycan Deficiency Are Linked to Collagen Fibril Abnormalities, Are Synergized by Decorin Deficiency, and Mimic Ehlers‐Danlos‐Like Changes in Bone and Other Connective Tissues , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[9]  J. McDonald,et al.  Hyaluronan: Genetic insights into the complex biology of a simple polysaccharide , 2002, Glycoconjugate Journal.

[10]  S. Reitinger,et al.  Xenopus kidney hyaluronidase‐1 (XKH1), a novel type of membrane‐bound hyaluronidase solely degrades hyaluronan at neutral pH1 , 2001, FEBS letters.

[11]  E. Meese,et al.  Identification of a nuclear variant of MGEA5, a cytoplasmic hyaluronidase and a beta-N-acetylglucosaminidase. , 2001, Biochemical and biophysical research communications.

[12]  M. Barnett,et al.  Glycosaminoglycans in the study of mammalian organ development. , 2001, Biochemical Society transactions.

[13]  F. Duh,et al.  Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[14]  J. Weissenbach,et al.  Perlecan, the major proteoglycan of basement membranes, is altered in patients with Schwartz-Jampel syndrome (chondrodystrophic myotonia) , 2000, Nature Genetics.

[15]  A. Spicer,et al.  Hyaluronan: a multifunctional, megaDalton, stealth molecule. , 2000, Current opinion in cell biology.

[16]  P. Rizkallah,et al.  Crystal structure of hyaluronidase, a major allergen of bee venom. , 2000, Structure.

[17]  B. Hoflack,et al.  Bi-directional trafficking between the trans-Golgi network and the endosomal/lysosomal system. , 2000, Journal of cell science.

[18]  B. Hoflack,et al.  Targeting of lysosomal proteins. , 2000, Seminars in cell & developmental biology.

[19]  S. Selleck.  Proteoglycans and pattern formation: sugar biochemistry meets developmental genetics. , 2000, Trends in genetics : TIG.

[20]  J. Small,et al.  Hyaluronic Acid (Ha) Binding to Cd44 Activates Rac1 and Induces Lamellipodia Outgrowth , 2000, The Journal of cell biology.

[21]  P. Heldin,et al.  Expression of recombinant hyaluronan synthase (HAS) isoforms in CHO cells reduces cell migration and cell surface CD44. , 1999, Experimental cell research.

[22]  S. Scherer,et al.  Expression analysis of six paralogous human hyaluronidase genes clustered on chromosomes 3p21 and 7q31. , 1999, Genomics.

[23]  P. Lenas,et al.  Three Isoforms of Mammalian Hyaluronan Synthases Have Distinct Enzymatic Properties* , 1999, The Journal of Biological Chemistry.

[24]  R. Old,et al.  Expression pattern of a novel hyaluronidase during Xenopus embryogenesis , 1999, Mechanisms of Development.

[25]  J. Esko,et al.  Molecular Cloning and Expression of a Third Member of the Heparan Sulfate/Heparin GlcNAcN-Deacetylase/ N-Sulfotransferase Family* , 1999, The Journal of Biological Chemistry.

[26]  E. Turley,et al.  Rapid hyaluronan uptake is associated with enhanced motility: implications for an intracellular mode of action , 1998, FEBS letters.

[27]  L. Schaefer,et al.  Decorin, biglycan and their endocytosis receptor in rat renal cortex. , 1998, Kidney international.

[28]  C. Little,et al.  Expression and activity of articular cartilage hyaluronidases. , 1998, Biochemical and biophysical research communications.

[29]  S. Goldstein,et al.  Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice , 1998, Nature Genetics.

[30]  G. Karsenty.  Transcriptional regulation of osteoblast differentiation during development. , 1998, Frontiers in bioscience : a journal and virtual library.

[31]  B. Hogan,et al.  Altered wound healing in mice lacking a functional osteopontin gene (spp1). , 1998, The Journal of clinical investigation.

[32]  J. Sanes,et al.  Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age‐onset cataract formation and disruption of the lens , 1998, The EMBO journal.

[33]  J. McDonald,et al.  Characterization and Molecular Evolution of a Vertebrate Hyaluronan Synthase Gene Family* , 1998, The Journal of Biological Chemistry.

[34]  A. I. Yudin,et al.  Biochemical characterization of the PH‐20 protein on the plasma membrane and inner acrosomal membrane of cynomolgus macaque spermatozoa , 1997, Molecular reproduction and development.

[35]  A. Freemont,et al.  Early‐response gene signalling is induced by angiogenic oligosaccharides of hyaluronan in endothelial cells. Inhibition by non‐angiogenic, high‐molecular‐weight hyaluronan , 1997, International journal of cancer.

[36]  G. Hart,et al.  Dynamic Glycosylation of Nuclear and Cytosolic Proteins , 1997, The Journal of Biological Chemistry.

[37]  J. Hassell,et al.  Identification of Sites in Domain I of Perlecan That Regulate Heparan Sulfate Synthesis* , 1997, The Journal of Biological Chemistry.

[38]  B. Wilkinson,et al.  Protein Translocation Across the Membrane of the Endoplasmic Reticulum , 1997, The Journal of Membrane Biology.

[39]  V. Hascall,et al.  Coding sequence of a hyaluronan synthase homologue expressed during expansion of the mouse cumulus-oocyte complex. , 1997, Archives of biochemistry and biophysics.

[40]  M. Gebhardt,et al.  Clinical and biochemical manifestations of hyaluronidase deficiency. , 1996, The New England journal of medicine.

[41]  J. Willson,et al.  Expression of hyaluronidase by tumor cells induces angiogenesis in vivo. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[42]  G. Hunnicutt,et al.  Sperm surface protein PH-20 is bifunctional: one activity is a hyaluronidase and a second, distinct activity is required in secondary sperm-zona binding. , 1996, Biology of reproduction.

[43]  R. Rudolph,et al.  The effect of molecular chaperones on in vivo and in vitro folding processes. , 1996, Biological chemistry.

[44]  R. Midura,et al.  Spatial distribution of CD44 and hyaluronan in the proximal tibia of the growing rat , 1996, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[45]  H. Geuze,et al.  Intracellular trafficking of lysosomal membrane proteins , 1996, BioEssays : news and reviews in molecular, cellular and developmental biology.

[46]  J. Esko,et al.  Repetitive Ser-Gly Sequences Enhance Heparan Sulfate Assembly in Proteoglycans (*) , 1995, The Journal of Biological Chemistry.

[47]  M. Jones,et al.  Expression analysis, genomic structure, and mapping to 7q31 of the human sperm adhesion molecule gene SPAM1. , 1995, Genomics.

[48]  H. M. Kim,et al.  Structural and chemical characteristics and maturation of the calcium‐phosphate crystals formed during the calcification of the organic matrix synthesized by chicken osteoblasts in cell culture , 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[49]  H. Anderson.  Molecular biology of matrix vesicles. , 1995, Clinical orthopaedics and related research.

[50]  S. Yamagata,et al.  Analysis of glycosaminoglycan-degrading enzymes by substrate gel electrophoresis (zymography). , 1995, Analytical biochemistry.

[51]  S. Withers,et al.  Approaches to labeling and identification of active site residues in glycosidases , 1995, Protein science : a publication of the Protein Society.

[52]  D. Heinegård,et al.  The cartilage proteoglycan aggregate: assembly through combined protein-carbohydrate and protein-protein interactions. , 1994, Biophysical chemistry.

[53]  S. Sagan,et al.  The human sperm protein PH‐20 has hyaluronidase activity , 1993, FEBS letters.

[54]  N. Sharon,et al.  Protein glycosylation. Structural and functional aspects. , 1993, European journal of biochemistry.

[55]  G. Hunter,et al.  Nucleation of hydroxyapatite by bone sialoprotein. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[56]  A Bairoch,et al.  New families in the classification of glycosyl hydrolases based on amino acid sequence similarities. , 1993, The Biochemical journal.

[57]  G. Kreil,et al.  Bee venom hyaluronidase is homologous to a membrane protein of mammalian sperm. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[58]  B. Spooner,et al.  Embryonic lung morphogenesis in organ culture: experimental evidence for a proteoglycan function in the extracellular matrix. , 1993, Transactions of the Kansas Academy of Science. Kansas Academy of Science.

[59]  L. Bonewald,et al.  Effects of combining transforming growth factor beta and 1,25-dihydroxyvitamin D3 on differentiation of a human osteosarcoma (MG-63). , 1992, The Journal of biological chemistry.

[60]  J. Fransen,et al.  Mannose 6-phosphate receptor independent targeting of lysosomal enzymes (a mini-review). , 1991, Cell biology international reports.

[61]  P. de Waard,et al.  Structural studies on sulfated oligosaccharides derived from the carbohydrate-protein linkage region of chondroitin sulfate proteoglycans of whale cartilage. , 1991, European journal of biochemistry.

[62]  D A Cumming,et al.  Glycosylation of recombinant protein therapeutics: control and functional implications. , 1991, Glycobiology.

[63]  T. Ji,et al.  Differential interactions of human choriogonadotropin and its antagonistic aglycosylated analog with their receptor. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[64]  R. Midura,et al.  A rat osteogenic cell line (UMR 106-01) synthesizes a highly sulfated form of bone sialoprotein. , 1990, The Journal of biological chemistry.

[65]  D. Feingold,et al.  Biosynthesis of heparin. Modulation of polysaccharide chain length in a cell-free system. , 1988, The Biochemical journal.

[66]  P. de Waard,et al.  Structural studies on sulfated glycopeptides from the carbohydrate-protein linkage region of chondroitin 4-sulfate proteoglycans of swarm rat chondrosarcoma. Demonstration of the structure Gal(4-O-sulfate)beta 1-3Gal beta 1-4XYL beta 1-O-Ser. , 1988, The Journal of biological chemistry.

[67]  A. S. Posner.  The Mineral of Bone , 1985, Clinical orthopaedics and related research.

[68]  A. Boskey,et al.  Mechanisms of proteoglycan inhibition of hydroxyapatite growth , 1985, Calcified Tissue International.

[69]  I. Hampson,et al.  Angiogenesis induced by degradation products of hyaluronic acid. , 1985, Science.

[70]  T. Schmid,et al.  Selective hydrolysis of chondroitin sulfates by hyaluronidase. , 1984, Biochemistry.

[71]  A. Reddi.  Cell biology and biochemistry of endochondral bone development. , 1981, Collagen and related research.

[72]  S. Okada,et al.  Amino acid composition and physiochemical characterization of chondroitinase from Arthrobacter aurescens. , 1975, Journal of biochemistry.

[73]  M. Seligman,et al.  Mineralization of elastin extracted from human aortic tissues , 1975, Calcified Tissue Research.

[74]  H. C. Robinson,et al.  The alkali-labile linkage between keratan sulphate and protein. , 1974, The Biochemical journal.

[75]  N. Blumenkrantz,et al.  New method for quantitative determination of uronic acids. , 1973, Analytical biochemistry.

[76]  S. Pallante,et al.  Complexes of organic acids with calcium phosphate: the von Kossa stain as a clue to the composition of bone mineral. , 1971, The Johns Hopkins medical journal.

[77]  A. Linker,et al.  The Hyaluronidase of the Leech: an Endoglucuronidase , 1957, Nature.

[78]  F. O. Schmitt,et al.  MACROMOLECULAR AGGREGATION STATES IN RELATION TO MINERALIZATION: THE COLLAGEN-HYDROXYAPATITE SYSTEM AS STUDIED IN VITRO. , 1957, Proceedings of the National Academy of Sciences of the United States of America.

[79]  J. Adams,et al.  Expression of hyaluronan synthases and hyaluronidases in the MG63 osteoblast cell line. , 2006, Matrix biology : journal of the International Society for Matrix Biology.

[80]  A. Young.  Effects on bone. , 2005, Advances in pharmacology.

[81]  G. Embery,et al.  Molecular interaction of recombinant decorin and biglycan with type I collagen influences crystal growth. , 2003, Connective tissue research.

[82]  S. Cowan-Jacob,et al.  Snags with tags : Some observations made with ( His ) 6-tagged proteins , 2002 .

[83]  J. Funderburgh.  Keratan sulfate: structure, biosynthesis, and function. , 2000, Glycobiology.

[84]  A. J. Parodi,et al.  Protein glucosylation and its role in protein folding. , 2000, Annual review of biochemistry.

[85]  G. Embery,et al.  Calcium- and hydroxyapatite-binding properties of glucuronic acid-rich and iduronic acid-rich glycosaminoglycans and proteoglycans. , 1998, European journal of oral sciences.

[86]  M Tammi,et al.  Hyaluronan synthases. , 1997, The Journal of biological chemistry.

[87]  J. Hopwood,et al.  Lysosomal degradation of heparin and heparan sulphate. , 1992, Advances in experimental medicine and biology.

[88]  M. Glimcher.  The nature of the mineral component of bone and the mechanism of calcification. , 1987, Instructional course lectures.

[89]  R. Franceschi,et al.  1 alpha, 25-dihydroxyvitamin D3 specific regulation of growth, morphology, and fibronectin in a human osteosarcoma cell line. , 1985, Journal of cellular physiology.

[90]  C. A. Thomas,et al.  Molecular cloning. , 1977, Advances in pathobiology.

[91]  R. Lorenc,et al.  The Journal of Pathology , 2022 .