Concomitant activation of ETS-like transcription factor-1 and Death Receptor-5 via extracellular signal-regulated kinase in withaferin A-mediated inhibition of hepatocarcinogenesis in mice

[1]  S. Sukumar,et al.  Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3 , 2017, Oncogene.

[2]  Lingyi Kong,et al.  Eucalrobusone C suppresses cell proliferation and induces ROS-dependent mitochondrial apoptosis via the p38 MAPK pathway in hepatocellular carcinoma cells. , 2017, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[3]  Qiaojia Huang,et al.  Prognostic Value of Ki67 Expression for Patients with Surgically Resected Hepatocellular Carcinoma: Perspectives from a High Incidence Area. , 2017, Clinical laboratory.

[4]  B. Győrffy,et al.  Benzyl Isothiocyanate potentiates p53 signaling and antitumor effects against breast cancer through activation of p53-LKB1 and p73-LKB1 axes , 2017, Scientific Reports.

[5]  Jianing Zhang,et al.  ST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway , 2016, Oncotarget.

[6]  Ahmedin Jemal,et al.  Annual Report to the Nation on the Status of Cancer, 1975‐2012, featuring the increasing incidence of liver cancer , 2016, Cancer.

[7]  Xiaoying Shen,et al.  Expression of MTA2 and Ki-67 in hepatocellular carcinoma and their correlation with prognosis. , 2015, International journal of clinical and experimental pathology.

[8]  Shivendra V. Singh,et al.  Mechanistic elucidation of the antitumor properties of withaferin a in breast cancer. , 2014, Cancer research.

[9]  Sahil Mittal,et al.  Epidemiology of hepatocellular carcinoma: consider the population. , 2013, Journal of clinical gastroenterology.

[10]  E. D. de Vries,et al.  Translating TRAIL-receptor targeting agents to the clinic. , 2013, Cancer letters.

[11]  D. Sharma,et al.  Integral role of PTP1B in adiponectin-mediated inhibition of oncogenic actions of leptin in breast carcinogenesis. , 2013, Neoplasia.

[12]  G. Haegeman,et al.  Molecular insight in the multifunctional activities of Withaferin A. , 2012, Biochemical pharmacology.

[13]  M. Ayers,et al.  Ki67 expression in the primary tumor predicts for clinical benefit and time to progression on first-line endocrine therapy in estrogen receptor-positive metastatic breast cancer , 2012, Breast Cancer Research and Treatment.

[14]  Mohammad Amjad Kamal,et al.  New anticancer agents: recent developments in tumor therapy. , 2012, Anticancer research.

[15]  Philippe P Roux,et al.  Regulation and function of the RSK family of protein kinases. , 2012, The Biochemical journal.

[16]  B. A. Carter,et al.  Assessment of Ki67 in Breast Cancer: Recommendations from the International Ki67 in Breast Cancer Working Group , 2012 .

[17]  J. Arbiser,et al.  Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis , 2012, Breast Cancer Research.

[18]  Jack Cuzick,et al.  Assessment of Ki67 in breast cancer: recommendations from the International Ki67 in Breast Cancer working group. , 2011, Journal of the National Cancer Institute.

[19]  A. Qazi,et al.  Interaction of natural products with cell survival and signaling pathways in the biochemical elucidation of drug targets in cancer. , 2011, Future oncology.

[20]  Lily Yang,et al.  Survivin upregulation, dependent on leptin-EGFR-Notch1 axis, is essential for leptin-induced migration of breast carcinoma cells. , 2011, Endocrine-related cancer.

[21]  Philippe P Roux,et al.  Paving the way for targeting RSK in cancer , 2011, Expert opinion on therapeutic targets.

[22]  Michael R Hamblin,et al.  CA : A Cancer Journal for Clinicians , 2011 .

[23]  A. Jemal,et al.  Global Cancer Statistics , 2011 .

[24]  A. Yang,et al.  Proapoptotic DR4 and DR5 signaling in cancer cells: toward clinical translation. , 2010, Current opinion in cell biology.

[25]  J. Taunton,et al.  ERK/Ribosomal S6 Kinase (RSK) Signaling Positively Regulates Death Receptor 5 Expression through Co-activation of CHOP and Elk1* , 2010, The Journal of Biological Chemistry.

[26]  F. Anania,et al.  Adiponectin modulates C-jun N-terminal kinase and mammalian target of rapamycin and inhibits hepatocellular carcinoma. , 2010, Gastroenterology.

[27]  F. Anania,et al.  Adiponectin antagonizes the oncogenic actions of leptin in hepatocellular carcinogenesis , 2010, Hepatology.

[28]  J. Chambard,et al.  ERK and cell death: Mechanisms of ERK‐induced cell death – apoptosis, autophagy and senescence , 2010, The FEBS journal.

[29]  Jonathan G. Rud,et al.  Phosphorylation of Nur77 by the MEK-ERK-RSK Cascade Induces Mitochondrial Translocation and Apoptosis in T Cells1 , 2009, The Journal of Immunology.

[30]  Javier Palazón,et al.  Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine , 2009, Molecules.

[31]  T. Kwon,et al.  Withaferin A inhibits tumor necrosis factor-alpha-induced expression of cell adhesion molecules by inactivation of Akt and NF-kappaB in human pulmonary epithelial cells. , 2009, International immunopharmacology.

[32]  Yoon-Koo Kang,et al.  Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. , 2009, The Lancet. Oncology.

[33]  S. Paggi,et al.  Sorafenib in Advanced Hepatocellular Carcinoma , 2008 .

[34]  F. Anania,et al.  Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor. , 2008, Cancer research.

[35]  Shivendra V. Singh,et al.  Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo. , 2008, Cancer research.

[36]  R. Tuli,et al.  Analysis of withanolides in root and leaf of Withania somnifera by HPLC with photodiode array and evaporative light scattering detection. , 2008, Phytochemical analysis : PCA.

[37]  A. Pandey,et al.  Withanolides from Withania somnifera roots. , 2008, Phytochemistry.

[38]  A. Hackshaw,et al.  A phase III randomised, double blind, placebo controlled trial of gemcitabine/carboplatin with or without thalidomide in advanced non-small cell lung cancer (NSCLC) , 2007 .

[39]  Didier Merlin,et al.  Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells. , 2007, Cancer research.

[40]  S Beck,et al.  RPS6KA2, a putative tumour suppressor gene at 6q27 in sporadic epithelial ovarian cancer , 2007, Oncogene.

[41]  D. Chendil,et al.  Par-4-dependent apoptosis by the dietary compound withaferin A in prostate cancer cells. , 2007, Cancer research.

[42]  R. Schnellmann,et al.  A Death-Promoting Role for Extracellular Signal-Regulated Kinase , 2006, Journal of Pharmacology and Experimental Therapeutics.

[43]  H. El‐Serag,et al.  Hepatocellular carcinoma: recent trends in the United States. , 2004, Gastroenterology.

[44]  F. Anania,et al.  Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[45]  H. Kaneto,et al.  Cisplatin-induced cell death is EGFR/src/ERK signaling dependent in mouse proximal tubule cells. , 2004, American journal of physiology. Renal physiology.

[46]  T. Barrette,et al.  ONCOMINE: a cancer microarray database and integrated data-mining platform. , 2004, Neoplasia.

[47]  S. Dagenais,et al.  Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. , 2000, Alternative medicine review : a journal of clinical therapeutic.

[48]  A. Jemal,et al.  Global cancer statistics , 2011, CA: a cancer journal for clinicians.

[49]  N. Shao,et al.  Induction of apoptosis by Elk-1 and ΔElk-1 proteins , 1998, Oncogene.

[50]  N. Shao,et al.  Induction of apoptosis by Elk-1 and deltaElk-1 proteins. , 1998, Oncogene.

[51]  C. Slaughter,et al.  ERK phosphorylation potentiates Elk‐1‐mediated ternary complex formation and transactivation. , 1995, The EMBO journal.

[52]  G. Dusheiko,et al.  Management of hepatocellular carcinoma. , 1992, Journal of hepatology.

[53]  Robert C. Wolpert,et al.  A Review of the , 1985 .

[54]  T. Yamane,et al.  Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. , 1982, Cancer research.

[55]  C C Howe,et al.  Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. , 1980, Science.

[56]  J. Satyanarayana.  Recent trends in the United States market for Indian burlap , 1955 .