Identification of miR-200a as a novel suppressor of connexin 43 in breast cancer cells

We demonstrated that miRNA (miR)-200a inhibited connexin 43 (Cx43) expression by directly targeting at the 3’-UTR of Cx43 gene in human breast cancer cells. The miR-200a/Cx43 axis might be a useful diagnostic and therapeutic target of metastatic breast cancer.

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