Discriminative Consistent Domain Generation for Semi-supervised Learning

Deep learning based task systems normally rely on a large amount of manually labeled training data, which is expensive to obtain and subject to operator variations. Moreover, it does not always hold that the manually labeled data and the unlabeled data are sitting in the same distribution. In this paper, we alleviate these problems by proposing a discriminative consistent domain generation (DCDG) approach to achieve a semi-supervised learning. The discriminative consistent domain is achieved by a double-sided domain adaptation. The double-sided domain adaptation aims to make a fusion of the feature spaces of labeled data and unlabeled data. In this way, we can fit the differences of various distributions between labeled data and unlabeled data. In order to keep the discriminativeness of generated consistent domain for the task learning, we apply an indirect learning for the double-sided domain adaptation. Based on the generated discriminative consistent domain, we can use the unlabeled data to learn the task model along with the labeled data via a consistent image generation. We demonstrate the performance of our proposed DCDG on the late gadolinium enhancement cardiac MRI (LGE-CMRI) images acquired from patients with atrial fibrillation in two clinical centers for the segmentation of the left atrium anatomy (LA) and proximal pulmonary veins (PVs). The experiments show that our semi-supervised approach achieves compelling segmentation results, which can prove the robustness of DCDG for the semi-supervised learning using the unlabeled data along with labeled data acquired from a single center or multicenter studies.

[1]  Guang Yang,et al.  Multiview Two-Task Recursive Attention Model for Left Atrium and Atrial Scars Segmentation , 2018, MICCAI.

[2]  King-Sun Fu,et al.  IEEE Transactions on Pattern Analysis and Machine Intelligence Publication Information , 2004, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[3]  Toan Duc Bui,et al.  3D Densely Convolutional Networks for Volumetric Segmentation , 2017, ArXiv.

[4]  Roberto Cipolla,et al.  SegNet: A Deep Convolutional Encoder-Decoder Architecture for Image Segmentation , 2015, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[5]  Guang Yang,et al.  Fully automatic segmentation and objective assessment of atrial scars for long‐standing persistent atrial fibrillation patients using late gadolinium‐enhanced MRI , 2017, Medical physics.

[6]  Qi Tian,et al.  Domain-Invariant Adversarial Learning for Unsupervised Domain Adaption , 2018, ArXiv.

[7]  Nan Feng Zhang,et al.  Deep Learning for Diagnosis of Chronic Myocardial Infarction on Nonenhanced Cardiac Cine MRI. , 2019, Radiology.

[8]  Ming-Hsuan Yang,et al.  Learning to Adapt Structured Output Space for Semantic Segmentation , 2018, 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition.

[9]  Frédéric Jurie,et al.  An Adversarial Regularisation for Semi-Supervised Training of Structured Output Neural Networks , 2017, NIPS 2017.

[10]  Thomas Brox,et al.  U-Net: Convolutional Networks for Biomedical Image Segmentation , 2015, MICCAI.

[11]  Rama Chellappa,et al.  Visual Domain Adaptation: A survey of recent advances , 2015, IEEE Signal Processing Magazine.

[12]  Guang Yang,et al.  Multiview Sequential Learning and Dilated Residual Learning for a Fully Automatic Delineation of the Left Atrium and Pulmonary Veins from Late Gadolinium-Enhanced Cardiac MRI Images , 2018, 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).