Rab GTPase Function in Endosome and Lysosome Biogenesis.
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[1] F. Reggiori,et al. Molecular mechanism to target the endosomal Mon1-Ccz1 GEF complex to the pre-autophagosomal structure , 2018, eLife.
[2] Keiji Tanaka,et al. Endosomal Rab cycles regulate Parkin-mediated mitophagy , 2018, eLife.
[3] B. Glick,et al. Budding Yeast Has a Minimal Endomembrane System. , 2018, Developmental cell.
[4] C. Ungermann,et al. A guanine nucleotide exchange factor (GEF) limits Rab GTPase–driven membrane fusion , 2017, The Journal of Biological Chemistry.
[5] S. Eimer,et al. Control of RAB7 activity and localization through the retromer‐TBC1D5 complex enables RAB7‐dependent mitophagy , 2017, The EMBO journal.
[6] A. Mayer,et al. A tethering complex drives the terminal stage of SNARE-dependent membrane fusion , 2017, Nature.
[7] R. Zoncu,et al. Emerging Roles for the Lysosome in Lipid Metabolism. , 2017, Trends in cell biology.
[8] Edward L. Huttlin,et al. Systematic Analysis of Human Cells Lacking ATG8 Proteins Uncovers Roles for GABARAPs and the CCZ1/MON1 Regulator C18orf8/RMC1 in Macroautophagic and Selective Autophagic Flux , 2017, Molecular and Cellular Biology.
[9] Srigokul Upadhyayula,et al. Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding , 2017, eLife.
[10] Chonglin Yang,et al. WDR91 is a Rab7 effector required for neuronal development , 2017, The Journal of cell biology.
[11] H. Kaur,et al. Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication , 2017, PLoS pathogens.
[12] G. Juhász,et al. Rab2 promotes autophagic and endocytic lysosomal degradation , 2017, The Journal of cell biology.
[13] R. Goody,et al. Mechanisms of action of Rab proteins, key regulators of intracellular vesicular transport , 2017, Biological chemistry.
[14] J. Rizo,et al. A cascade of multiple proteins and lipids catalyzes membrane fusion , 2017, Molecular biology of the cell.
[15] S. Raunser,et al. Multivalent Rab interactions determine tether-mediated membrane fusion , 2017, Molecular biology of the cell.
[16] S. Raunser,et al. Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1–Ccz1 , 2017, Nature Communications.
[17] A. Kiger,et al. Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy , 2016, eLife.
[18] G. Juhász,et al. The Ccz1-Mon1-Rab7 module and Rab5 control distinct steps of autophagy , 2016, Molecular biology of the cell.
[19] Gangming Zhang,et al. The Vici Syndrome Protein EPG5 Is a Rab7 Effector that Determines the Fusion Specificity of Autophagosomes with Late Endosomes/Lysosomes. , 2016, Molecular cell.
[20] J. Bonifacino,et al. Rab5 and its effector FHF contribute to neuronal polarity through dynein-dependent retrieval of somatodendritic proteins from the axon , 2016, Proceedings of the National Academy of Sciences.
[21] W. Wickner,et al. Improved reconstitution of yeast vacuole fusion with physiological SNARE concentrations reveals an asymmetric Rab(GTP) requirement , 2016, Molecular biology of the cell.
[22] Andrei N. Lupas,et al. An endosomal tether undergoes an entropic collapse to bring vesicles together , 2016, Nature.
[23] F. Hughson,et al. Chaperoning SNARE assembly and disassembly , 2016, Nature Reviews Molecular Cell Biology.
[24] G. Juhász,et al. MiniCORVET is a Vps8-containing early endosomal tether in Drosophila , 2016, eLife.
[25] A. Spang. Membrane Tethering Complexes in the Endosomal System , 2016, Front. Cell Dev. Biol..
[26] Natalia Gomez-Navarro,et al. COP-coated vesicles , 2016, Current Biology.
[27] H. Mabuchi,et al. Protein flexibility is required for vesicle tethering at the Golgi , 2015, eLife.
[28] M. Spiess,et al. Rabaptin5 is recruited to endosomes by Rab4 and Rabex5 to regulate endosome maturation , 2015, Journal of Cell Science.
[29] Rik van der Kant,et al. Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity* , 2015, The Journal of Biological Chemistry.
[30] Christer S. Ejsing,et al. The GARP complex is required for cellular sphingolipid homeostasis , 2015, eLife.
[31] P. Jeffrey,et al. A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly , 2015, Science.
[32] C. Ungermann,et al. Identification of a Rab GTPase-activating protein cascade that controls recycling of the Rab5 GTPase Vps21 from the vacuole , 2015, Molecular biology of the cell.
[33] H. Arlt,et al. The I-BAR protein Ivy1 is an effector of the Rab7 GTPase Ypt7 involved in vacuole membrane homeostasis , 2015, Journal of Cell Science.
[34] V. Haucke,et al. A grab to move on: ER–endosome contacts in membrane protrusion formation and neurite outgrowth , 2015, The EMBO journal.
[35] J. Bonifacino,et al. BORC, a multisubunit complex that regulates lysosome positioning. , 2015, Developmental cell.
[36] A. Merz,et al. Ubiquitin binding by the CUE domain promotes endosomal localization of the Rab5 GEF Vps9 , 2015, Molecular biology of the cell.
[37] J. Goldstein,et al. A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins , 2015, Cell.
[38] Michael Davey,et al. Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes , 2015, Molecular biology of the cell.
[39] I. Dikic,et al. PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins. , 2015, Molecular cell.
[40] Y. Kalaidzidis,et al. Mammalian CORVET Is Required for Fusion and Conversion of Distinct Early Endosome Subpopulations , 2014, Traffic.
[41] S. Munro,et al. Toward a Comprehensive Map of the Effectors of Rab GTPases , 2014, Developmental cell.
[42] M. Zerial,et al. Rab proteins and the compartmentalization of the endosomal system. , 2014, Cold Spring Harbor perspectives in biology.
[43] P. Moore,et al. The Vps39-like TRAP1 is an effector of Rab5 and likely the missing Vps3 subunit of human CORVET , 2014, Cellular logistics.
[44] G. Raposo,et al. The complex ultrastructure of the endolysosomal system. , 2014, Cold Spring Harbor perspectives in biology.
[45] C. Ungermann,et al. Principles of membrane tethering and fusion in endosome and lysosome biogenesis. , 2014, Current opinion in cell biology.
[46] M. van der Laan,et al. Cellular metabolism regulates contact sites between vacuoles and mitochondria. , 2014, Developmental cell.
[47] P. Greimel,et al. Lipid compartmentalization in the endosome system. , 2014, Seminars in cell & developmental biology.
[48] G. Jürgens,et al. Protein Delivery to Vacuole Requires SAND Protein-Dependent Rab GTPase Conversion for MVB-Vacuole Fusion , 2014, Current Biology.
[49] C. Ungermann,et al. Dynamic association of the PI3P-interacting Mon1-Ccz1 GEF with vacuoles is controlled through its phosphorylation by the type 1 casein kinase Yck3 , 2014, Molecular biology of the cell.
[50] A. Nakano,et al. Activation of the Rab7 GTPase by the MON1-CCZ1 Complex Is Essential for PVC-to-Vacuole Trafficking and Plant Growth in Arabidopsis[C][W] , 2014, Plant Cell.
[51] T. Natsume,et al. The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17 , 2014, Molecular biology of the cell.
[52] Doris Popovic,et al. TBC1D5 and the AP2 complex regulate ATG9 trafficking and initiation of autophagy , 2014, EMBO reports.
[53] Olivia K. Foster,et al. Caenorhabditis elegans HOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1 , 2014, Molecular biology of the cell.
[54] Matthew West,et al. Fission of SNX-BAR–coated endosomal retrograde transport carriers is promoted by the dynamin-related protein Vps1 , 2014, The Journal of cell biology.
[55] J. Piehler,et al. The Mon1–Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold–Rab interface and association with PI3P-positive membranes , 2014, Journal of Cell Science.
[56] C. Burd,et al. Retromer: a master conductor of endosome sorting. , 2014, Cold Spring Harbor perspectives in biology.
[57] C. Burd,et al. Phosphatidylserine flipping enhances membrane curvature and negative charge required for vesicular transport , 2013, The Journal of cell biology.
[58] D. Owen,et al. Structural basis of Vps33A recruitment to the human HOPS complex by Vps16 , 2013, Proceedings of the National Academy of Sciences.
[59] F. Barr. Rab GTPases and membrane identity: Causal or inconsequential? , 2013, The Journal of cell biology.
[60] P. Jeffrey,et al. Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16* , 2013, PloS one.
[61] T. Taguchi. Emerging roles of recycling endosomes. , 2013, Journal of biochemistry.
[62] A. Merz,et al. Vps9 Family Protein Muk1 Is the Second Rab5 Guanosine Nucleotide Exchange Factor in Budding Yeast* , 2013, The Journal of Biological Chemistry.
[63] M. Fortini,et al. Dmon1 controls recruitment of Rab7 to maturing endosomes in Drosophila , 2013, Journal of Cell Science.
[64] H. Balderhaar,et al. CORVET and HOPS tethering complexes – coordinators of endosome and lysosome fusion , 2013, Journal of Cell Science.
[65] H. Balderhaar,et al. The CORVET complex promotes tethering and fusion of Rab5/Vps21-positive membranes , 2013, Proceedings of the National Academy of Sciences.
[66] H. Arlt,et al. Functional Separation of Endosomal Fusion Factors and the Class C Core Vacuole/Endosome Tethering (CORVET) Complex in Endosome Biogenesis* , 2012, The Journal of Biological Chemistry.
[67] A. Merz,et al. Sec1/Munc18 protein Vps33 binds to SNARE domains and the quaternary SNARE complex , 2012, Molecular biology of the cell.
[68] F. Barr,et al. BLOC-3 Mutated in Hermansky-Pudlak Syndrome Is a Rab32/38 Guanine Nucleotide Exchange Factor , 2012, Current Biology.
[69] M. Seaman. The retromer complex – endosomal protein recycling and beyond , 2012, Journal of Cell Science.
[70] R. Jahn,et al. Molecular machines governing exocytosis of synaptic vesicles , 2012, Nature.
[71] C. Burd,et al. Rab GTPase regulation of retromer-mediated cargo export during endosome maturation , 2012, Molecular biology of the cell.
[72] F. Barr,et al. The Msb3/Gyp3 GAP controls the activity of the Rab GTPases Vps21 and Ypt7 at endosomes and vacuoles , 2012, Molecular biology of the cell.
[73] Sarah Seifert,et al. Rab5 is necessary for the biogenesis of the endolysosomal system in vivo , 2012, Nature.
[74] D. Rigden,et al. Rab14 and Its Exchange Factor FAM116 Link Endocytic Recycling and Adherens Junction Stability in Migrating Cells , 2012, Developmental cell.
[75] S. Raunser,et al. Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex , 2012, Proceedings of the National Academy of Sciences.
[76] P. Verkade,et al. SNX–BAR‐Mediated Endosome Tubulation is Co‐ordinated with Endosome Maturation , 2012, Traffic.
[77] J. Bonifacino,et al. Assembly and Architecture of Biogenesis of Lysosome-related Organelles Complex-1 (BLOC-1)* , 2011, The Journal of Biological Chemistry.
[78] Ari Helenius,et al. Endosome maturation , 2011, The EMBO journal.
[79] Scott D Emr,et al. The ESCRT pathway. , 2011, Developmental cell.
[80] C. Ungermann,et al. HOPS drives vacuole fusion by binding the vacuolar SNARE complex and the Vam7 PX domain via two distinct sites , 2011, Molecular biology of the cell.
[81] C. Brett,et al. Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic , 2011, Molecular biology of the cell.
[82] W. Prinz,et al. A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking , 2011, The Journal of cell biology.
[83] H. Arlt,et al. The Rab GTPase Ypt7 is linked to retromer-mediated receptor recycling and fusion at the yeast late endosome , 2010, Journal of Cell Science.
[84] R. Kucharczyk,et al. Mutants of the Saccharomyces cerevisiae VPS genes CCZ1 and YPT7 are blocked in different stages of sporulation. , 2010, European journal of cell biology.
[85] Qiming Sun,et al. Rubicon controls endosome maturation as a Rab7 effector , 2010, Proceedings of the National Academy of Sciences.
[86] F. Hughson,et al. Tethering factors as organizers of intracellular vesicular traffic. , 2010, Annual review of cell and developmental biology.
[87] C. Ostrowicz,et al. The Mon1-Ccz1 Complex Is the GEF of the Late Endosomal Rab7 Homolog Ypt7 , 2010, Current Biology.
[88] Marino Zerial,et al. Identification of the Switch in Early-to-Late Endosome Transition , 2010, Cell.
[89] Eigen R. Peralta,et al. Differential Effects of TBC1D15 and Mammalian Vps39 on Rab7 Activation State, Lysosomal Morphology, and Growth Factor Dependence* , 2010, The Journal of Biological Chemistry.
[90] K. Ravichandran,et al. Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells , 2010, Nature.
[91] G. Bjørkøy,et al. FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end–directed vesicle transport , 2010, The Journal of cell biology.
[92] N. Bright,et al. Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5 , 2009, Journal of Cell Science.
[93] Y. Kalaidzidis,et al. Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes , 2009, Nature.
[94] F. Reggiori,et al. Ultrastructural Analysis of Nanogold-labeled Endocytic Compartments of Yeast Saccharomyces cerevisiae Using a Cryosectioning Procedure , 2009, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[95] T. Südhof,et al. Membrane Fusion: Grappling with SNARE and SM Proteins , 2009, Science.
[96] J. Bonifacino,et al. Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7 , 2008, The Journal of cell biology.
[97] J. Mulholland,et al. Direct interaction between a myosin V motor and the Rab GTPases Ypt31/32 is required for polarized secretion. , 2008, Molecular biology of the cell.
[98] C. Ostrowicz,et al. Yeast vacuole fusion: A model system for eukaryotic endomembrane dynamics , 2008, Autophagy.
[99] W. Wickner,et al. Excess vacuolar SNAREs drive lysis and Rab bypass fusion , 2007, Proceedings of the National Academy of Sciences.
[100] C. Ostrowicz,et al. The CORVET tethering complex interacts with the yeast Rab5 homolog Vps21 and is involved in endo-lysosomal biogenesis. , 2007, Developmental cell.
[101] C. Burd,et al. Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling , 2007, The Journal of cell biology.
[102] J. Falcón-Pérez,et al. BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes. , 2006, Molecular biology of the cell.
[103] B. Wainer,et al. BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes. , 2006, Molecular biology of the cell.
[104] Reinhard Jahn,et al. SNAREs — engines for membrane fusion , 2006, Nature Reviews Molecular Cell Biology.
[105] J. Bonifacino,et al. The Rab5 Guanine Nucleotide Exchange Factor Rabex-5 Binds Ubiquitin (Ub) and Functions as a Ub Ligase through an Atypical Ub-interacting Motif and a Zinc Finger Domain* , 2006, Journal of Biological Chemistry.
[106] A. Shevchenko,et al. Huntingtin–HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease , 2006, The Journal of cell biology.
[107] T. Cover,et al. The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments. , 2005, Molecular biology of the cell.
[108] Y. Kalaidzidis,et al. Rab Conversion as a Mechanism of Progression from Early to Late Endosomes , 2005, Cell.
[109] P. De Camilli,et al. An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway , 2005, The Journal of cell biology.
[110] F. Barr,et al. A GTPase-activating protein controls Rab5 function in endocytic trafficking , 2005, Nature Cell Biology.
[111] R. Goody,et al. The structural and mechanistic basis for recycling of Rab proteins between membrane compartments , 2005, Cellular and Molecular Life Sciences CMLS.
[112] M. Zerial,et al. The Rab5 Effector Rabankyrin-5 Regulates and Coordinates Different Endocytic Mechanisms , 2004, PLoS biology.
[113] Bianca Habermann,et al. APPL Proteins Link Rab5 to Nuclear Signal Transduction via an Endosomal Compartment , 2004, Cell.
[114] Stefan Matile,et al. Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization , 2004, Science.
[115] A. Wandinger-Ness,et al. Human VPS34 and p150 are Rab7 Interacting Partners , 2003, Traffic.
[116] S. Munro,et al. Long coiled-coil proteins and membrane traffic. , 2003, Biochimica et biophysica acta.
[117] Christopher G. Burd,et al. The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization , 2003, The Journal of cell biology.
[118] J. Hurley,et al. Mechanism of Ubiquitin Recognition by the CUE Domain of Vps9p , 2003, Cell.
[119] Zhijian J. Chen,et al. Vps9p CUE Domain Ubiquitin Binding Is Required for Efficient Endocytic Protein Traffic* , 2003, Journal of Biological Chemistry.
[120] F. Supek,et al. Ubiquitin Signals Protein Trafficking via Interaction with a Novel Ubiquitin Binding Domain in the Membrane Fusion Regulator, Vps9p , 2003, Current Biology.
[121] D. Klionsky,et al. The Ccz1-Mon1 Protein Complex Is Required for the Late Step of Multiple Vacuole Delivery Pathways* , 2002, The Journal of Biological Chemistry.
[122] V. Puri,et al. Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells. , 2002, The Journal of clinical investigation.
[123] Harald Stenmark,et al. Role of Rab5 in the Recruitment of hVps34/p150 to the Early Endosome , 2002, Traffic.
[124] Lawrence M. Lifshitz,et al. Sequential Roles for Phosphatidylinositol 3-Phosphate and Rab5 in Tethering and Fusion of Early Endosomes via Their Interaction with EEA1* 210 , 2002, The Journal of Biological Chemistry.
[125] B. Sönnichsen,et al. Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes , 2002, Nature Cell Biology.
[126] I. Vetter,et al. The Guanine Nucleotide-Binding Switch in Three Dimensions , 2001, Science.
[127] P. Slonimski,et al. The Ccz1 protein interacts with Ypt7 GTPase during fusion of multiple transport intermediates with the vacuole in S. cerevisiae. , 2001, Journal of cell science.
[128] W. Hong,et al. SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P , 2001, Nature Cell Biology.
[129] S. Emr,et al. The Class C Vps Complex Functions at Multiple Stages of the Vacuolar Transport Pathway , 2001, Traffic.
[130] P. Alifano,et al. Rab‐interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes , 2001, The EMBO journal.
[131] Scott D. Emr,et al. New Component of the Vacuolar Class C-Vps Complex Couples Nucleotide Exchange on the Ypt7 Gtpase to Snare-Dependent Docking and Fusion , 2000, The Journal of cell biology.
[132] M. Zerial,et al. Rabenosyn-5, a Novel Rab5 Effector, Is Complexed with Hvps45 and Recruited to Endosomes through a Fyve Finger Domain , 2000, The Journal of cell biology.
[133] W. Wickner,et al. A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[134] V. Rybin,et al. Oligomeric Complexes Link Rab5 Effectors with NSF and Drive Membrane Fusion via Interactions between EEA1 and Syntaxin 13 , 1999, Cell.
[135] G. Tall,et al. The phosphatidylinositol 3-phosphate binding protein Vac1p interacts with a Rab GTPase and a Sec1p homologue to facilitate vesicle-mediated vacuolar protein sorting. , 1999, Molecular biology of the cell.
[136] H. McBride,et al. The Rab5 effector EEA1 is a core component of endosome docking , 1999, Nature.
[137] C. Burd,et al. Vac1p coordinates Rab and phosphatidylinositol 3-kinase signaling in Vps45p-dependent vesicle docking/fusion at the endosome , 1999, Current Biology.
[138] D. Gallwitz,et al. Primary structure and biochemical characterization of yeast GTPase-activating proteins with substrate preference for the transport GTPase Ypt7p. , 1999, European journal of biochemistry.
[139] Marino Zerial,et al. EEA1 links PI(3)K function to Rab5 regulation of endosome fusion , 1998, Nature.
[140] Marino Zerial,et al. A Novel Rab5 GDP/GTP Exchange Factor Complexed to Rabaptin-5 Links Nucleotide Exchange to Effector Recruitment and Function , 1997, Cell.
[141] Rein Aasland,et al. Endosomal Localization of the Autoantigen EEA1 Is Mediated by a Zinc-binding FYVE Finger* , 1996, The Journal of Biological Chemistry.
[142] M. Zerial,et al. Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion , 1995, Cell.
[143] Y. Goda,et al. Rab9 functions in transport between late endosomes and the trans Golgi network. , 1993, The EMBO journal.
[144] J. Brown,et al. Endocytosis from coated pits of Shiga toxin: a glycolipid-binding protein from Shigella dysenteriae 1 , 1989, The Journal of cell biology.
[145] Joseph L. Goldstein,et al. Recycling receptors: The round-trip itinerary of migrant membrane proteins , 1983, Cell.
[146] L. Orci,et al. Co-localization of 125I-epidermal growth factor and ferritin-low density lipoprotein in coated pits: a quantitative electron microscopic study in normal and mutant human fibroblasts , 1982, The Journal of cell biology.
[147] C. Ungermann,et al. The BLOC-1 complex promotes endosomal maturation by recruiting the Rab 5 GTPase-activating protein Msb 3 , 2013 .
[148] B. Horazdovsky,et al. Vps9 domain-containing proteins: activators of Rab5 GTPases from yeast to neurons. , 2006, Trends in cell biology.
[149] J. Bonifacino,et al. Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5 , 2006, Nature Structural &Molecular Biology.