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Accumulation of mtDNA with a mutation at position 3271 in tRNA(Leu)(UUR) gene introduced from a MELAS patient to HeLa cells lacking mtDNA results in progressive inhibition of mitochondrial respiratory function.
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R. Sakuta
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J. Hayashi
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S. Ohta
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Y. Goto
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I. Nonaka
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S. Miyabayashi
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D. Takai
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