Neurotoxicity of a prion protein fragment

[1]  G. Forloni,et al.  Expression of amyloid precursor protein mRNAs in endothelial, neuronal and glial cells: modulation by interleukin-1. , 1992, Brain research. Molecular brain research.

[2]  S. Prusiner,et al.  Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[3]  D. Borchelt,et al.  Toxicity of synthetic aβ peptides and modeling of alzheimer's disease , 1992, Neurobiology of Aging.

[4]  D. Stephenson,et al.  Implants containing β-amyloid protein are not neurotoxic to young and old rat brain , 1992, Neurobiology of Aging.

[5]  C. Geula,et al.  The acute neurotoxicity and effects upon cholinergic axons of intracerebrally injected β-amyloid in the rat brain , 1992, Neurobiology of Aging.

[6]  Carl W. Cotman,et al.  In vitro aging of ß-amyloid protein causes peptide aggregation and neurotoxicity , 1991, Brain Research.

[7]  P. Fraser,et al.  pH-dependent structural transitions of Alzheimer amyloid peptides. , 1991, Biophysical journal.

[8]  M. Beal,et al.  An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[9]  S. Prusiner,et al.  Molecular biology of prion diseases , 1991, Science.

[10]  S. Prusiner,et al.  Amyloid protein of Gerstmann‐Sträussler‐Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N‐terminal glycine at codon 58. , 1991, EMBO Journal.

[11]  D. Kirschner,et al.  Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. , 1990, Science.

[12]  Seamus J. Martin,et al.  Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis. , 1990, Journal of immunology.

[13]  W. Tourtellotte,et al.  Changes in brain gene expression shared by scrapie and Alzheimer disease. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[14]  P. McBride,et al.  Precise targeting of the pathology of the sialoglycoprotein, PrP, and vacuolar degeneration in mouse scrapie , 1989, Neuroscience Letters.

[15]  P. Gilna,et al.  Identification of an androgen-repressed mRNA in rat ventral prostate as coding for sulphated glycoprotein 2 by cDNA cloning and sequence analysis. , 1989, The Biochemical journal.

[16]  M. Tenniswood,et al.  Treatment with antiandrogens induces an androgen‐repressed gene in the rat ventral prostate , 1988, The Prostate.

[17]  S. Prusiner,et al.  Changes in the localization of brain prion proteins during scrapie infection , 1987, Neurology.

[18]  S. Prusiner,et al.  Separation and properties of cellular and scrapie prion proteins. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[19]  S. Prusiner,et al.  Scrapie prion proteins are synthesized in neurons. , 1986, The American journal of pathology.

[20]  M. Tenniswood,et al.  Androgen‐repressed messages in the rat ventral prostate , 1986, The Prostate.

[21]  B. Chesebro,et al.  Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain , 1985, Nature.

[22]  M. Braunfeld,et al.  Identification of prion amyloid filaments in scrapie-infected brain , 1985, Cell.

[23]  Ruedi Aebersold,et al.  A cellular gene encodes scrapie PrP 27-30 protein , 1985, Cell.

[24]  B. Aggarwal,et al.  Human lymphotoxin. Production by a lymphoblastoid cell line, purification, and initial characterization. , 1984, The Journal of biological chemistry.

[25]  S. Prusiner,et al.  Scrapie prions aggregate to form amyloid-like birefringent rods , 1983, Cell.

[26]  S. Prusiner,et al.  A protease-resistant protein is a structural component of the Scrapie prion , 1983, Cell.

[27]  S. Prusiner,et al.  Identification of a protein that purifies with the scrapie prion. , 1982, Science.

[28]  S. Prusiner,et al.  Further purification and characterization of scrapie prions. , 1982, Biochemistry.

[29]  A. Wyllie.  Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation , 1980, Nature.

[30]  A. Wyllie,et al.  Cell death: the significance of apoptosis. , 1980, International review of cytology.