Decreased signaling competence as a result of receptor overexpression: overexpression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytes.
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K. M. Abraham | R. Perlmutter | A. Singer | D. Wiest | T. Nakayama | T. Munitz | Toshinori Nakayama | Alfred Singer | Kristin M. Abraham | David L. Wiest