Aetiological examination of an outbreak of haemorrhagic syndrome in a broiler flock in Japan.

The aetiology of an outbreak of haemorrhagic syndrome (HS) in a commercial broiler flock was examined. At a rearing farm, 596 of 6376 chicks (9.3%) in a flock were culled with depression and increased mortality from 12 to 26 days of age, with a peak at 16 to 19 days of age. Most of the affected chicks examined had haemorrhagic lesions of the muscles, atrophic changes of the lymphoid organs and aplastic bone marrow. Chicken anaemia agent (CAA) was isolated from the livers of all the 21 chicks examined. No fowl adenovirus was isolated. The present field case of HS coincides fairly well with the disease which is produced experimentally by CAA.

[1]  V. V. Bülow,et al.  Erhöhte Pathogenität des Erregers der aviären infektiösen Anämie bei Hühnerküken (CAA) bei simultaner Infektion mit Virus der Marekschen Krankheit (MDV), Bursitisvirus (IBDV) oder Reticuloendotheliosevirus (REV)* , 1986 .

[2]  K. Imai,et al.  Pathogenicity and antigenicity of eleven isolates of chicken anaemia agent (CAA). , 1986, Avian pathology : journal of the W.V.P.A.

[3]  K. Imai,et al.  Survey of antibody against chicken anaemia agent (CAA) by an indirect immunofluorescent antibody technique in breeder flocks in Japan. , 1985, Avian pathology : journal of the W.V.P.A.

[4]  H. Hihara,et al.  Isolation of chicken anemia agent with MDCC-MSB1 cells from chickens in the field. , 1983, National Institute of Animal Health quarterly.

[5]  N. Yuasa.  Propagation and infectivity titration of the Gifu-1 strain of chicken anemia agent in a cell line (MDCC-MSB1) derived from Marek's disease lymphoma. , 1983, National Institute of Animal Health quarterly.

[6]  N. Yuasa,et al.  Experimental egg transmission of chicken anemia agent. , 1983, National Institute of Animal Health quarterly.

[7]  T. Taniguchi,et al.  Chronological observations on hemato-pathological changes in chicks inoculated with chicken anemia agent. , 1983, National Institute of Animal Health quarterly.

[8]  T. Taniguchi,et al.  Hematopathological changes in dead and moribund chicks induced by chicken anemia agent. , 1982, National Institute of Animal Health quarterly.

[9]  T. Taniguchi,et al.  Effect of infectious bursal disease virus infection on incidence of anemia by chicken anemia agent. , 1980 .

[10]  T. Taniguchi,et al.  Isolation and some characteristics of an agent inducing anemia in chicks. , 1979 .

[11]  K. Sh,et al.  Involvement of a type-8 avian adenovirus in the etiology of inclusion body hepatitis. , 1977 .

[12]  B. Adair,et al.  Avian adenoviruses--a review. , 1977, Avian pathology : journal of the W.V.P.A.

[13]  J. Mcferran,et al.  Experimental studies on the aetiology of inclusion body hepatitis. , 1976, Avian pathology : journal of the W.V.P.A.

[14]  R. Eckroade,et al.  The roles of the infectious bursal agent and several avian adenoviruses in the hemorrhagic-aplastic-anemia syndrome and gangrenous dermatitis. , 1975, Avian diseases.

[15]  J. Rosenberger,et al.  Diagnosis of inclusion body hepatitis and hemorrhagic anemia syndrome in Delmarva broiler chickens. , 1975, Avian diseases.

[16]  I. Macpherson,et al.  Inclusion body hepatitis in a broiler integration , 1974, Veterinary Record.

[17]  R. Eckroade,et al.  Characterization of several viruses isolated from chickens with inclusion body hepatitis and aplastic anemia. , 1974, Avian diseases.

[18]  Winterfield Rw,et al.  Isolation and some characteristics of an agent associated with inclusion body hepatitis, hemorrhages, and aplastic anemia in chickens. , 1973 .

[19]  Helmboldt Cf,et al.  Avian hepatic inclusion bodies of unknown significance. , 1963 .

[20]  J. E. Hanley.  Observations on Avian Aplastic Anemia in Florida , 1962 .

[21]  G. Snoeyenbos,et al.  The hemorrhagic syndrome of chickens. , 1954, Journal of the American Veterinary Medical Association.