TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development.
暂无分享,去创建一个
R Wieser | J. Chirgwin | J. Massagué | R. Wieser | T. Guise | G. Mundy | M. Dallas | J Massagué | J. Yin | M Dallas | B. Grubbs | J J Yin | J M Chirgwin | G R Mundy | K. Selander | T A Guise | K Selander | B G Grubbs | J. Yin | John M. Chirgwin | Gregory R. Mundy | Juan Juan Yin | Katri Selander | Mark Dallas | Barry Grubbs | Rotraud Wieser | Joan Massagué | Theresa A. Guise
[1] R. Coffey,et al. Mammary tumor suppression by transforming growth factor beta 1 transgene expression. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[2] M. Klagsbrun,et al. Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-Sepharose. , 1986, The Journal of biological chemistry.
[3] J. Bingham. Letter: Lower oesophageal sphincter. , 1974, Lancet.
[4] G. Strewler,et al. Parathyroid hormonelike protein from human renal carcinoma cells. Structural and functional homology with parathyroid hormone. , 1987, The Journal of clinical investigation.
[5] A. F. Stewart,et al. Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercalcemia of malignancy. , 1987, The Journal of biological chemistry.
[6] Scott E. Kern,et al. DPC4, A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1 , 1996, Science.
[7] M. Pandian,et al. Modified immunoradiometric assay of parathyroid hormone-related protein: clinical application in the differential diagnosis of hypercalcemia. , 1992, Clinical chemistry.
[8] M. Olivé,et al. Breast tumor cell lines from pleural effusions. , 1974, Journal of the National Cancer Institute.
[9] Irene L Andrulis,et al. MADR2 Maps to 18q21 and Encodes a TGFβ–Regulated MAD–Related Protein That Is Functionally Mutated in Colorectal Carcinoma , 1996, Cell.
[10] B F Boyce,et al. Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice. , 1995, Cancer research.
[11] Allan Balmain,et al. TGFβ1 Inhibits the Formation of Benign Skin Tumors, but Enhances Progression to Invasive Spindle Carcinomas in Transgenic Mice , 1996, Cell.
[12] M. Freeman,et al. A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide. , 1991, Science.
[13] Jane M. Moseley,et al. Transforming growth factor beta stimulation of parathyroid hormone-related protein (PTHrP): a paracrine regulator? , 1993, Molecular and Cellular Endocrinology.
[14] G. Mundy,et al. Modulation of type beta transforming growth factor activity in bone cultures by osteotropic hormones. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[15] J. Chirgwin,et al. Chinese hamster ovarian cells transfected with human parathyroid hormone-related protein cDNA cause hypercalcemia in nude mice. , 1992, Laboratory investigation; a journal of technical methods and pathology.
[16] J. Willson,et al. Expression of transforming growth factor β type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells , 1994 .
[17] R. Rubens,et al. The clinical course of bone metastases from breast cancer. , 1987, British Journal of Cancer.
[18] M. Freeman,et al. Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[19] R Wieser,et al. Signaling activity of transforming growth factor beta type II receptors lacking specific domains in the cytoplasmic region , 1993, Molecular and cellular biology.
[20] J. Massagué. TGF-beta signal transduction. , 1998, Annual review of biochemistry.
[21] J. Graff,et al. Smad3 Mutant Mice Develop Metastatic Colorectal Cancer , 1998, Cell.
[22] J. Massagué,et al. Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin , 1994, Molecular and cellular biology.
[23] C. Caulin,et al. Chronic exposure of cultured transformed mouse epidermal cells to transforming growth factor-beta 1 induces an epithelial-mesenchymal transdifferentiation and a spindle tumoral phenotype. , 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[24] L. Wakefield,et al. Expression of a dominant‐negative mutant TGF‐β type II receptor in transgenic mice reveals essential roles for TGF‐β in regulation of growth and differentiation in the exocrine pancreas , 1997 .
[25] J. Massagué,et al. TGF- SIGNAL TRANSDUCTION , 1998 .
[26] J. Hayman,et al. Localization of parathyroid hormone-related protein in breast cancer metastases: increased incidence in bone compared with other sites. , 1991, Cancer research.
[27] R. Derynck,et al. TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors , 1994, The Journal of cell biology.
[28] G. Hortobagyi,et al. Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. Protocol 19 Aredia Breast Cancer Study Group. , 1996, The New England journal of medicine.
[29] A. Boyde,et al. Scanning electron microscopy in bone pathology: review of methods, potential and applications. , 1986, Scanning electron microscopy.
[30] R. Warrell,et al. Immunochemical characterization of circulating parathyroid hormone-related protein in patients with humoral hypercalcemia of cancer. , 1990, The New England journal of medicine.
[31] L. Suva,et al. Parathyroid hormone-related protein purified from a human lung cancer cell line. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[32] J. Uitto,et al. Revertant Mosaicism in Epidermolysis Bullosa Caused by Mitotic Gene Conversion , 1997, Cell.
[33] T. Rosol,et al. Effects of transforming growth factor-beta on parathyroid hormone-related protein production and ribonucleic acid expression by a squamous carcinoma cell line in vitro. , 1994, Endocrinology.
[34] B F Boyce,et al. Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis. , 1996, The Journal of clinical investigation.
[35] D. Wallwiener,et al. Reduction in new metastases in breast cancer with adjuvant clodronate treatment. , 1998, The New England journal of medicine.
[36] S Paget,et al. THE DISTRIBUTION OF SECONDARY GROWTHS IN CANCER OF THE BREAST. , 1889 .
[37] L. Reimer,et al. Scanning Electron Microscopy , 1984 .
[38] T. Martin,et al. Cell-specific and regulator-induced promoter usage and messenger ribonucleic acid splicing for parathyroid hormone-related protein. , 1996, Endocrinology.
[39] N. Rosen,et al. A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines. , 1995, Cancer research.
[40] K. Kinzler,et al. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. , 1995, Science.
[41] Hiroyuki Miyoshi,et al. Intestinal Tumorigenesis in Compound Mutant Mice of both Dpc4(Smad4) and Apc Genes , 1998, Cell.
[42] M. Kretzschmar,et al. Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1 , 1997, Nature.
[43] J. Hayman,et al. Immunohistochemical localization of parathyroid hormone-related protein in human breast cancer. , 1990, Cancer research.
[44] L. Wakefield,et al. Transgenic Mice Overexpressing a Dominant-negative Mutant Type II Transforming Growth Factor β Receptor Show Enhanced Tumorigenesis in the Mammary Gland and Lung in Response to the Carcinogen 7,12-Dimethylbenz-[a]-anthracene , 1997 .
[45] J. Ratcliffe,et al. Parathyroid hormone related protein and hypercalcaemia in breast cancer. , 1991, BMJ.
[46] J. Massagué,et al. GS domain mutations that constitutively activate T beta R‐I, the downstream signaling component in the TGF‐beta receptor complex. , 1995, The EMBO journal.
[47] H. Beug,et al. TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. , 1996, Genes & development.