A transcriptional switch governs fibroblast activation in heart disease

[1]  Andrew J. Hill,et al.  A human cell atlas of fetal chromatin accessibility , 2020, Science.

[2]  Catherine L. Worth,et al.  Cells of the adult human heart , 2020, Nature.

[3]  Weifeng He,et al.  Molecular Mechanism of Mesenchyme Homeobox 1 in Transforming Growth Factor β1–Induced P311 Gene Transcription in Fibrosis , 2020, Frontiers in Molecular Biosciences.

[4]  Saptarsi M. Haldar,et al.  BET Bromodomain Proteins Regulate Transcriptional Reprogramming in Genetic Dilated Cardiomyopathy , 2020, bioRxiv.

[5]  Katherine S. Pollard,et al.  CellWalker integrates single-cell and bulk data to resolve regulatory elements across cell types in complex tissues , 2019, Genome biology.

[6]  Saptarsi M. Haldar,et al.  Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation. , 2019, Circulation research.

[7]  J. Thompson,et al.  RNA sequencing of transplant-stage idiopathic pulmonary fibrosis lung reveals unique pathway regulation , 2019, ERJ Open Research.

[8]  Saptarsi M. Haldar,et al.  Dynamic chromatin targeting of BRD4 stimulates cardiac fibroblast activation , 2019, bioRxiv.

[9]  Lianfeng Zhang,et al.  Meox1 accelerates myocardial hypertrophic decompensation through Gata4 , 2018, Cardiovascular research.

[10]  L. Lau,et al.  Resolution of organ fibrosis , 2018, Journal of Clinical Investigation.

[11]  Saptarsi M. Haldar,et al.  BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure , 2017, Science Translational Medicine.

[12]  B. Aronow,et al.  Genetic lineage tracing defines myofibroblast origin and function in the injured heart , 2016, Nature Communications.

[13]  Leighton J. Core,et al.  Base-pair-resolution genome-wide mapping of active RNA polymerases using precision nuclear run-on (PRO-seq) , 2016, Nature Protocols.

[14]  Don C Rockey,et al.  Fibrosis--a common pathway to organ injury and failure. , 2015, The New England journal of medicine.

[15]  Howard Y. Chang,et al.  ATAC‐seq: A Method for Assaying Chromatin Accessibility Genome‐Wide , 2015, Current protocols in molecular biology.

[16]  J. Qi,et al.  BET acetyl-lysine binding proteins control pathological cardiac hypertrophy. , 2013, Journal of molecular and cellular cardiology.

[17]  Saptarsi M. Haldar,et al.  BET Bromodomains Mediate Transcriptional Pause Release in Heart Failure , 2013, Cell.

[18]  Luke A. Gilbert,et al.  CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes , 2013, Cell.

[19]  David A. Orlando,et al.  Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes , 2013, Cell.

[20]  William B. Smith,et al.  Selective inhibition of BET bromodomains , 2010, Nature.

[21]  J. Ragoussis,et al.  A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers , 2010, PLoS biology.

[22]  M. Nguyen,et al.  Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton. , 2009, Developmental biology.

[23]  D. Rockey,et al.  Fibrosis--A Common Pathway to Organ Injury and Failure. , 2015, The New England journal of medicine.

[24]  M. Biddle,et al.  A report from the American Heart Association Council on Cardiovascular and Stroke Nursing. , 2015, The Journal of cardiovascular nursing.