Zenker Diverticulum Treatment: Endoscopic or Surgical?

Introduction: The Zenker Diverticulum is a rare pathology, the selection of patients for invasive treatments is questionable, as well as the applied therapeutic method. The aim of the study is to evaluate the main methods of classical and endoscopic surgical treatment in this pathology and to correlate pathophysiological aspects with clinical consequences. MATERIAL AND METHOD We included 36 patients with Zenker hypopharyngeal diverticulum treated in 2010/2017 in two university clinics: 7 patients by classical surgical approach at the General and Esophageal Surgery Clinic of St. Mary's Hospital Bucharest and 29 patients with endoscopic approach at Department of Diagnostic and Interventional Digestive Endoscopy of the Regional Institute of Hepatology and Gastroenterology Prof Dr Octavian Fodor, Cluj-Napoca. The age of the patients ranged from 42 to 84 years and in the 7th to 15th decade. Results: Cricopharyngeal myotomy was performed in all patients. Diverticullectomy was performed in 7 patients treated surgically. The average hospitalization duration was 4 days. Intra-procedural complications showed 3 patients treated endoscopically and consisted of laminar haemorrhage. Two patients were treated with endoscopic endoscopic hemostasis and hot pens and one patient had endoscopic hemostasis with clips. The post-procedural complications were: local pain, leukocytosis, melena, fever, cervical hematoma. These post-treatment events were seen in 6 patients. The posttreatment morbidity was 16.66%. Conclusions: In patients included in the batch, the endoscopic treatment efficiency was 80%. Peristent postinterventional symptomatology was mainly represented by dysphagia, post-procedural syndrome was associated with dysphagia persistence. Patients with persistent post-surgical symptoms were required to reintervention.

[1]  C. Mulder,et al.  New and emerging techniques for endoscopic treatment of Zenker's diverticulum: State‐of‐the‐art review , 2018, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

[2]  E. Parlak,et al.  Endoscopic Treatment of the Zenker Diverticulum With Flexible Endoscopic Myotomy: A Single Tertiary Center Experience , 2017, Surgical laparoscopy, endoscopy & percutaneous techniques.

[3]  R. Rosati,et al.  Treatment of Zenker’s Diverticulum With Endoscopic Stapled Esophago-divertisculostomy (ESD): Analysis of Long-term Outcome , 2017, Surgical laparoscopy, endoscopy & percutaneous techniques.

[4]  T. Rösch,et al.  New flexible endoscopic controlled stapler technique for the treatment of Zenker's diverticulum: A case series , 2017, World journal of gastroenterology.

[5]  W. Bernardo,et al.  Endoscopic versus surgical approach in the treatment of Zenker’s diverticulum: systematic review and meta-analysis , 2016, Endoscopy International Open.

[6]  A. Aiolfi,et al.  Current status of minimally invasive endoscopic management for Zenker diverticulum. , 2015, World journal of gastrointestinal endoscopy.

[7]  J. Shapiro,et al.  A Comparative Study of Outcomes for Endoscopic Diverticulotomy versus External Diverticulectomy , 2014, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[8]  T. Baron,et al.  Flexible endoscopic and surgical management of Zenker's diverticulum , 2012, Expert review of gastroenterology & hepatology.

[9]  F. Herbella,et al.  Modern pathophysiology and treatment of esophageal diverticula , 2011, Langenbeck's Archives of Surgery.

[10]  A. Szold,et al.  Endoscopically stapled diverticulostomy for Zenker’s diverticulum: results of a multidisciplinary team approach , 2010, Surgical Endoscopy.

[11]  R. Fenton,et al.  Staple-assisted endoscopic management of Zenker’s diverticula: a role in the geriatric population , 2009, Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India.

[12]  T. Baron,et al.  Zenker's diverticula: pathophysiology, clinical presentation, and flexible endoscopic management. , 2008, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.

[13]  J. Dent,et al.  Influence of surgery on deglutitive upper oesophageal sphincter mechanics in Zenker's diverticulum. , 1996, Gut.

[14]  J. Dent,et al.  Pharyngeal (Zenker's) diverticulum is a disorder of upper esophageal sphincter opening. , 1992, Gastroenterology.

[15]  P. J. Gullane,et al.  Zenker's diverticulum. , 1983, The Journal of otolaryngology.