Identification of Antitumor Active Constituents in Polygonatum sibiricum Flower by UPLC-Q-TOF-MSE and Network Pharmacology
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[1] J. Fernández-Irigoyen,et al. Profound Reprogramming towards Stemness in Pancreatic Cancer Cells as Adaptation to AKT Inhibition , 2020, Cancers.
[2] Wei Zheng,et al. Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma , 2020, Oncology letters.
[3] J. Chiang,et al. Jagged2 progressively increased expression from Stage I to III of Bladder Cancer and Melatonin-mediated downregulation of Notch/Jagged2 suppresses the Bladder Tumorigenesis via inhibiting PI3K/AKT/mTOR/MMPs signaling , 2020, International journal of biological sciences.
[4] N. Lu,et al. Wogonin induces cellular senescence in breast cancer via suppressing TXNRD2 expression , 2020, Archives of Toxicology.
[5] M. Campone,et al. Targeting the PI3K/Akt/mTOR pathway in estrogen-receptor positive HER2 negative advanced breast cancer , 2020, Therapeutic advances in medical oncology.
[6] Shu-wen Yu,et al. Combined chemotherapy with cyclooxygenase-2 (COX-2) inhibitors in treating human cancers: Recent advancement. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[7] D. G. Parambi,et al. Fascinating chemo preventive story of wogonin: A chance to hit on the head in cancer treatment. , 2020, Current pharmaceutical design.
[8] Hao Yang,et al. Targeting PIK3CG in Combination with Paclitaxel as a Potential Therapeutic Regimen in Claudin-Low Breast Cancer , 2020, Cancer management and research.
[9] Xiaoyu Xie,et al. A novel cell membrane-cloaked magnetic nanogripper with enhanced stability for drug discovery. , 2019, Biomaterials science.
[10] Ruiqi Cao,et al. Stability Designs of Cell Membrane Cloaked Magnetic Carbon Nanotubes for Improved Life Span in Drug Leads Screening. , 2019, Analytical chemistry.
[11] Huan Zhao,et al. Chemical constituents from the rhizomes of Polygonatum sibiricum Red. and anti-inflammatory activity in RAW264.7 macrophage cells , 2019, Natural product research.
[12] Yue Wang,et al. Rhamnetin induces apoptosis in human breast cancer cells via the miR-34a/Notch-1 signaling pathway. , 2018, Oncology letters.
[13] Y. I. Morozik,et al. Determination of the Structure of Alkyl Radicals in a Series of Highly Toxic Organophosphorus Compounds Using Mass Spectrometry Databases and Library Search , 2018, Journal of Analytical Chemistry.
[14] Guohua Yu,et al. Network pharmacology-based strategy to investigate pharmacological mechanisms of Zuojinwan for treatment of gastritis , 2018, BMC Complementary and Alternative Medicine.
[15] N. Lu,et al. Selective anti‐tumor activity of wogonin targeting the Warburg effect through stablizing p53 , 2018, Pharmacological research.
[16] A. López-Cortés,et al. Mutational Analysis of Oncogenic AKT1 Gene Associated with Breast Cancer Risk in the High Altitude Ecuadorian Mestizo Population , 2018, BioMed research international.
[17] Hui Cao,et al. A Review: The Bioactivities and Pharmacological Applications of Polygonatum sibiricum polysaccharides , 2018, Molecules.
[18] Shan Lin,et al. The profiling and identification of chemical components, prototypes and metabolites of Run-zao-zhi-yang capsule in rat plasma, urine and bile by an UPLC-Q-TOF/MSE -based high-throughput strategy. , 2018, Biomedical chromatography : BMC.
[19] M. Xiang,et al. Exploring the Mechanism of Dangguiliuhuang Decoction Against Hepatic Fibrosis by Network Pharmacology and Experimental Validation , 2018, Front. Pharmacol..
[20] S. Olgen. Overview on Anticancer Drug Design and Development. , 2017, Current medicinal chemistry.
[21] Lei Zhang,et al. Combination of wogonin and sorafenib effectively kills human hepatocellular carcinoma cells through apoptosis potentiation and autophagy inhibition. , 2017, Oncology letters.
[22] Jinan Wang,et al. Systems pharmacology exploration of botanic drug pairs reveals the mechanism for treating different diseases , 2016, Scientific Reports.
[23] M. Malkowski,et al. Crystal structure of rofecoxib bound to human cyclooxygenase-2. , 2016, Acta crystallographica. Section F, Structural biology communications.
[24] Michael G. Malkowski,et al. Substrate-selective Inhibition of Cyclooxygeanse-2 by Fenamic Acid Derivatives Is Dependent on Peroxide Tone* , 2016, The Journal of Biological Chemistry.
[25] M. Malkowski,et al. Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry. , 2016, Biochemistry.
[26] Yan Shi,et al. MicroRNA MIR 21 ( miR-21 ) and PTGS 2 Expression in Colorectal Cancer and Patient Survival , 2016 .
[27] A. Jassbi,et al. Microbial biotransformation of bioactive flavonoids. , 2015, Biotechnology advances.
[28] Zaiqi Zhang,et al. Synergy effects of herb extracts: pharmacokinetics and pharmacodynamic basis. , 2014, Fitoterapia.
[29] L. Kang,et al. Rapid isolation of new furostanol saponins from fenugreek seeds based on ultra-performance liquid chromatography coupled with a hybrid quadrupole time-of-flight tandem mass spectrometry. , 2012, Journal of separation science.
[30] L. Kang,et al. Characterization of steroidal glycosides from the extract of Paris Polyphylla var. Yunnanensis by UPLC/Q-TOF MSE. , 2012, Journal of pharmaceutical and biomedical analysis.
[31] Emma E Vincent,et al. Akt signalling in health and disease. , 2011, Cellular signalling.
[32] Anne Fernandez,et al. Akt 1 and Akt 2 : Differentiating the aktion , 2011 .
[33] Enrique Casado,et al. PI3K/Akt signalling pathway and cancer. , 2004, Cancer treatment reviews.