Saturation-inversion-recovery: A method for T1 measurement.

Spin-lattice relaxation (T1) has always been measured by inversion-recovery (IR), saturation-recovery (SR), or related methods. These existing methods share a common behavior in that the function describing T1 sensitivity is the exponential, e.g., exp(-τ/T1), where τ is the recovery time. In this paper, we describe a saturation-inversion-recovery (SIR) sequence for T1 measurement with considerably sharper T1-dependence than those of the IR and SR sequences, and demonstrate it experimentally. The SIR method could be useful in improving the contrast between regions of differing T1 in T1-weighted MRI.

[1]  Alex L. MacKay,et al.  Quantitative interpretation of NMR relaxation data , 1989 .

[2]  Yi-Qiao Song,et al.  Resolution and uncertainty of Laplace inversion spectrum. , 2007, Magnetic resonance imaging.

[3]  R. L. Kleinberg,et al.  NMR Properties of Reservoir Fluids , 1996 .

[4]  Michael Prange,et al.  Quantifying uncertainty in NMR T2 spectra using Monte Carlo inversion. , 2009, Journal of magnetic resonance.

[5]  Redouane Hajjar,et al.  Determination of NMR cogwheel phase cycle with XML. , 2009, Solid state nuclear magnetic resonance.

[6]  M. Levitt,et al.  Multiplex phase cycling. , 2003, Journal of magnetic resonance.

[7]  Colan E Hughes,et al.  Cogwheel phase cycling. , 2002, Journal of magnetic resonance.

[8]  Y. Song Categories of coherence pathways for the CPMG sequence. , 2002, Journal of magnetic resonance.

[9]  McClung,et al.  Construction of phase cycles of minimum cycle length: MakeCycle , 2000, Journal of magnetic resonance.

[10]  E. Sigmund,et al.  Rapid T1 measurement via decay-recovery decomposition: applications in fringe field and distributed relaxation experiments. , 2006, Solid state nuclear magnetic resonance.

[11]  Lalitha Venkataramanan,et al.  Determining the resolution of Laplace inversion spectrum. , 2005, The Journal of chemical physics.

[12]  M. Levitt Spin Dynamics: Basics of Nuclear Magnetic Resonance , 2001 .

[13]  Yi-Qiao Song,et al.  A one-shot method for measurement of diffusion. , 2004, Journal of magnetic resonance.

[14]  R. Parker,et al.  Assigning uncertainties in the inversion of NMR relaxation data. , 2005, Journal of magnetic resonance.

[15]  L Venkataramanan,et al.  T(1)--T(2) correlation spectra obtained using a fast two-dimensional Laplace inversion. , 2002, Journal of magnetic resonance.

[16]  Kevin P. Munn,et al.  A NMR technique for the analysis of pore structure: Numerical inversion of relaxation measurements , 1987 .

[17]  Alex D. Bain,et al.  Coherence levels and coherence pathways in NMR. A simple way to design phase cycling procedures , 1984 .

[18]  G. C. Borgia,et al.  Uniform-penalty inversion of multiexponential decay data. II. Data spacing, T(2) data, systemic data errors, and diagnostics. , 2000, Journal of magnetic resonance.