Advances in skin cancer early detection and diagnosis.

OBJECTIVES To provide an overview of 1) traditional methods of skin cancer early detection, 2) current technologies for skin cancer detection, and 3) evolving practice models of early detection. DATA SOURCES Peer-reviewed databased articles and reviews, scholarly texts, and Web-based resources. CONCLUSION Early detection of skin cancer through established methods or newer technologies is critical for reducing both skin cancer mortality and the overall skin cancer burden. IMPLICATIONS FOR NURSING PRACTICE A basic knowledge of recommended skin examination guidelines and risk factors for skin cancer, traditional methods to further examine lesions that are suspicious for skin cancer and evolving detection technologies can guide patient education and skin inspection decisions.

[1]  M A Weinstock,et al.  Thorough skin examination for the early detection of melanoma. , 1999, American journal of preventive medicine.

[2]  M. Nestor.  The use of mid-level providers in dermatology: a liability risk? , 2005, Seminars in cutaneous medicine and surgery.

[3]  Rainer Hofmann-Wellenhof,et al.  Mobile teledermatology: a feasibility study of 58 subjects using mobile phones , 2008, Journal of telemedicine and telecare.

[4]  J. Aitken,et al.  Diagnosis and management costs of suspicious skin lesions from a population-based melanoma screening programme , 2007, Journal of medical screening.

[5]  Lin Fritschi,et al.  The incidence of second primary invasive melanoma in Queensland, 1982–2003 , 2007, Cancer Causes & Control.

[6]  R. Hofmann-Wellenhof,et al.  Cellular phones in clinical teledermatology. , 2005, Archives of dermatology.

[7]  R. Turrisi,et al.  Thoroughness of skin examination by melanoma patients: Influence of age, sex and partner , 2009, The Australasian journal of dermatology.

[8]  H. Soyer,et al.  Recent advances in diagnosing cutaneous melanomas , 2010, F1000 medicine reports.

[9]  D. Fergusson,et al.  Canaries in the Mineshaft: The Dermatology Workforce Shortage in Eastern Ontario , 2008, Journal of cutaneous medicine and surgery.

[10]  L J Schouten,et al.  False-negative findings in skin cancer and melanoma screening. , 1995, Journal of the American Academy of Dermatology.

[11]  J. Aitken,et al.  Increase in skin cancer screening during a community‐based randomized intervention trial , 2006, International journal of cancer.

[12]  A. Marghoob,et al.  Dermoscopy in skin self-examination: A useful tool for select patients. , 2011, Archives of dermatology.

[13]  Robin B. Harris,et al.  Can internet-based continuing medical education improve physicians’ skin cancer knowledge and skills? , 2001 .

[14]  P. Helsing,et al.  Small diameter melanoma: a follow‐up of the Norwegian Melanoma Project , 2004, The British journal of dermatology.

[15]  E. Hibler,et al.  An Internet-delivered video intervention for skin self-examination by patients with melanoma. , 2010, Archives of dermatology.

[16]  R. Drugge,et al.  Melanoma screening with serial whole body photographic change detection using Melanoscan technology. , 2009, Dermatology online journal.

[17]  Robin B Harris,et al.  Thorough skin self-examination in patients with melanoma. , 2006, Oncology nursing forum.

[18]  A. Kopf,et al.  ABCDE--an evolving concept in the early detection of melanoma. , 2005, Archives of dermatology.

[19]  M. Cockburn,et al.  Efficacy of skin self‐examination for the early detection of melanoma , 2010, International journal of dermatology.

[20]  P. Christos,et al.  A survey of skin cancer screening in the primary care setting: a comparison with other cancer screenings. , 2000, Archives of family medicine.

[21]  S. Menzies,et al.  Time to Diagnosis of Melanoma: Same Trend in Different Continents , 2007, Journal of cutaneous medicine and surgery.

[22]  S. Menzies,et al.  Dermoscopy compared with naked eye examination for the diagnosis of primary melanoma: a meta‐analysis of studies performed in a clinical setting , 2008, The British journal of dermatology.

[23]  Pietro Rubegni,et al.  Impact of digital dermoscopy analysis on the decision to follow up or to excise a pigmented skin lesion: a multicentre study , 2011, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[24]  P. Murchie,et al.  Pigmented lesions, cutaneous melanoma, and future challenges for primary care , 2007, The European journal of general practice.

[25]  M. Cockburn,et al.  Prevalence and predictors of skin self‐examination: prospects for melanoma prevention and early detection , 2008, International journal of dermatology.

[26]  D. Polsky,et al.  Noninvasive genomic detection of melanoma , 2011, The British journal of dermatology.

[27]  P. Aegerter,et al.  Is dermoscopy (epiluminescence microscopy) useful for the diagnosis of melanoma? Results of a meta-analysis using techniques adapted to the evaluation of diagnostic tests. , 2001, Archives of dermatology.

[28]  D. English,et al.  Presentation and detection of invasive melanoma in a high-risk population. , 2006, Journal of the American Academy of Dermatology.

[29]  J. Aitken,et al.  Body‐site distribution of skin cancer, pre‐malignant and common benign pigmented lesions excised in general practice , 2011, The British journal of dermatology.

[30]  J. Resneck,et al.  Who else is providing care in dermatology practices? Trends in the use of nonphysician clinicians. , 2008, Journal of the American Academy of Dermatology.

[31]  D. Federman,et al.  Skin cancer screening in primary care: prevalence and barriers. , 1999, Journal of the American Academy of Dermatology.

[32]  C. Curiel-Lewandrowski,et al.  A systematic review of advanced practice nurses’ skin cancer assessment barriers, skin lesion recognition skills, and skin cancer training activities , 2011, Journal of the American Academy of Nurse Practitioners.

[33]  Cesare Massone,et al.  Dermoscopy for skin cancer detection , 2005, Current opinion in oncology.

[34]  A. Halpern,et al.  Psychosocial Mediators of a Nurse Intervention to Increase Skin Self-examination in Patients at High Risk for Melanoma , 2006, Cancer Epidemiology Biomarkers & Prevention.

[35]  M Rademaker,et al.  Successful triage of patients referred to a skin lesion clinic using teledermoscopy (IMAGE IT trial) , 2009, The British journal of dermatology.

[36]  D. Gutkowicz–Krusin,et al.  Comparison of diagnostic and management sensitivity to melanoma between dermatologists and MelaFind: a pilot study. , 2012, Archives of dermatology.

[37]  G. Fabbrocini,et al.  Teledermatology: From Prevention to Diagnosis of Nonmelanoma and Melanoma Skin Cancer , 2011, International journal of telemedicine and applications.

[38]  S. Menzies,et al.  A randomised trial of skin photography as an aid to screening skin lesions in older males , 2002, Journal of medical screening.

[39]  J. Aitken,et al.  Do Centralised Skin Screening Clinics Increase Participation in Melanoma Screening (Australia)? , 2006, Cancer Causes & Control.

[40]  C. Begg,et al.  Screening for cutaneous melanoma by skin self-examination. , 1996, Journal of the National Cancer Institute.

[41]  Emir Veledar,et al.  The impact of total body photography on biopsy rate in patients from a pigmented lesion clinic. , 2007, Journal of the American Academy of Dermatology.

[42]  R. Hofmann-Wellenhof,et al.  The AC Rule for melanoma: a simpler tool for the wider community. , 2011, Journal of the American Academy of Dermatology.

[43]  F. Sera,et al.  The spectrum of dermatoscopic patterns in blue nevi. , 2012, Journal of the American Academy of Dermatology.

[44]  Harald Kittler,et al.  Diagnostic accuracy of dermatoscopy for melanocytic and nonmelanocytic pigmented lesions. , 2011, Journal of the American Academy of Dermatology.

[45]  J. Gershenwald,et al.  Update on the melanoma staging system: The importance of sentinel node staging and primary tumor mitotic rate , 2011, Journal of surgical oncology.

[46]  Josep Malvehy,et al.  Time required for a complete skin examination with and without dermoscopy: a prospective, randomized multicenter study. , 2008, Archives of dermatology.

[47]  D. English,et al.  Clinical pathways to diagnose melanoma: a population-based study , 2007, Melanoma research.

[48]  P. Carli,et al.  Dermatologist detection and skin self-examination are associated with thinner melanomas: results from a survey of the Italian Multidisciplinary Group on Melanoma. , 2003, Archives of dermatology.

[49]  C. Begg,et al.  Sun protection and skin self‐examination in melanoma survivors , 2009, Psycho-oncology.

[50]  Rosemarie A. Martin,et al.  Melanoma early detection with thorough skin self-examination: the "Check It Out" randomized trial. , 2007, American journal of preventive medicine.

[51]  A. Halpern,et al.  Overcoming obstacles to skin cancer examinations and prevention counseling for high-risk patients: results of a national survey of primary care physicians. , 2004, The Journal of the American Board of Family Practice.

[52]  Daniela Massi,et al.  Dermoscopy improves accuracy of primary care physicians to triage lesions suggestive of skin cancer. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[53]  Rainer Hofmann-Wellenhof,et al.  Melanoma Screening with Cellular Phones , 2007, PloS one.

[54]  D. English,et al.  Incidence of new and changed nevi and melanomas detected using baseline images and dermoscopy in patients at high risk for melanoma. , 2005, Archives of dermatology.

[55]  G. Searles,et al.  The Amazing Vanishing Canadian Dermatologist: Results from the 2006 Canadian Dermatology Association Member Survey , 2010, Journal of cutaneous medicine and surgery.

[56]  E. Warshaw,et al.  Diagnosing and managing cutaneous pigmented lesions: Primary care physicians versus dermatologists , 2006, Journal of General Internal Medicine.

[57]  P. Baade,et al.  Impact of a video-based intervention to improve the prevalence of skin self-examination in men 50 years or older: the randomized skin awareness trial. , 2011, Archives of dermatology.

[58]  R. MacKie,et al.  Effect of public education aimed at early diagnosis of malignant melanoma: cohort comparison study , 2003, BMJ : British Medical Journal.

[59]  S. Manne,et al.  Prevalence and Correlates of Sun Protection and Skin Self-Examination Practices Among Cutaneous Malignant Melanoma Survivors , 2006, Journal of Behavioral Medicine.

[60]  Giuseppe Argenziano,et al.  Using dermoscopic criteria and patient-related factors for the management of pigmented melanocytic nevi. , 2009, Archives of dermatology.

[61]  R. Braun,et al.  Telemedical wound care using a new generation of mobile telephones: a feasibility study. , 2005, Archives of dermatology.

[62]  S. Soong,et al.  Detection of First Relapse in Cutaneous Melanoma Patients: Implications for the Formulation of Evidence-Based Follow-up Guidelines , 2007, Annals of Surgical Oncology.

[63]  D. English,et al.  Clinical whole‐body skin examination reduces the incidence of thick melanomas , 2009, International journal of cancer.

[64]  Rainer Hofmann-Wellenhof,et al.  Teledermatology: an update. , 2008, Seminars in cutaneous medicine and surgery.

[65]  Monika Janda,et al.  Enhanced skin self-examination: a novel approach to skin cancer monitoring and follow-up. , 2013, JAMA dermatology.

[66]  L. Ferris,et al.  New diagnostic aids for melanoma. , 2012, Dermatologic clinics.

[67]  Cesare Massone,et al.  Mobile teledermoscopy--melanoma diagnosis by one click? , 2009, Seminars in cutaneous medicine and surgery.

[68]  P. Carli,et al.  Results of surveillance programme aimed at early diagnosis of cutaneous melanoma in high risk Mediterranean subjects. , 2003, European journal of dermatology : EJD.

[69]  J. Aitken,et al.  Diagnosing skin cancer in primary care: how do mainstream general practitioners compare with primary care skin cancer clinic doctors? , 2007, The Medical journal of Australia.

[70]  H. de Vries,et al.  Skin self-examination of persons from families with familial atypical multiple mole melanoma (FAMMM). , 2009, Patient education and counseling.

[71]  Clara Curiel-Lewandrowski,et al.  Barriers to mobile teledermoscopy in primary care. , 2013, Journal of the American Academy of Dermatology.

[72]  H. Soyer,et al.  Teledermatology: Just Cool or a Real Tool? , 2005, Dermatology.

[73]  M. Weinstock,et al.  Does skin cancer screening save lives? , 2012, Cancer.

[74]  C Massone,et al.  Teledermoscopy: education, discussion forums, teleconsulting and mobile teledermoscopy. , 2010, Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia.

[75]  H. Peter Soyer,et al.  Actinic Keratosis, Basal Cell Carcinoma and Squamous Cell Carcinoma , 2012 .

[76]  D. Moore,et al.  Screening program reduced melanoma mortality at the Lawrence Livermore National Laboratory, 1984 to 1996. , 2006, Journal of the American Academy of Dermatology.

[77]  Elizabeth Won,et al.  The use of mole-mapping diagrams to increase skin self-examination accuracy. , 2006, Journal of the American Academy of Dermatology.

[78]  R. Hofmann-Wellenhof,et al.  Mobile teledermatology for skin tumour screening: diagnostic accuracy of clinical and dermoscopic image tele‐evaluation using cellular phones , 2011, The British journal of dermatology.

[79]  J. Kvedar,et al.  Staying on top in dermatology: why we must act now to address the capacity challenge. , 2008, Archives of dermatology.

[80]  D. Federman,et al.  Skin cancer screening by dermatologists: prevalence and barriers. , 2002, Journal of the American Academy of Dermatology.

[81]  J. Resneck,et al.  The US dermatology workforce: a specialty remains in shortage. , 2008, Journal of the American Academy of Dermatology.

[82]  Milind Rajadhyaksha,et al.  Differences between polarized light dermoscopy and immersion contact dermoscopy for the evaluation of skin lesions. , 2007, Archives of dermatology.

[83]  F. Powell,et al.  Suspected skin malignancy: a comparison of diagnoses of family practitioners and dermatologists in 493 patients , 2001, International journal of dermatology.

[84]  M. Helfand,et al.  Screening for skin cancer. , 2001, American journal of preventive medicine.

[85]  Rainer Hofmann-Wellenhof,et al.  Reflectance confocal microscopy--state-of-art and research overview. , 2009, Seminars in cutaneous medicine and surgery.

[86]  Peter Elsner,et al.  Electrical impedance spectroscopy and the diagnostic accuracy for malignant melanoma , 2011, Experimental dermatology.

[87]  A. Halpern,et al.  Skin cancer prevention and detection by nurses: attitudes, perceptions, and barriers. , 2004, Journal of cancer education : the official journal of the American Association for Cancer Education.

[88]  J. Malvehy,et al.  Follow-up of melanocytic skin lesions with digital total-body photography and digital dermoscopy: a two-step method. , 2002, Clinics in dermatology.

[89]  June K. Robinson,et al.  Use of photographs illustrating ABCDE criteria in skin self-examination. , 2009, Archives of dermatology.

[90]  Susan M Swetter,et al.  Efficacy of Skin Self-Examination Practices for Early Melanoma Detection , 2009, Cancer Epidemiology, Biomarkers & Prevention.

[91]  Harold S Rabinovitz,et al.  Dermoscopy of pigmented skin lesions. , 2005, Journal of the American Academy of Dermatology.

[92]  M. Mihm,et al.  The performance of MelaFind: a prospective multicenter study. , 2011, Archives of dermatology.

[93]  P. Carli,et al.  Self‐detected cutaneous melanomas in Italian patients , 2004, Clinical and experimental dermatology.

[94]  S. Menzies,et al.  Impact of dermoscopy and short‐term sequential digital dermoscopy imaging for the management of pigmented lesions in primary care: a sequential intervention trial , 2009, The British journal of dermatology.

[95]  J. Wolf,et al.  Diagnostic inaccuracy of smartphone applications for melanoma detection. , 2013, JAMA dermatology.

[96]  U. P. S. T. Force,et al.  Screening for skin cancer: U.S. Preventive Services Task Force recommendation statement. , 2009 .

[97]  D. Federman,et al.  Screening for skin cancer in primary care settings. , 1997, Archives of dermatology.

[98]  A. Halpern,et al.  Use of nonphysician health care providers for skin cancer screening in the primary care setting. , 2002, Preventive medicine.

[99]  A. Rhodes.  Cutaneous melanoma and intervention strategies to reduce tumor‐related mortality: what we know, what we don't know, and what we think we know that isn't so , 2006, Dermatologic therapy.

[100]  Timothy A. Dall,et al.  The burden of skin diseases: 2004 a joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology. , 2006, Journal of the American Academy of Dermatology.

[101]  S. Gruber,et al.  Is physician detection associated with thinner melanomas? , 1999, JAMA.

[102]  L. Nekhlyudov,et al.  The interface of primary and oncology specialty care: from symptoms to diagnosis. , 2010, Journal of the National Cancer Institute. Monographs.