Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 2. Prediction of blood-brain barrier penetration.
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[1] J. Scherrmann,et al. Simultaneous microdialysis in brain and blood of the mouse: extracellular and intracellular brain colchicine disposition , 1998, Brain Research.
[2] Philip L. Smith,et al. In vitro models to predict blood-brain barrier permeability , 1997 .
[3] D D Breimer,et al. The blood-brain barrier in neuroinflammatory diseases. , 1997, Pharmacological reviews.
[4] H Lennernäs,et al. Human Jejunal Effective Permeability and Its Correlation with Preclinical Drug Absorption Models , 1997, The Journal of pharmacy and pharmacology.
[5] Harpreet S. Chadha,et al. Hydrogen bonding. 33. Factors that influence the distribution of solutes between blood and brain. , 1994, Journal of pharmaceutical sciences.
[6] David D. Christ,et al. Chapter 33. Plasma Protein Binding of Drugs , 1996 .
[7] U Norinder,et al. Theoretical calculation and prediction of brain-blood partitioning of organic solutes using MolSurf parametrization and PLS statistics. , 1998, Journal of pharmaceutical sciences.
[8] R Griffiths,et al. Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists. , 1988, Journal of medicinal chemistry.
[9] P D Leeson,et al. Effect of plasma protein binding on in vivo activity and brain penetration of glycine/NMDA receptor antagonists. , 1997, Journal of medicinal chemistry.
[10] Harpreet S. Chadha,et al. Hydrogen-bonding. Part 36. Determination of blood brain distribution using octanol-water partition coefficients. , 1995, Drug design and discovery.
[11] Harpreet S. Chadha,et al. Molecular Factors Influencing Drug Transfer across the Blood‐Brain Barrier , 1997, The Journal of pharmacy and pharmacology.
[12] F. Lombardo,et al. Computation of brain-blood partitioning of organic solutes via free energy calculations. , 1996, Journal of medicinal chemistry.
[13] J R Chretien,et al. Estimation of blood-brain barrier crossing of drugs using molecular size and shape, and H-bonding descriptors. , 1998, Journal of drug targeting.
[14] D. E. Clark. Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 1. Prediction of intestinal absorption. , 1999, Journal of pharmaceutical sciences.
[15] C R Ganellin,et al. Predicting the brain-penetrating capability of histaminergic compounds. , 1994, Drug design and discovery.
[16] M. Abraham,et al. On the partition of ampholytes: application to blood-brain distribution. , 1997, Journal of pharmaceutical sciences.
[17] M. Abraham,et al. The use of characteristic volumes to measure cavity terms in reversed phase liquid chromatography , 1987 .
[18] David J. Livingstone,et al. Data analysis for chemists , 1995 .
[19] Donald G. Truhlar,et al. omnisol: Fast Prediction of Free Energies of Solvation and Partition Coefficients , 1998 .
[20] F. Lombardo,et al. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings , 1997 .
[21] S. Hirono,et al. Simple Method of Calculating Octanol/Water Partition Coefficient. , 1992 .
[22] W. Pardridge,et al. CNS Drug Design Based on Principles of Blood‐Brain Barrier Transport , 1998, Journal of neurochemistry.
[23] M. Kansy,et al. Hydrogen-Bonding Capacity and Brain Penetration , 1992, Chimia (Basel).