Pioglitazone reduces epicardial fat and improves diastolic function in patients with type 2 diabetes
暂无分享,去创建一个
P. Iozzo | R. DeFronzo | A. Gastaldelli | M. Abdul-Ghani | C. Solis-Herrera | E. Cersosimo | R. Chilton | G. Clarke | Aurora Merovci | Marjorie Molina-Wilkins | Alexander Moody | A. Moody | Carolina Solis-Herrera
[1] M. Chiriacò,et al. Epicardial adipose tissue thickness is associated with reduced peak oxygen consumption and systolic reserve in patients with type 2 diabetes and normal heart function , 2022, Diabetes, obesity & metabolism.
[2] A. Mengozzi,et al. Rethinking pioglitazone as a cardioprotective agent: a new perspective on an overlooked drug , 2021, Cardiovascular Diabetology.
[3] M. Jensen,et al. Epicardial adipose tissue predicts incident cardiovascular disease and mortality in patients with type 2 diabetes , 2019, Cardiovascular Diabetology.
[4] P. Schnohr,et al. Epicardial and pericardial adipose tissues are associated with reduced diastolic and systolic function in type 2 diabetes , 2019, Diabetes, obesity & metabolism.
[5] R. DeFronzo,et al. Pioglitazone: The forgotten, cost-effective cardioprotective drug for type 2 diabetes , 2019, Diabetes & vascular disease research.
[6] Jeroen J. Bax,et al. Impact of Epicardial Adipose Tissue, Left Ventricular Myocardial Fat Content, and Interstitial Fibrosis on Myocardial Contractile Function , 2018, Circulation. Cardiovascular imaging.
[7] R. DeFronzo,et al. Impaired left ventricular diastolic function in T2DM patients is closely related to glycemic control , 2018, Endocrinology, diabetes & metabolism.
[8] Rachael Williams,et al. Pioglitazone and cause-specific risk of mortality in patients with type 2 diabetes: extended analysis from a European multidatabase cohort study , 2018, BMJ Open Diabetes Research & Care.
[9] Y. van der Graaf,et al. Pioglitazone and the secondary prevention of cardiovascular disease. A meta-analysis of randomized-controlled trials , 2017, Cardiovascular Diabetology.
[10] P. Iozzo,et al. Pioglitazone Improves Left Ventricular Diastolic Function in Subjects With Diabetes , 2017, Diabetes Care.
[11] P. Sbraccia,et al. Epicardial adipose tissue: at the heart of the obesity complications , 2017, Acta Diabetologica.
[12] C. Viscoli,et al. Pioglitazone after Ischemic Stroke or Transient Ischemic Attack. , 2016, The New England journal of medicine.
[13] S. Rabkin. The relationship between epicardial fat and indices of obesity and the metabolic syndrome: a systematic review and meta-analysis. , 2014, Metabolic syndrome and related disorders.
[14] J. M. Suh,et al. PPARγ signaling and metabolism: the good, the bad and the future , 2013, Nature Medicine.
[15] P. Marraccini,et al. The role of cardiac fat in insulin resistance , 2012, Current opinion in clinical nutrition and metabolic care.
[16] Eugenio Picano,et al. Pericardial rather than epicardial fat is a cardiometabolic risk marker: an MRI vs echo study. , 2011, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.
[17] D. Dey,et al. Increase in epicardial fat volume is associated with greater coronary artery calcification progression in subjects at intermediate risk by coronary calcium score: a serial study using non-contrast cardiac CT. , 2011, Atherosclerosis.
[18] Devjit Tripathy,et al. Pioglitazone for diabetes prevention in impaired glucose tolerance. , 2011, The New England journal of medicine.
[19] S. Bahouth,et al. Inflammatory Genes in Epicardial Fat Contiguous With Coronary Atherosclerosis in the Metabolic Syndrome and Type 2 Diabetes , 2011, Diabetes Care.
[20] R. DeFronzo. Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009 , 2010, Diabetologia.
[21] L. J. Hardies,et al. Effects of pioglitazone on intramyocellular fat metabolism in patients with type 2 diabetes mellitus. , 2010, The Journal of clinical endocrinology and metabolism.
[22] E. Ferrannini,et al. Decreased whole body lipolysis as a mechanism of the lipid-lowering effect of pioglitazone in type 2 diabetic patients. , 2009, American journal of physiology. Endocrinology and metabolism.
[23] Jeroen J. Bax,et al. Pioglitazone Improves Cardiac Function and Alters Myocardial Substrate Metabolism Without Affecting Cardiac Triglyceride Accumulation and High-Energy Phosphate Metabolism in Patients With Well-Controlled Type 2 Diabetes Mellitus , 2009, Circulation.
[24] Udo Hoffmann,et al. Pericardial Fat, Intrathoracic Fat, and Measures of Left Ventricular Structure and Function: The Framingham Heart Study , 2009, Circulation.
[25] M. Prentki,et al. Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial , 2009, Diabetologia.
[26] Udo Hoffmann,et al. Association of pericardial fat, intrathoracic fat, and visceral abdominal fat with cardiovascular disease burden: the Framingham Heart Study. , 2008, European heart journal.
[27] Y. Miyazaki,et al. Rosiglitazone and pioglitazone similarly improve insulin sensitivity and secretion, glucose tolerance and adipocytokines in type 2 diabetic patients , 2008, Diabetes, obesity & metabolism.
[28] Mathias Prokop,et al. Relation of epicardial and pericoronary fat to coronary atherosclerosis and coronary artery calcium in patients undergoing coronary angiography. , 2008, The American journal of cardiology.
[29] Udo Hoffmann,et al. Pericardial Fat, Visceral Abdominal Fat, Cardiovascular Disease Risk Factors, and Vascular Calcification in a Community-Based Sample: The Framingham Heart Study , 2008, Circulation.
[30] E. Abel,et al. Diabetic cardiomyopathy revisited. , 2007, Circulation.
[31] H. Sacks,et al. Human epicardial adipose tissue: a review. , 2007, American heart journal.
[32] L. J. Hardies,et al. Effects of peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ agonists on glucose and lipid metabolism in patients with type 2 diabetes mellitus , 2007, Diabetologia.
[33] J. Hardies,et al. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. , 2006, The New England journal of medicine.
[34] P. Iozzo,et al. Myocardial triglyceride content and epicardial fat mass in human obesity: relationship to left ventricular function and serum free fatty acid levels. , 2006, The Journal of clinical endocrinology and metabolism.
[35] Y. Miyazaki,et al. The Effect of Pioglitazone on the Liver , 2006, Diabetes Care.
[36] F. Leonetti,et al. Epicardial adipose tissue and insulin resistance in obese subjects. , 2005, The Journal of clinical endocrinology and metabolism.
[37] Erland Erdmann,et al. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial , 2005, The Lancet.
[38] R. DeFronzo,et al. Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach. , 2004, The Journal of clinical endocrinology and metabolism.
[39] F. Leonetti,et al. Echocardiographic epicardial adipose tissue is related to anthropometric and clinical parameters of metabolic syndrome: a new indicator of cardiovascular risk. , 2003, The Journal of clinical endocrinology and metabolism.
[40] A. Butte,et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1 , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[41] Z. Bloomgarden. Obesity, hypertension, and insulin resistance. , 2002, Diabetes care.
[42] J. Hardies,et al. Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients. , 2002, The Journal of clinical endocrinology and metabolism.
[43] M. Matsuda,et al. Improved glycemic control and enhanced insulin sensitivity in type 2 diabetic subjects treated with pioglitazone. , 2001, Diabetes care.
[44] 任艳,et al. 胰岛素增敏剂一Thiazolidinediones研究现状 , 2000 .
[45] R. DeFronzo,et al. Glucose clamp technique: a method for quantifying insulin secretion and resistance. , 1979, The American journal of physiology.
[46] C. Morales,et al. Epicardial Adipose Tissue in Cardiovascular Disease. , 2019, Advances in experimental medicine and biology.
[47] P. Toth. The association of pericardial fat with incident coronary heart disease: the Multi-Ethnic Study of Atherosclerosis (MESA) , 2010 .
[48] Jeroen J. Bax,et al. Pioglitazone compared with metformin increases pericardial fat volume in patients with type 2 diabetes mellitus. , 2010, The Journal of clinical endocrinology and metabolism.
[49] R. Mosteller. Simplified calculation of body-surface area. , 1987, The New England journal of medicine.