S/e-PTFE episcleral buckling implants: an experimental and histopathologic study.

To investigate tissue changes induced by the implantation of a silicone band coated with expanded polytetrafluoroethylene (S/e-PTFE) used as scleral buckling, an experimental and histopathological study was performed in rabbits. The right eyes of eight rabbits were implanted for 28-85 days with S/e-PTFE. No complications were encountered in any of the eyes, so histopathological examinations could be performed. Encapsulations combined with numerous giant cells were found to be surrounding the implants in seven eyes, and deposits from the mineral salts of calcium were found in three eyes, forming granulomas possibly caused by irregularities of the implant surface. The porous structure allowed a peripheral colonization by fibrovascular tissue. Taking into account the histological results, the use of this material does not appear suitable. However, this inflammation was limited and did not merge on surrounding tissues.

[1]  R. Michels,et al.  SCLERAL BUCKLING METHODS FOR RHEGMATOGENOUS RETINAL DETACHMENT , 1986, Retina.

[2]  M. Refojo,et al.  HYDROGEL IMPLANT FOR SCLERAL BUCKLING: Long-term Observations , 1985, Retina.

[3]  J. Bellón,et al.  Similarity in behavior of polytetrafluoroethylene (ePTFE) prostheses implanted into different interfaces. , 1996, Journal of biomedical materials research.

[4]  M. Refojo,et al.  HYDROPHILIC ACRYLATE SCLERAL BUCKLING IMPLANTS IN RABBITS: Long-term Clinicopathologic Observations , 1983 .

[5]  G A Ksander,et al.  STUDY OF ENCAPSULATION OF SILICONE RUBBER IMPLANTS IN ANIMALS A Foreign‐Body Reaction , 1978, Plastic and reconstructive surgery.

[6]  A. Behar,et al.  HISTOPATHOLOGIC FINDINGS FOLLOWING SCLERAL BUCKLING IN AN EYE 18 DAYS AFTER A CIRCLING-BUCKLING OPERATION WITH POLYETHYLENE TUBE WITH PARTICULAR REFERENCE TO THE AREA WHERE THE POLYETHYLENE TUBE INDENTED UNRESECTED AND UNDIATHERMIZED SCLERA. , 1964, American journal of ophthalmology.

[7]  N. Ziats,et al.  In vitro and in vivo interactions of cells with biomaterials. , 1988, Biomaterials.

[8]  D Chauvaud,et al.  e-PTFE as scleral buckling episcleral implants: an experimental and histopathologic study. , 1999, Journal of biomedical materials research.

[9]  P G Rehkopf,et al.  Polytetrafluoroethylene in experimental retinal detachment surgery. , 1981, Annals of ophthalmology.

[10]  G. Renard,et al.  Expanded Polytetrafluoroethylene Episcleral Implants Used as Encircling Scleral Buckling , 2000, Ophthalmic Research.

[11]  F I Tolentino,et al.  A HYDROPHILIC ACRYLATE IMPLANT FOR SCLERAL BUCKLING: Technique and Clinical Experience , 1981, Retina.

[12]  F I Tolentino,et al.  Long-term complications of the MAI hydrogel intrascleral buckling implant. , 1992, Archives of ophthalmology.

[13]  C L Schepens,et al.  Scleral implants: an historical perspective. , 1991, Survey of ophthalmology.

[14]  C. Barr.  THE HISTOPATHOLOGY OF SUCCESSFUL RETINAL REATTACHMENT , 1990, Retina.

[15]  L. D’Urso,et al.  Polytetrafluoroethylene giant granuloma and adenopathy: long-term complications following subureteral polytetrafluoroethylene injection for the treatment of vesicoureteral reflux in children. , 1997, The Journal of urology.

[16]  J. Korobelnik,et al.  MIRAGEL VERSUS SILASTIC USED AS EPISCLERAL IMPLANTS IN RABBITS; An Experimental and Histopathologic Comparative Study , 1995, Retina.

[17]  M. Refojo,et al.  Poly(methyl acrylate-co-hydroxyethyl acrylate) hydrogel implant material of strength and softness. , 1981, Journal of biomedical materials research.

[18]  C. Nathan,et al.  Secretory products of macrophages. , 1987, The Journal of clinical investigation.

[19]  A DELLAPORTA,et al.  Experimental studies on a scleral buckling operation. , 1956, American journal of ophthalmology.

[20]  Y Pouliquen,et al.  Encapsulation of scleral buckling materials. A study of sixty specimens. , 1998, Ophthalmology.