Stroke: Morbidity, Risk Factors, and Care in Taiwan

Stroke is the third leading cause of death and the most common cause of complex disability in Taiwan. The annual age-standardized mortality rate of stroke is steadily decreasing between 2001 and 2012. The average years of potential life lost before age 70 for stroke is 13.8 years, ranked the fifth in the cause of death. Its national impact is predicted to be greater accompany aging population. The most common type of stroke was ischemic stroke in Taiwan. Small vessel occlusion was the majority of ischemic strokes subtype. Age, gender, hypertension, diabetes hyperlipidemia, obesity, atrial fibrillation, and smoking were important contributory factors to stroke morbidity. The standard treatment for acute ischemic stroke in Taiwan is providing the intravenous thrombolysis with recombinant tissue plasminogen activator (IV tPA) therapy for ischemic stroke patients within 3 hours of symptom onset. However, the rate of IV tPA therapy for patients with acute ischemic stroke is still low in Taiwan. Therefore, improving the public awareness of stroke warning signs and act on stroke and improving in-hospital critical pathway for thrombolysis would be the most important and urgent issues in Taiwan. To improve acute stroke care quality, a program of Breakthrough Series-Stroke activity was conducted from 2010 to 2011 and stroke centers were established in the medical centers. For the prevention of stroke, it was successful to increased annual smoke cessation rate through the 2009 Tobacco Hazards Prevention Act and decreased obesity rate through a nationwide weight-loss program conducted by Health Promotion Administration from 2011 to 2013 in Taiwan.

[1]  Tzeng-Ji Chen,et al.  Metformin-inclusive therapy reduces the risk of stroke in patients with diabetes: a 4-year follow-up study. , 2014, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

[2]  Tzeng-Ji Chen,et al.  The beneficial effects of statins in patients undergoing hemodialysis. , 2013, International journal of cardiology.

[3]  P. Lin,et al.  Dietary intakes consistent with the DASH dietary pattern reduce blood pressure increase with age and risk for stroke in a Chinese population. , 2013, Asia Pacific journal of clinical nutrition.

[4]  T. Chao,et al.  Atrial Fibrillation and the Risk of Ischemic Stroke: Does It Still Matter in Patients With a CHA2DS2-VASc Score of 0 or 1? , 2012, Stroke.

[5]  C. Chen,et al.  Stock or stroke? Stock market movement and stroke incidence in Taiwan , 2012, Social Science & Medicine.

[6]  T. Peng,et al.  The impact of smoking on the severity of acute ischemic stroke , 2011, Journal of the Neurological Sciences.

[7]  Lian-Yu Lin,et al.  Risk factors and incidence of ischemic stroke in Taiwanese with nonvalvular atrial fibrillation-- a nation wide database analysis. , 2011, Atherosclerosis.

[8]  Hsing-Yi Chang,et al.  Time trend of obesity, the metabolic syndrome and related dietary pattern in Taiwan: from NAHSIT 1993-1996 to NAHSIT 2005-2008. , 2011, Asia Pacific journal of clinical nutrition.

[9]  Chung Y. Hsu,et al.  Hypertensive Disorders in Pregnancy and Preterm Delivery and Subsequent Stroke in Asian Women: A Retrospective Cohort Study , 2011, Stroke.

[10]  Jiann-Der Lee,et al.  Stroke risk factors and subtypes in different age groups: a hospital-based study. , 2010, Neurology India.

[11]  J. Jeng,et al.  Get With The Guidelines-Stroke Performance Indicators: Surveillance of Stroke Care in the Taiwan Stroke Registry: Get With The Guidelines-Stroke in Taiwan , 2010, Circulation.

[12]  K. Chien,et al.  Atrial fibrillation prevalence, incidence and risk of stroke and all-cause death among Chinese. , 2010, International journal of cardiology.

[13]  Weiping Jia,et al.  Diabetes in Asia: epidemiology, risk factors, and pathophysiology. , 2009, JAMA.

[14]  Shiao-lin Lai,et al.  Risk Factors and Subtype Analysis of Acute Ischemic Stroke , 2008, European Neurology.

[15]  R Peto,et al.  Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis. , 2008, Lancet.

[16]  Herng‐Ching Lin,et al.  Urbanization and Stroke Prevalence in Taiwan: Analysis of a Nationwide Survey , 2007, Journal of Urban Health.

[17]  Tsong-Hai Lee,et al.  First-Ever Ischemic Stroke in Very Old Asians: Clinical Features, Stroke Subtypes, Risk Factors and Outcome , 2007, European Neurology.

[18]  C. Bai,et al.  Influence of Metabolic Syndrome and General Obesity on the Risk of Ischemic Stroke , 2006, Stroke.

[19]  G. Lip,et al.  Prognostic Value of Plasma von Willebrand Factor and Soluble P-Selectin as Indices of Endothelial Damage and Platelet Activation in 994 Patients With Nonvalvular Atrial Fibrillation , 2003, Circulation.

[20]  Tsong-Hai Lee,et al.  Etiologic Study of Young Ischemic Stroke in Taiwan , 2002, Stroke.

[21]  P. Deurenberg,et al.  Asians are different from Caucasians and from each other in their body mass index/body fat per cent relationship , 2002, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[22]  J. Fuh,et al.  Incidence of Stroke on Kinmen, Taiwan , 2000, Neuroepidemiology.

[23]  T. Chiang,et al.  Stroke prevalence in Taiwan. Findings from the 1994 National Health Interview Survey. , 1997, Stroke.

[24]  Zei-ShungHuang,et al.  Stroke Prevalence in Taiwan , 1997 .

[25]  H. W. Liu,et al.  Impact of alcohol consumption and cigarette smoking on stroke among the elderly in Taiwan. , 1995, Stroke.

[26]  David Lee Gordon,et al.  Classification of Subtype of Acute Ischemic Stroke: Definitions for Use in a Multicenter Clinical Trial , 1993, Stroke.

[27]  C. Lan,et al.  Incidence of Stroke in Taiwan , 1992, Stroke.

[28]  C. Lan,et al.  Prevalence of stroke in Taiwan. , 1989, Stroke.

[29]  A. Alberts,et al.  Discovery, biochemistry and biology of lovastatin. , 1988, The American journal of cardiology.

[30]  T. James,et al.  Global Prevalence of Adult Obesity , 2015 .

[31]  H. Sung,et al.  Impact of the 2009 Taiwan tobacco hazards prevention act on smoking cessation. , 2014, Addiction.