The stromal cell-surface protease fibroblast activation protein-α localizes to lipid rafts and is recruited to invadopodia.
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[1] T. Salo,et al. Caveolin-1 accumulation in the tongue cancer tumor microenvironment is significantly associated with poor prognosis: an in-vivo and in-vitro study , 2015, BMC Cancer.
[2] V. Zoete,et al. The CAP1/Prss8 catalytic triad is not involved in PAR2 activation and protease nexin‐1 (PN‐1) inhibition , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[3] J. Yang,et al. Invading one step at a time: the role of invadopodia in tumor metastasis , 2014, Oncogene.
[4] F. Nestle,et al. Diverse matrix metalloproteinase functions regulate cancer amoeboid migration , 2014, Nature Communications.
[5] O. Schilling,et al. Understanding fibroblast activation protein (FAP): Substrates, activities, expression and targeting for cancer therapy , 2014, Proteomics. Clinical applications.
[6] T. Bugge,et al. The Membrane-anchored Serine Protease Prostasin (CAP1/PRSS8) Supports Epidermal Development and Postnatal Homeostasis Independent of Its Enzymatic Activity* , 2014, The Journal of Biological Chemistry.
[7] H. J. Kim,et al. Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts , 2014, Oncogene.
[8] P. Insel,et al. Interaction of membrane/lipid rafts with the cytoskeleton: impact on signaling and function: membrane/lipid rafts, mediators of cytoskeletal arrangement and cell signaling. , 2014, Biochimica et biophysica acta.
[9] Feng Yu,et al. A Vaccine That Co-Targets Tumor Cells and Cancer Associated Fibroblasts Results in Enhanced Antitumor Activity by Inducing Antigen Spreading , 2013, PloS one.
[10] Hong-mei Wu,et al. Effects of the fibroblast activation protein on the invasion and migration of gastric cancer. , 2013, Experimental and molecular pathology.
[11] M. Junttila,et al. Influence of tumour micro-environment heterogeneity on therapeutic response , 2013, Nature.
[12] T. Thompson,et al. Loss of caveolin‐1 in prostate cancer stroma correlates with reduced relapse‐free survival and is functionally relevant to tumour progression , 2013, The Journal of pathology.
[13] Zonghuan Li,et al. Caveolin-1 Expression Level in Cancer Associated Fibroblasts Predicts Outcome in Gastric Cancer , 2013, PloS one.
[14] W. Cho,et al. Quantum Dots-Based Immunofluorescent Imaging of Stromal Fibroblasts Caveolin-1 and Light Chain 3B Expression and Identification of Their Clinical Significance in Human Gastric Cancer , 2012, International journal of molecular sciences.
[15] D. Rigden,et al. Evaluating Caveolin Interactions: Do Proteins Interact with the Caveolin Scaffolding Domain through a Widespread Aromatic Residue-Rich Motif? , 2012, PloS one.
[16] J. Isaacs,et al. Targeting carcinoma-associated fibroblasts within the tumor stroma with a fibroblast activation protein-activated prodrug. , 2012, Journal of the National Cancer Institute.
[17] Hong-mei Wu,et al. Roles of fibroblasts from the interface zone in invasion, migration, proliferation and apoptosis of gastric adenocarcinoma , 2012, Journal of Clinical Pathology.
[18] L. Coussens,et al. Accessories to the crime: functions of cells recruited to the tumor microenvironment. , 2012, Cancer cell.
[19] Kai Simons,et al. Membrane organization and lipid rafts. , 2011, Cold Spring Harbor perspectives in biology.
[20] James O. Jones,et al. Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein–α , 2010, Science.
[21] N. Cho,et al. Stromal fibroblasts from the interface zone of human breast carcinomas induce an epithelial–mesenchymal transition-like state in breast cancer cells in vitro , 2010, Journal of Cell Science.
[22] E. Puré,et al. Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice. , 2009, The Journal of clinical investigation.
[23] F. Sotgia,et al. An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease spread and epithelial Akt activation , 2009, Cell cycle.
[24] Paul A Insel,et al. Lipid rafts and caveolae and their role in compartmentation of redox signaling. , 2009, Antioxidants & redox signaling.
[25] J. Trejo,et al. Proteases display biased agonism at protease-activated receptors: location matters! , 2009, Molecular interventions.
[26] J. Pollard,et al. Microenvironmental regulation of metastasis , 2009, Nature Reviews Cancer.
[27] M. Ebert,et al. Caveats of caveolin-1 in cancer progression. , 2008, Cancer letters.
[28] K. Heider,et al. Effective Immunoconjugate Therapy in Cancer Models Targeting a Serine Protease of Tumor Fibroblasts , 2008, Clinical Cancer Research.
[29] S. Wiseman,et al. Caveolin-1 in tumor progression: the good, the bad and the ugly , 2008, Cancer and Metastasis Reviews.
[30] Mario Gimona,et al. Assembly and biological role of podosomes and invadopodia. , 2008, Current opinion in cell biology.
[31] P. McKee,et al. Phase II trial of single agent Val-boroPro (talabostat) inhibiting fibroblast activation protein in patients with metastatic colorectal cancer , 2007, Cancer biology & therapy.
[32] D. Lingwood,et al. Detergent resistance as a tool in membrane research , 2007, Nature Protocols.
[33] S. Robbins,et al. The SPFH domain-containing proteins: more than lipid raft markers. , 2007, Trends in cell biology.
[34] M. Lisanti,et al. Caveolae and caveolin-1: novel potential targets for the treatment of cardiovascular disease. , 2007, Current pharmaceutical design.
[35] C. Morimoto,et al. Caveolin-1 Triggers T-cell Activation via CD26 in Association with CARMA1* , 2007, Journal of Biological Chemistry.
[36] M. Mann,et al. In-gel digestion for mass spectrometric characterization of proteins and proteomes , 2006, Nature Protocols.
[37] M. Mann,et al. Protein interaction screening by quantitative immunoprecipitation combined with knockdown (QUICK) , 2006, Nature Methods.
[38] Lennart Martens,et al. DBToolkit: processing protein databases for peptide-centric proteomics , 2005, Bioinform..
[39] Robert G Parton,et al. Flotillins and the PHB Domain Protein Family: Rafts, Worms and Anaesthetics , 2005, Traffic.
[40] K. Aertgeerts,et al. Structural and Kinetic Analysis of the Substrate Specificity of Human Fibroblast Activation Protein α* , 2005, Journal of Biological Chemistry.
[41] Chris F. Taylor,et al. A common open representation of mass spectrometry data and its application to proteomics research , 2004, Nature Biotechnology.
[42] S. Iwata,et al. CD26 up-regulates expression of CD86 on antigen-presenting cells by means of caveolin-1. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[43] A. Houghton,et al. FAPα, a surface peptidase expressed during wound healing, is a tumor suppressor , 2004, Oncogene.
[44] Robertson Craig,et al. TANDEM: matching proteins with tandem mass spectra. , 2004, Bioinformatics.
[45] M. Loeffler,et al. An oral vaccine against the tumor-stromal antigen FAP (fibroblast activation protein) inhibits growth of chemo-resistant murine colon-carcinoma , 2004 .
[46] M. Lisanti,et al. The caveolin proteins , 2004, Genome Biology.
[47] R. Aebersold,et al. Automated statistical analysis of protein abundance ratios from data generated by stable-isotope dilution and tandem mass spectrometry. , 2003, Analytical chemistry.
[48] K. Okada,et al. Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer. , 2003, Cancer letters.
[49] P. Gargalovic,et al. Cellular apoptosis is associated with increased caveolin-1 expression in macrophages Published, JLR Papers in Press, June 1, 2003. DOI 10.1194/jlr.M300140-JLR200 , 2003, Journal of Lipid Research.
[50] J. Thyberg. Caveolin-1 and caveolae act as regulators of mitogenic signaling in vascular smooth muscle cells. , 2003, Arteriosclerosis, thrombosis, and vascular biology.
[51] R. Aebersold,et al. A statistical model for identifying proteins by tandem mass spectrometry. , 2003, Analytical chemistry.
[52] M. Mann,et al. Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[53] M. Mann,et al. Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics. , 2003, Analytical chemistry.
[54] Alexey I Nesvizhskii,et al. Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. , 2002, Analytical chemistry.
[55] Nektarios Tavernarakis,et al. The SPFH domain: implicated in regulating targeted protein turnover in stomatins and other membrane-associated proteins. , 1999, Trends in biochemical sciences.
[56] S. Akiyama,et al. A Novel Protease-docking Function of Integrin at Invadopodia* , 1999, The Journal of Biological Chemistry.
[57] J. Healey,et al. Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[58] A. Scott,et al. Antibody targeting in metastatic colon cancer: a phase I study of monoclonal antibody F19 against a cell-surface protein of reactive tumor stromal fibroblasts. , 1994, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[59] C. Morimoto,et al. Direct association of adenosine deaminase with a T cell activation antigen, CD26. , 1993, Science.
[60] A. Zallone,et al. Protein kinase C affects microfilaments, bone resorption, and [Ca2+]o sensing in cultured osteoclasts. , 1992, The American journal of physiology.
[61] Richard G. W. Anderson,et al. Caveolin, a protein component of caveolae membrane coats , 1992, Cell.
[62] L. Old,et al. Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[63] W. Krajewska,et al. Caveolins: structure and function in signal transduction. , 2004, Cellular & molecular biology letters.
[64] D. Gotley,et al. Endothelial cell serine proteases expressed during vascular morphogenesis and angiogenesis , 2003, Thrombosis and Haemostasis.
[65] Darren Kessner,et al. Bioinformatics Applications Note Proteowizard: Open Source Software for Rapid Proteomics Tools Development , 2022 .