Silencing SOCS3 could inhibit TNF-α induced apoptosis in 3T3-L1 and mouse preadipocytes

[1]  Chao Sun,et al.  p38 MAPK regulates calcium signal-mediated lipid accumulation through changing VDR expression in primary preadipocytes of mice , 2011, Molecular Biology Reports.

[2]  Shumin Liu,et al.  Calcium ameliorates obesity induced by high-fat diet and its potential correlation with p38 MAPK pathway , 2011, Molecular Biology Reports.

[3]  Chao Sun,et al.  DHA regulates lipogenesis and lipolysis genes in mice adipose and liver , 2011, Molecular Biology Reports.

[4]  K. Mishra,et al.  P22-25 Novel role of SOCS3 molecules in neural cells survival and differentiation , 2010, Clinical Neurophysiology.

[5]  M. Karin,et al.  Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer. , 2010, Cytokine & growth factor reviews.

[6]  Huang Pei-lin.  Effects of TNFα on proliferation and apoptosis of mouse adrenal cortex cell line Y1 , 2010 .

[7]  P. Schauer,et al.  Adipocyte Apoptosis, a Link between Obesity, Insulin Resistance, and Hepatic Steatosis* , 2009, The Journal of Biological Chemistry.

[8]  S. G. Rønn,et al.  Suppressor of cytokine signalling-3 inhibits tumor necrosis factor-alpha induced apoptosis and signalling in beta cells , 2009, Molecular and Cellular Endocrinology.

[9]  T. Imaizumi,et al.  Abstract 2947: Cardiac-Specific Deletion of SOCS3 Prevented Myocardial Apoptosis After Acute Myocardial Infarction Through Inhibiting Mitochondrial Damage , 2009 .

[10]  C. Bai,et al.  Restoration of SOCS3 suppresses human lung adenocarcinoma cell growth by downregulating activation of Erk1/2, Akt apart from STAT3 , 2009, Cell biology international.

[11]  N. Nikitakis,et al.  The oncogenic effects of constitutive Stat3 signaling in salivary gland cancer cells are mediated by survivin and modulated by the NSAID sulindac. , 2009, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[12]  Hua Yu,et al.  Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors. , 2009, Cancer cell.

[13]  Z. Tian,et al.  Growth inhibition of human hepatocellular carcinoma cells by blocking STAT3 activation with decoy-ODN. , 2008, Cancer letters.

[14]  R. Kramer,et al.  STAT3 signaling is induced by intercellular adhesion in squamous cell carcinoma cells. , 2008, Experimental cell research.

[15]  W. Qiang.  Effects of EGCG on regulating NF-κB/p65 induced by TNF-α and on inducing apoptosis , 2008 .

[16]  Q. Cheng.  Construction of the Oncolytic Adenovirus Carrying Human socs3 Gene and Investigation of Its Anti-tumor Activity in Vitro , 2008 .

[17]  M. Vieth,et al.  Methylation of SOCS-3 and SOCS-1 in the carcinogenesis of Barrett’s adenocarcinoma , 2007, Gut.

[18]  G. Gores,et al.  Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing. , 2007, Gastroenterology.

[19]  P. Cohen,et al.  Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex. , 2006, Molecular endocrinology.

[20]  F. Sommerer,et al.  SOCS-3 is frequently methylated in head and neck squamous cell carcinoma and its precursor lesions and causes growth inhibition , 2005, Oncogene.

[21]  D. Hilton,et al.  Inhibitors of Cytokine Signal Transduction* , 2004, Journal of Biological Chemistry.

[22]  Biao He,et al.  SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[23]  S. Fujita,et al.  Constitutive expression of SOCS3 confers resistance to IFN-alpha in chronic myelogenous leukemia cells. , 2002, Blood.

[24]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[25]  D. Hilton,et al.  SOCS Proteins: Negative Regulators of Cytokine Signaling , 2001, Stem cells.

[26]  T. Haruta,et al.  Mammalian Target of Rapamycin Pathway Regulates Insulin Signaling via Subcellular Redistribution of Insulin Receptor Substrate 1 and Integrates Nutritional Signals and Metabolic Signals of Insulin , 2001, Molecular and Cellular Biology.

[27]  Roy J Martin,et al.  TNFα Induces and Insulin Inhibits Caspase 3-Dependent Adipocyte Apoptosis , 2001 .

[28]  M. Wasik,et al.  STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma. , 2001, Blood.

[29]  J. Olefsky,et al.  A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1. , 2000, Molecular endocrinology.

[30]  S. O’Rahilly,et al.  Tumor Necrosis Factor-α Induces Apoptosis of Human Adipose Cells , 1997, Diabetes.

[31]  S. Akira,et al.  Structure and function of a new STAT-induced STAT inhibitor , 1997, Nature.

[32]  Warren S. Alexander,et al.  A family of cytokine-inducible inhibitors of signalling , 1997, Nature.

[33]  C. Niesler,et al.  Tumor necrosis factor-alpha induces apoptosis of human adipose cells. , 1997, Diabetes.

[34]  M. Benito,et al.  TNF-alpha induces apoptosis in rat fetal brown adipocytes in primary culture. , 1997, FEBS letters.

[35]  V. Fadok,et al.  Apoptosis and programmed cell death in immunity. , 1992, Annual review of immunology.