The Netrin family of guidance factors: emphasis on Netrin-1 signalling
暂无分享,去创建一个
[1] G. Gundersen. Microtubule Capture: IQGAP and CLIP-170 Expand the Repertoire , 2002, Current Biology.
[2] D. Bentley,et al. Accumulation of actin in subsets of pioneer growth cone filopodia in response to neural and epithelial guidance cues in situ , 1993, The Journal of cell biology.
[3] Timothy E. Kennedy,et al. Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord , 1994, Cell.
[4] M. Bastiani,et al. Guidance of neuronal growth cones: selective fasciculation in the grasshopper embryo. , 1983, Cold Spring Harbor symposia on quantitative biology.
[5] V. Gagliardini,et al. Semaphorin III Can Induce Death in Sensory Neurons , 1999, Molecular and Cellular Neuroscience.
[6] Z. Kaprielian,et al. The molecular basis of retinotectal topography , 1994, BioEssays : news and reviews in molecular, cellular and developmental biology.
[7] H. Cooper,et al. Netrin-3 protein is localized to the axons of motor, sensory, and sympathetic neurons , 2001, Mechanisms of Development.
[8] T. Pawson,et al. Multiple ephrins control cell organization in C. elegans using kinase-dependent and -independent functions of the VAB-1 Eph receptor. , 1999, Molecular cell.
[9] P. Forscher,et al. Cytoskeletal remodeling during growth cone-target interactions , 1993, The Journal of cell biology.
[10] Veeranna,et al. Phosphorylation of MEK1 by cdk5/p35 Down-regulates the Mitogen-activated Protein Kinase Pathway* , 2002, The Journal of Biological Chemistry.
[11] Y. Rao,et al. Molecular control of neuronal migration. , 2002, BioEssays : news and reviews in molecular, cellular and developmental biology.
[12] I Biaggioni,et al. Adenosine A2B receptors. , 1997, Pharmacological reviews.
[13] M. Tessier-Lavigne,et al. Function of an axonal chemoattractant modulated by metalloprotease activity. , 2000, Science.
[14] D. Brown,et al. The tyrosine kinase connection: how GPI-anchored proteins activate T cells. , 1993, Current opinion in immunology.
[15] R. Yuste,et al. Aberrant development of hippocampal circuits and altered neural activity in netrin 1-deficient mice. , 2000, Development.
[16] A. B. Huber,et al. Signaling at the growth cone: ligand-receptor complexes and the control of axon growth and guidance. , 2003, Annual review of neuroscience.
[17] John G Flanagan,et al. Topographically Specific Effects of ELF-1 on Retinal Axon Guidance In Vitro and Retinal Axon Mapping In Vivo , 1996, Cell.
[18] Lindsay Hinck,et al. Netrin-1/neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis. , 2003, Developmental cell.
[19] C. Métin,et al. A role for netrin-1 in the guidance of cortical efferents. , 1997, Development.
[20] G. Ming,et al. A CaMKII/Calcineurin Switch Controls the Direction of Ca2+-Dependent Growth Cone Guidance , 2004, Neuron.
[21] F. Bonhoeffer,et al. In vitro experiments on axon guidance demonstrating an anterior‐posterior gradient on the tectum. , 1982, The EMBO journal.
[22] A. Chédotal,et al. Directional Guidance of Oligodendroglial Migration by Class 3 Semaphorins and Netrin-1 , 2002, The Journal of Neuroscience.
[23] M. Kirschner,et al. Microtubule behavior in the growth cones of living neurons during axon elongation , 1991, The Journal of cell biology.
[24] J. Culotti,et al. UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans , 1992, Cell.
[25] J. Tschopp,et al. The death domain motif found in Fas (Apo‐1) and TNF receptor is present in proteins involved in apoptosis and axonal guidance , 1995, FEBS letters.
[26] J. Culotti,et al. UNC-40, a C. elegans Homolog of DCC (Deleted in Colorectal Cancer), Is Required in Motile Cells Responding to UNC-6 Netrin Cues , 1996, Cell.
[27] D. Moscatelli,et al. The FGF family of growth factors and oncogenes. , 1992, Advances in cancer research.
[28] D. V. Vactor. Adhesion and signaling in axonal fasciculation , 1998, Current Opinion in Neurobiology.
[29] Michael Piper,et al. Movement through slits: Cellular migration via the Slit family , 2003, BioEssays : news and reviews in molecular, cellular and developmental biology.
[30] A. Wilks,et al. The expression patterns of guidance receptors, DCC and Neogenin, are spatially and temporally distinct throughout mouse embryogenesis. , 1997, Developmental biology.
[31] C. Goodman,et al. Genetic Analysis of the Mechanisms Controlling Target Selection: Complementary and Combinatorial Functions of Netrins, Semaphorins, and IgCAMs , 1998, Cell.
[32] Michael S. Deiner,et al. Altered Midline Axon Pathways and Ectopic Neurons in the Developing Hypothalamus of Netrin-1- and DCC-Deficient Mice , 1999, The Journal of Neuroscience.
[33] B. Hogan,et al. Novel Role for Netrins in Regulating Epithelial Behavior during Lung Branching Morphogenesis , 2004, Current Biology.
[34] S. R. Y. Cajal. La rétine des vertébrés , 1892 .
[35] E. Hedgecock,et al. Neuroglia and Pioneer Neurons Express UNC-6 to Provide Global and Local Netrin Cues for Guiding Migrations in C. elegans , 1996, Neuron.
[36] I. Fischer,et al. MAP1B expression and microtubule stability in growing and regenerating axons , 2000, Microscopy research and technique.
[37] J. Hsieh,et al. Induction of apoptosis and G2/M cell cycle arrest by DCC , 1999, Oncogene.
[38] J. Bolz,et al. Semaphorin 3A–Vascular Endothelial Growth Factor-165 Balance Mediates Migration and Apoptosis of Neural Progenitor Cells by the Recruitment of Shared Receptor , 2001, The Journal of Neuroscience.
[39] J. Culotti,et al. UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans , 1992, Neuron.
[40] H. Keshishian,et al. Neuronal pathfinding and recognition: roles of cell adhesion molecules. , 1996, Developmental biology.
[41] Mu-ming Poo,et al. Turning of Retinal Growth Cones in a Netrin-1 Gradient Mediated by the Netrin Receptor DCC , 1997, Neuron.
[42] M. Condic,et al. Characterization of Netrin-1, Neogenin and cUNC-5H3 expression during chick dorsal root ganglia development. , 2003, Gene expression patterns : GEP.
[43] J. Sanes,et al. Identification and expression of mouse netrin-4 , 2000, Mechanisms of Development.
[44] M. Poo,et al. Binding of DCC by Netrin-1 to Mediate Axon Guidance Independent of Adenosine A2B Receptor Activation , 2001, Science.
[45] C. Goodman,et al. Slit Is the Midline Repellent for the Robo Receptor in Drosophila , 1999, Cell.
[46] C. Goodman,et al. Genes that control neuromuscular specificity in Drosophila , 1993, Cell.
[47] A. Sweatt,et al. Microtubule-associated protein 1 subunit expression in primary cultures of rat brain , 2000, Brain Research Bulletin.
[48] W. Dreyer,et al. Neogenin, an avian cell surface protein expressed during terminal neuronal differentiation, is closely related to the human tumor suppressor molecule deleted in colorectal cancer , 1994, The Journal of cell biology.
[49] D. Gilbert,et al. Netrin-3, a Mouse Homolog of Human NTN2L, Is Highly Expressed in Sensory Ganglia and Shows Differential Binding to Netrin Receptors , 1999, The Journal of Neuroscience.
[50] L. Astic,et al. Expression of netrin-1 and netrin-1 receptor, DCC, in the rat olfactory nerve pathway during development and axonal regeneration , 2002, Neuroscience.
[51] P. Devreotes,et al. Chemotaxis in eukaryotic cells: a focus on leukocytes and Dictyostelium. , 1988, Annual review of cell biology.
[52] C. Holt,et al. Navigational errors made by growth cones without filopodia in the embryonic xenopus brain , 1993, Neuron.
[53] P. Maness,et al. A MAP Kinase-Signaling Pathway Mediates Neurite Outgrowth on L1 and Requires Src-Dependent Endocytosis , 2000, The Journal of Neuroscience.
[54] Hao Wang,et al. Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System , 1996, Cell.
[55] Kathleen R. Cho,et al. The DCC gene product in cellular differentiation and colorectal tumorigenesis. , 1994, Genes & development.
[56] A. Schuldt. Developmental biology: Guidance molecule goes global , 2003, Nature.
[57] J. Rhim,et al. Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway , 2001, Nature Cell Biology.
[58] M. Hatten. Central nervous system neuronal migration. , 1999, Annual review of neuroscience.
[59] D. V. Vactor,et al. From the growth cone surface to the cytoskeleton: one journey, many paths. , 2000, Journal of neurobiology.
[60] R. Stancou,et al. Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. , 1996, The EMBO journal.
[61] A. Chédotal,et al. Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor , 2000, Nature.
[62] T. Kennedy,et al. Widespread Expression of Netrin-1 by Neurons and Oligodendrocytes in the Adult Mammalian Spinal Cord , 2001, The Journal of Neuroscience.
[63] A. Kolodkin,et al. Functions of netrins and semaphorins in axon guidance , 1996, Current Opinion in Neurobiology.
[64] T. Kennedy,et al. The Adaptor Protein Nck-1 Couples the Netrin-1 Receptor DCC (Deleted in Colorectal Cancer) to the Activation of the Small GTPase Rac1 through an Atypical Mechanism* , 2002, The Journal of Biological Chemistry.
[65] J. Sanes,et al. Lamina-specific cues guide outgrowth and arborization of retinal axons in the optic tectum. , 1995, Development.
[66] T. Pawson,et al. Netrin Stimulates Tyrosine Phosphorylation of the UNC-5 Family of Netrin Receptors and Induces Shp2 Binding to the RCM Cytodomain* , 2001, The Journal of Biological Chemistry.
[67] L. Krushel,et al. Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily , 2000, Developmental dynamics : an official publication of the American Association of Anatomists.
[68] S. Shimeld. An amphioxus netrin gene is expressed in midline structures during embryonic and larval development , 2000, Development Genes and Evolution.
[69] A. Hall,et al. Rho GTPases and the actin cytoskeleton. , 1998, Science.
[70] K. Klinger,et al. The NTN2L gene encoding a novel human netrin maps to the autosomal dominant polycystic kidney disease region on chromosome 16p13.3. , 1997, Genomics.
[71] C. Holt,et al. Apoptotic Pathway and MAPKs Differentially Regulate Chemotropic Responses of Retinal Growth Cones , 2003, Neuron.
[72] J. Juang,et al. enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties. , 1995, Genes & development.
[73] F. Llambi,et al. Netrin‐1 acts as a survival factor via its receptors UNC5H and DCC , 2001, The EMBO journal.
[74] M. Tessier-Lavigne,et al. Hierarchical Organization of Guidance Receptors: Silencing of Netrin Attraction by Slit Through a Robo/DCC Receptor Complex , 2001, Science.
[75] S. Cohen-Cory. The double life of netrin , 2002, Nature Neuroscience.
[76] Li-Huei Tsai,et al. A decade of CDK5 , 2001, Nature Reviews Molecular Cell Biology.
[77] M. Tessier-Lavigne,et al. Coordinated functions of Netrin-1 and Class 3 secreted Semaphorins in the guidance of reciprocal septohippocampal connections , 2004, Molecular and Cellular Neuroscience.
[78] A. Horwitz,et al. Deleted in Colorectal Carcinoma and Differentially Expressed Integrins Mediate the Directional Migration of Neural Precursors in the Rostral Migratory Stream , 2002, The Journal of Neuroscience.
[79] M. Tessier-Lavigne,et al. Recognition of the Neural Chemoattractant Netrin-1 by Integrins α6β4 and α3β1 Regulates Epithelial Cell Adhesion and Migration , 2003 .
[80] T. Kennedy. Cellular mechanisms of netrin function: long-range and short-range actions. , 2000, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[81] Jennifer L. Doyle,et al. Genetic Analysis of Netrin Genes in Drosophila: Netrins Guide CNS Commissural Axons and Peripheral Motor Axons , 1996, Neuron.
[82] J. Ávila,et al. MAP1B Is Required for Netrin 1 Signaling in Neuronal Migration and Axonal Guidance , 2004, Current Biology.
[83] C. Bate. Pioneer neurones in an insect embryo , 1976, Nature.
[84] P. Aspenström. Effectors for the Rho GTPases. , 1999, Current opinion in cell biology.
[85] M. Tessier-Lavigne,et al. The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons , 1995, Cell.
[86] Y. Jan,et al. frazzled Encodes a Drosophila Member of the DCC Immunoglobulin Subfamily and Is Required for CNS and Motor Axon Guidance , 1996, Cell.
[87] M. Bate,et al. Presynaptic Development at the Drosophila Neuromuscular Junction: Assembly and Localization of Presynaptic Active Zones , 1996, Neuron.
[88] C. Waterman-Storer,et al. Cell motility: can Rho GTPases and microtubules point the way? , 2001, Journal of cell science.
[89] Yukitaka Ushio,et al. A Role of Netrin-1 in the Formation of the Subcortical Structure Striatum: Repulsive Action on the Migration of Late-Born Striatal Neurons , 2001, The Journal of Neuroscience.
[90] Mu-ming Poo,et al. A Ligand-Gated Association between Cytoplasmic Domains of UNC5 and DCC Family Receptors Converts Netrin-Induced Growth Cone Attraction to Repulsion , 1999, Cell.
[91] C. Holt,et al. FGF signaling and target recognition in the developing xenopus visual system , 1995, Neuron.
[92] L. Luo. RHO GTPASES in neuronal morphogenesis , 2000, Nature Reviews Neuroscience.
[93] M. Hanson,et al. Hepatocyte Growth Factor/Scatter Factor Is an Axonal Chemoattractant and a Neurotrophic Factor for Spinal Motor Neurons , 1996, Neuron.
[94] James Q. Zheng,et al. Growth Cone Turning Induced by Direct Local Modification of Microtubule Dynamics , 2002, The Journal of Neuroscience.
[95] Marc Tessier-Lavigne,et al. Target attraction: Are developing axons guided by chemotropism? , 1991, Trends in Neurosciences.
[96] S. Diriong,et al. The two guanine nucleotide exchange factor domains of Trio link the Rac1 and the RhoA pathways in vivo , 1998, Oncogene.
[97] B. Mueller,et al. Growth cone guidance: first steps towards a deeper understanding. , 1999, Annual review of neuroscience.
[98] A. Püschel. Divergent properties of mouse netrins , 1999, Mechanisms of Development.
[99] K. Komatsuzaki,et al. Modulation of Giα2 signaling by the axonal guidance molecule UNC5H2 , 2002 .
[100] M. Kirschner,et al. The role of microtubule dynamics in growth cone motility and axonal growth , 1995, The Journal of cell biology.
[101] J. Dodd,et al. Axon guidance: A compelling case for repelling growth cones , 1995, Cell.
[102] J. Verhaagen,et al. Ectopic adenoviral vector-directed expression of Sema3A in organotypic spinal cord explants inhibits growth of primary sensory afferents. , 2000, Developmental biology.
[103] J. Culotti,et al. DCC and netrins. , 1998, Current opinion in cell biology.
[104] Mu-ming Poo,et al. Adaptation in the chemotactic guidance of nerve growth cones , 2002, Nature.
[105] N. Tamamaki,et al. Guidance of glial precursor cell migration by secreted cues in the developing optic nerve. , 2001, Development.
[106] James D. Lauderdale,et al. Axon Tracts Correlate withNetrin-1aExpression in the Zebrafish Embryo , 1997, Molecular and Cellular Neuroscience.
[107] M. Masu,et al. Deleted in Colorectal Cancer (DCC) Encodes a Netrin Receptor , 1996, Cell.
[108] T. Kennedy,et al. Oligodendrocyte Precursors on the Move: Mechanisms Directing Migration , 2004, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
[109] P. Forscher,et al. Cytoskeletal reorganization underlying growth cone motility , 1994, Current Opinion in Neurobiology.
[110] K. Aktories,et al. Rac1 and Cdc42 but Not RhoA or Rho Kinase Activities Are Required for Neurite Outgrowth Induced by the Netrin-1 Receptor DCC (Deleted in Colorectal Cancer) in N1E-115 Neuroblastoma Cells* , 2002, The Journal of Biological Chemistry.
[111] R. Hoffmann,et al. Glycosaminoglycan-binding properties and secondary structure of the C-terminus of netrin-1. , 2000, Biochemical and biophysical research communications.
[112] B. Emery,et al. Localization of the netrin guidance receptor, DCC, in the developing peripheral and enteric nervous systems , 2001, Mechanisms of Development.
[113] E. Fearon,et al. DCC: linking tumour suppressor genes and altered cell surface interactions in cancer? , 1995, European journal of cancer.
[114] J. Wehland,et al. Mena, a Relative of VASP and Drosophila Enabled, Is Implicated in the Control of Microfilament Dynamics , 1996, Cell.
[115] P. Forscher,et al. Substrate-cytoskeletal coupling as a mechanism for the regulation of growth cone motility and guidance. , 2000, Journal of neurobiology.
[116] K. Kullander,et al. Mechanisms and functions of eph and ephrin signalling , 2002, Nature Reviews Molecular Cell Biology.
[117] B. Pedrotti,et al. Microtubule associated protein 1B (MAP1B) promotes efficient tubulin polymerisation in vitro , 1995, FEBS letters.
[118] I. Rooman,et al. Netrin-1 expression in fetal and regenerating rat pancreas and its effect on the migration of human pancreatic duct and porcine islet precursor cells , 2003, Diabetologia.
[119] M. Tessier-Lavigne,et al. The role of the floor plate in axon guidance. , 1995, Annual review of neuroscience.
[120] M. Salminen,et al. Developmentally regulated expression of Netrin‐1 and ‐3 in the embryonic mouse molar tooth germ , 2003, Developmental dynamics : an official publication of the American Association of Anatomists.
[121] S. Tobet,et al. Deleted in Colorectal Cancer (DCC) Regulates the Migration of Luteinizing Hormone-Releasing Hormone Neurons to the Basal Forebrain , 2001, The Journal of Neuroscience.
[122] O. Cussenot,et al. Quantification of expression of netrins, slits and their receptors in human prostate tumors , 2003, International journal of cancer.
[123] F. Bonhoeffer,et al. Recognition of cell types by axonal growth cones in vitro , 1980, Nature.
[124] S. Zipursky,et al. Glial Cells Mediate Target Layer Selection of Retinal Axons in the Developing Visual System of Drosophila , 2001, Neuron.
[125] Li I. Zhang,et al. Electrical activity and development of neural circuits , 2001, Nature Neuroscience.
[126] Anne J. Ridley,et al. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors , 1992, Cell.
[127] Cornelia I. Bargmann,et al. Inhibition of Netrin-Mediated Axon Attraction by a Receptor Protein Tyrosine Phosphatase , 2004, Science.
[128] G. Pollerberg,et al. The Microtubule-Associated Protein MAP1B Is Involved in Local Stabilization of Turning Growth Cones , 2000, Molecular and Cellular Neuroscience.
[129] C. Shatz,et al. Developmental mechanisms that generate precise patterns of neuronal connectivity , 1993, Cell.
[130] I. Fischer,et al. Microtubule-associated protein 1b (MAP1b) is concentrated in the distal region of growing axons , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[131] P. Mehlen,et al. The dependence receptors DCC and UNC5H as a link between neuronal guidance and survival , 2003, Biology of the cell.
[132] T. Jessell,et al. The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6 , 1994, Cell.
[133] T. Kennedy,et al. Netrin-1 Is a Chemorepellent for Oligodendrocyte Precursor Cells in the Embryonic Spinal Cord , 2003, The Journal of Neuroscience.
[134] R. Goold,et al. Inhibition of GSK-3beta leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium. , 1998, Journal of cell science.
[135] Alain Chédotal,et al. Role of Slit proteins in the vertebrate brain , 2002, Journal of Physiology-Paris.
[136] Anne J. Ridley,et al. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling , 1992, Cell.
[137] Michael S. Deiner,et al. Netrin-1 and DCC Mediate Axon Guidance Locally at the Optic Disc: Loss of Function Leads to Optic Nerve Hypoplasia , 1997, Neuron.
[138] Yusuke Nakamura,et al. p53RDL1 regulates p53-dependent apoptosis , 2003, Nature Cell Biology.
[139] Kristin L. Whitford,et al. Plexin Signaling via Off-Track and Rho Family GTPases , 2001, Neuron.
[140] M. Tessier-Lavigne,et al. MAX-1, a Novel PH/MyTH4/FERM Domain Cytoplasmic Protein Implicated in Netrin-Mediated Axon Repulsion , 2002, Neuron.
[141] A. Wilks,et al. Cloning of the mouse homologue of the deleted in colorectal cancer gene (mDCC) and its expression in the developing mouse embryo. , 1995, Oncogene.
[142] H. Herrmann,et al. Microheterogeneity of microtubule-associated proteins, MAP-1 and MAP-2, and differential phosphorylation of individual subcomponents. , 1985, The Journal of biological chemistry.
[143] H. Baba,et al. Netrin‐1 is crucial for the establishment of the dorsal column‐medial lemniscal system , 2004, Journal of neurochemistry.
[144] F. Castro. Chemotropic Molecules: Guides for Axonal Pathfinding and Cell Migration During CNS Development , 2003 .
[145] A. Gurney,et al. The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons , 2003, Nature Neuroscience.
[146] L. Lim,et al. The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts , 1995, Molecular and cellular biology.
[147] M. Masu,et al. Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors , 1997, Nature.
[148] C. Sotelo,et al. Netrin 1 acts as an attractive or as a repulsive cue for distinct migrating neurons during the development of the cerebellar system. , 2000, Development.
[149] I. Black,et al. Regulation of topographic projection in the brain: Elf-1 in the hippocamposeptal system. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[150] D. Hall,et al. The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans , 1990, Neuron.
[151] S. Skaper,et al. Cell signalling cascades regulating neuronal growth-promoting and inhibitory cues , 2001, Progress in Neurobiology.
[152] C. Nobes,et al. Rho, rac and cdc42 GTPases: regulators of actin structures, cell adhesion and motility. , 1995, Biochemical Society transactions.
[153] C. Cohan,et al. Focal loss of actin bundles causes microtubule redistribution and growth cone turning , 2002, The Journal of cell biology.
[154] J Schultz,et al. SMART, a simple modular architecture research tool: identification of signaling domains. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[155] Jonathan A Raper,et al. Semaphorins and their receptors in vertebrates and invertebrates , 2000, Current Opinion in Neurobiology.
[156] R. Fields,et al. Neural cell adhesion molecules in activity-dependent development and synaptic plasticity , 1996, Trends in Neurosciences.
[157] J. Ávila,et al. Evidence for the role of MAP1B in axon formation. , 2001, Molecular biology of the cell.
[158] Russell L Finley,et al. Mediation of the DCC Apoptotic Signal by DIP13α* , 2002, The Journal of Biological Chemistry.
[159] C. Marshall,et al. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells , 1994, Cell.
[160] D. Colman,et al. A Model for Central Synaptic Junctional Complex Formation Based on the Differential Adhesive Specificities of the Cadherins , 1996, Neuron.
[161] G. Borisy,et al. Specific association of an M-phase kinase with isolated mitotic spindles and identification of two of its substrates as MAP4 and MAP1B. , 1991, Cell regulation.
[162] R. Kalb,et al. Molecular basis of semaphorin-mediated axon guidance. , 2000, Journal of neurobiology.
[163] A. Pini,et al. Chemorepulsion of developing motor axons by the floor plate , 1995, Neuron.
[164] B. Dickson,et al. Axon Guidance: Growth Cones Make an Unexpected Turn , 2002, Current Biology.
[165] M. Barbacid. Neurotrophic Factors and Their Receptors , 1995, Bio/Technology.
[166] G. Tear. Neuronal guidance. A genetic perspective. , 1999, Trends in genetics : TIG.
[167] H. Cooper,et al. Mouse Neogenin, a DCC-like molecule, has four splice variants and is expressed widely in the adult mouse and during embryogenesis , 1997, Oncogene.
[168] C. Sotelo,et al. Floor Plate and Netrin-1 Are Involved in the Migration and Survival of Inferior Olivary Neurons , 1999, The Journal of Neuroscience.
[169] D. Van Vactor,et al. Axon guidance: the cytoplasmic tail. , 2002, Current opinion in cell biology.
[170] P. Comoglio,et al. Signalling by semaphorin receptors: cell guidance and beyond. , 2000, Trends in cell biology.
[171] S. Kuroda,et al. Rac1 and Cdc42 Capture Microtubules through IQGAP1 and CLIP-170 , 2002, Cell.
[172] Robert H Miller,et al. Glial cell migration directed by axon guidance cues , 2002, Trends in Neurosciences.
[173] J. Meyerhardt,et al. Netrin-1: interaction with deleted in colorectal cancer (DCC) and alterations in brain tumors and neuroblastomas. , 1999, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[174] A. Hall,et al. Rac/Cdc42 and p65PAK Regulate the Microtubule-destabilizing Protein Stathmin through Phosphorylation at Serine 16* , 2001, The Journal of Biological Chemistry.
[175] C. Chuong,et al. cDCC (chicken homologue to a gene deleted in colorectal carcinoma) is an epithelial adhesion molecule expressed in the basal cells and involved in epithelial-mesenchymal interaction. , 1994, Developmental biology.
[176] M. Feller,et al. Spontaneous Correlated Activity in Developing Neural Circuits , 1999, Neuron.
[177] L. Landmesser,et al. Axon guidance at choice points , 1998, Current Opinion in Neurobiology.
[178] C. Goodman,et al. Biochemical Purification of a Mammalian Slit Protein as a Positive Regulator of Sensory Axon Elongation and Branching , 1999, Cell.
[179] M. Poo,et al. The cell biology of neuronal navigation , 2001, Nature Cell Biology.
[180] D. V. Vactor,et al. The Microtubule Plus End Tracking Protein Orbit/MAST/CLASP Acts Downstream of the Tyrosine Kinase Abl in Mediating Axon Guidance , 2004, Neuron.
[181] J. Sanes,et al. Laminets: Laminin- and Netrin-Related Genes Expressed in Distinct Neuronal Subsets , 2002, Molecular and Cellular Neuroscience.
[182] T. Kennedy,et al. Developmental shift in expression of netrin receptors in the rat spinal cord: Predominance of UNC‐5 homologues in adulthood , 2004, Journal of neuroscience research.
[183] V. Lemmon,et al. Dynamic regulation of cell adhesion molecules during axon outgrowth. , 2000, Journal of neurobiology.
[184] Seizo Yamamoto,et al. Expression of mRNA for axon guidance molecules, such as semaphorin-III, netrins and neurotrophins, in human osteoblasts and osteoclasts , 2000, Brain Research.
[185] Jacqueline H. Finger,et al. The Netrin 1 Receptors Unc5h3 and Dcc Are Necessary at Multiple Choice Points for the Guidance of Corticospinal Tract Axons , 2002, The Journal of Neuroscience.
[186] E. Frank,et al. SEMA3A regulates developing sensory projections in the chicken spinal cord. , 2000, Journal of neurobiology.
[187] Ken Watanabe,et al. UNC5H1 Induces Apoptosis via Its Juxtamembrane Region through an Interaction with NRAGE* , 2003, The Journal of Biological Chemistry.
[188] Cori Bargmann,et al. Dynamic regulation of axon guidance , 2001, Nature Neuroscience.
[189] B. Dickson,et al. Short- and Long-Range Repulsion by the Drosophila Unc5 Netrin Receptor , 2001, Neuron.
[190] Mu-ming Poo,et al. Signal transduction underlying growth cone guidance by diffusible factors , 1999, Current Opinion in Neurobiology.
[191] Cori Bargmann,et al. The Netrin Receptor UNC-40/DCC Stimulates Axon Attraction and Outgrowth through Enabled and, in Parallel, Rac and UNC-115/AbLIM , 2003, Neuron.
[192] Mu-ming Poo,et al. Calcium signalling in the guidance of nerve growth by netrin-1 , 2000, Nature.
[193] H. Katoh,et al. Rho family GTPases as key regulators for neuronal network formation. , 2002, Journal of biochemistry.
[194] P. Forscher,et al. Growth cone advance is inversely proportional to retrograde F-actin flow , 1995, Neuron.
[195] Kimberly M. Valentino,et al. Expression of the Netrin‐1 receptor, deleted in colorectal cancer (DCC), is largely confined to projecting neurons in the developing forebrain , 2000, The Journal of comparative neurology.
[196] A. Kolodkin,et al. Silencing the Siren Guidance Cue Hierarchies at the CNS Midline , 2001, Cell.
[197] M. Tessier-Lavigne,et al. Netrin 1 mediates spinal cord oligodendrocyte precursor dispersal , 2003, Development.
[198] C. Shatz,et al. Netrin-1 Promotes Thalamic Axon Growth and Is Required for Proper Development of the Thalamocortical Projection , 2000, The Journal of Neuroscience.
[199] S. Dedhar,et al. NGF-Induced Axon Growth Is Mediated by Localized Inactivation of GSK-3β and Functions of the Microtubule Plus End Binding Protein APC , 2004, Neuron.
[200] C. Sotelo,et al. Slit antagonizes netrin-1 attractive effects during the migration of inferior olivary neurons. , 2002, Developmental biology.
[201] L. Tsai,et al. Cdk5 on the brain. , 2001, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[202] David G. Wilkinson,et al. Multiple roles of eph receptors and ephrins in neural development , 2001, Nature Reviews Neuroscience.
[203] T. Kennedy,et al. The Netrin-1 Receptor DCC Promotes Filopodia Formation and Cell Spreading by Activating Cdc42 and Rac1 , 2002, Molecular and Cellular Neuroscience.
[204] D. Bredesen,et al. Netrin-1 controls colorectal tumorigenesis by regulating apoptosis , 2004, Nature.
[205] M. Tessier-Lavigne,et al. Slit proteins: key regulators of axon guidance, axonal branching, and cell migration , 2000, Current Opinion in Neurobiology.
[206] L. Richards,et al. Directed Growth of Early Cortical Axons Is Influenced by a Chemoattractant Released from an Intermediate Target , 1997, The Journal of Neuroscience.
[207] T. Pawson,et al. UNC-5 function requires phosphorylation of cytoplasmic tyrosine 482, but its UNC-40-independent functions also require a region between the ZU-5 and death domains. , 2002, Developmental biology.
[208] S. Strittmatter,et al. Semaphorin-mediated axonal guidance via Rho-related G proteins. , 2001, Current opinion in cell biology.
[209] M. Frotscher,et al. A role for Cajal–Retzius cells and reelin in the development of hippocampal connections , 1997, Nature.
[210] E. Nishida,et al. ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1 , 2001, Nature Cell Biology.
[211] J. Flanagan. Life on the road , 1999, Nature.
[212] M. Schachner,et al. Analysis of the L1-Deficient Mouse Phenotype Reveals Cross-Talk between Sema3A and L1 Signaling Pathways in Axonal Guidance , 2000, Neuron.
[213] Giovanni Romeo,et al. The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[214] M. Barbacid,et al. Ephrins and their Eph receptors: multitalented directors of embryonic development , 1999, The EMBO journal.
[215] P. Fort,et al. Distinct roles of Rac1/Cdc42 and Rho/Rock for axon outgrowth and nucleokinesis of precerebellar neurons toward netrin 1 , 2004, Development.
[216] B. Pedrotti,et al. Dephosphorylated but not phosphorylated microtubule associated protein MAP1B binds to microfilaments , 1996, FEBS letters.
[217] D. Engelkamp. Cloning of three mouse Unc5 genes and their expression patterns at mid-gestation , 2002, Mechanisms of Development.
[218] Roger Keynes,et al. Axon guidance to and from choice points , 1998, Current Opinion in Neurobiology.
[219] Cori Bargmann,et al. Shared receptors in axon guidance: SAX-3/Robo signals via UNC-34/Enabled and a Netrin-independent UNC-40/DCC function , 2002, Nature Neuroscience.
[220] C. Goodman,et al. The Molecular Biology of Axon Guidance , 1996, Science.
[221] C. Holt,et al. Target selection: invasion, mapping and cell choice , 1998, Current Opinion in Neurobiology.
[222] P. Caroni. Driving the Growth Cone , 1998, Science.
[223] L. Hinck,et al. Surface Expression of the Netrin Receptor UNC5H1 Is Regulated through a Protein Kinase C-Interacting Protein/Protein Kinase-Dependent Mechanism , 2003, The Journal of Neuroscience.
[224] S. Itohara,et al. Netrin-G1: a Novel Glycosyl Phosphatidylinositol-Linked Mammalian Netrin That Is Functionally Divergent from Classical Netrins , 2000, The Journal of Neuroscience.
[225] E. Nishida,et al. Induction of neurite outgrowth by MAP kinase in PC12 cells. , 1995, Oncogene.
[226] S. Guthrie. Axon guidance: Netrin receptors are revealed , 1997, Current Biology.
[227] M. Schachner,et al. Microtubule reorganization is obligatory for growth cone turning. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[228] S. Zipursky,et al. Neuronal target recognition , 1995, Cell.
[229] F. Walsh,et al. Neural cell adhesion molecules of the immunoglobulin superfamily: role in axon growth and guidance. , 1997, Annual review of cell and developmental biology.
[230] Philippe Soriano,et al. Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion. , 1999, Genes & development.
[231] S. Itohara,et al. Complementary expression and neurite outgrowth activity of netrin-G subfamily members , 2002, Mechanisms of Development.
[232] N. Yamamoto,et al. Wiring of the brain by a range of guidance cues , 2002, Progress in Neurobiology.
[233] R. Weinberg,et al. Phenotype of mice lacking functional Deleted in colorectal cancer (Dec) gene , 1997, Nature.
[234] C. Holt,et al. Chemotropic Responses of Retinal Growth Cones Mediated by Rapid Local Protein Synthesis and Degradation , 2001, Neuron.
[235] L. Richards,et al. The spatial and temporal expression patterns of netrin receptors, DCC and neogenin, in the developing mouse retina. , 2000, Experimental eye research.
[236] J. Minna,et al. SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers. , 2002, Cancer research.
[237] Marc Tessier-Lavigne,et al. Conservation and divergence of axon guidance mechanisms , 1999, Current Opinion in Neurobiology.
[238] A. W. Schaefer,et al. Filopodia and actin arcs guide the assembly and transport of two populations of microtubules with unique dynamic parameters in neuronal growth cones , 2002, The Journal of cell biology.
[239] C. Goodman,et al. Slit Proteins Bind Robo Receptors and Have an Evolutionarily Conserved Role in Repulsive Axon Guidance , 1999, Cell.
[240] Stefan A. Przyborski,et al. The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein , 1997, Nature.
[241] D. Leahy,et al. Netrin Binds Discrete Subdomains of DCC and UNC5 and Mediates Interactions between DCC and Heparin* , 2003, Journal of Biological Chemistry.
[242] M. Tessier-Lavigne,et al. Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation , 2002, Nature.
[243] F. J. Livesey. Netrins and netrin receptorsRID="†"ID="†" Review , 1999, Cellular and Molecular Life Sciences CMLS.
[244] Kathleen R. Cho,et al. Identification of a chromosome 18q gene that is altered in colorectal cancers. , 1990, Science.
[245] V. Berezin,et al. Neural Cell Adhesion Molecule-Stimulated Neurite Outgrowth Depends on Activation of Protein Kinase C and the Ras–Mitogen-Activated Protein Kinase Pathway , 2000, The Journal of Neuroscience.
[246] C. E. Holt,et al. Age-related changes underlie switch in netrin-1 responsiveness as growth cones advance along visual pathway , 2002, Nature Neuroscience.
[247] M. Tessier-Lavigne,et al. En passant neurotrophic action of an intermediate axonal target in the developing mammalian CNS , 1999, Nature.
[248] M. Poo,et al. Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning , 2003, Nature.
[249] Hiroshi Takahashi,et al. Axonal Growth from the Habenular Nucleus along the Neuromere Boundary Region of the Diencephalon Is Regulated by Semaphorin 3F and Netrin-1 , 2000, Molecular and Cellular Neuroscience.
[250] F. J. Livesey,et al. Netrin and Netrin Receptor Expression in the Embryonic Mammalian Nervous System Suggests Roles in Retinal, Striatal, Nigral, and Cerebellar Development , 1997, Molecular and Cellular Neuroscience.
[251] A. Barzilai,et al. Semaphorins as Mediators of Neuronal Apoptosis , 1999, Journal of neurochemistry.
[252] A. McMahon,et al. The Morphogen Sonic Hedgehog Is an Axonal Chemoattractant that Collaborates with Netrin-1 in Midline Axon Guidance , 2003, Cell.
[253] J. Challacombe,et al. Dynamic Microtubule Ends Are Required for Growth Cone Turning to Avoid an Inhibitory Guidance Cue , 1997, The Journal of Neuroscience.
[254] F. Murakami,et al. Guidance of Circumferentially Growing Axons by Netrin-Dependent and -Independent Floor Plate Chemotropism in the Vertebrate Brain , 1996, Neuron.
[255] N. Assa‐Munt,et al. p75NTR and the concept of cellular dependence: seeing how the other half die , 1998, Cell Death and Differentiation.
[256] Marc Tessier-Lavigne,et al. Extension of Long Leading Processes and Neuronal Migration in the Mammalian Brain Directed by the Chemoattractant Netrin-1 , 1999, Neuron.
[257] H. Pearson. Drug discovery: In the eye of the beholder , 2003, Nature.
[258] M. Kirschner,et al. The role of microtubules in growth cone turning at substrate boundaries , 1995, The Journal of cell biology.
[259] M. Seeger,et al. Guidance Cues at the Drosophila CNS Midline: Identification and Characterization of Two Drosophila Netrin/UNC-6 Homologs , 1996, Neuron.
[260] R. Burgeson,et al. A Novel Member of the Netrin Family, β-Netrin, Shares Homology with the β Chain of Laminin , 2000, The Journal of cell biology.
[261] Mu-ming Poo,et al. cAMP-Dependent Growth Cone Guidance by Netrin-1 , 1997, Neuron.
[262] Moving On , 2001, Science.
[263] Philippe P Roux,et al. Protein Kinase A Activation Promotes Plasma Membrane Insertion of DCC from an Intracellular Pool: A Novel Mechanism Regulating Commissural Axon Extension , 2004, The Journal of Neuroscience.
[264] P. Gruss,et al. Netrin 1 is required for semicircular canal formation in the mouse inner ear. , 2000, Development.
[265] R. Sperry. CHEMOAFFINITY IN THE ORDERLY GROWTH OF NERVE FIBER PATTERNS AND CONNECTIONS. , 1963, Proceedings of the National Academy of Sciences of the United States of America.
[266] M. Poo,et al. Phospholipase C-γ and Phosphoinositide 3-Kinase Mediate Cytoplasmic Signaling in Nerve Growth Cone Guidance , 1999, Neuron.
[267] Shahrooz Rabizadeh,et al. The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis , 1998, Nature.
[268] M. Schachner,et al. NCAM stimulates the Ras-MAPK pathway and CREB phosphorylation in neuronal cells. , 1999, Journal of neurobiology.