Three isoforms of the Atg16L1 protein contribute different autophagic properties

[1]  齊藤 昌也 Intestinal epithelial cells with impaired autophagy lose their adhesive capacity in the presence of TNF-α , 2013 .

[2]  S. Waguri,et al.  Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity , 2012, Molecular biology of the cell.

[3]  D. Hommes,et al.  Autophagy attenuates the adaptive immune response by destabilizing the immunologic synapse. , 2012, Gastroenterology.

[4]  M. Silverberg,et al.  Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans. , 2012, Gastroenterology.

[5]  Larissa B. Thackray,et al.  Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma , 2012, Cell Host & Microbe.

[6]  Yiping Huang,et al.  Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation , 2012, Cell cycle.

[7]  K. Katsanos,et al.  Role of genetics in the diagnosis and prognosis of Crohn's disease. , 2011, World journal of gastroenterology.

[8]  O. Yokosuka,et al.  Intestinal Epithelial Cells with Impaired Autophagy Lose Their Adhesive Capacity in the Presence of TNF-α , 2011, Digestive Diseases and Sciences.

[9]  R. Xavier,et al.  Autophagy Suppresses Interleukin-1β (IL-1β) Signaling by Activation of p62 Degradation via Lysosomal and Proteasomal Pathways* , 2011, The Journal of Biological Chemistry.

[10]  D. Rubinsztein,et al.  Autophagosome Precursor Maturation Requires Homotypic Fusion , 2011, Cell.

[11]  Ruggeri Rosario Fabio,et al.  ATG16L1 contribution to Crohn's disease risk in Sicily. , 2011, Inflammatory Bowel Diseases.

[12]  M. Oosting,et al.  Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2 , 2011, Gut.

[13]  J. Barrett,et al.  New IBD genetics: common pathways with other diseases , 2011, Gut.

[14]  A. Kaser,et al.  Crohn's disease: NOD2, autophagy and ER stress converge , 2011, Gut.

[15]  D. Rubinsztein,et al.  Plasma membrane contributes to the formation of pre-autophagosomal structures , 2010, Nature Cell Biology.

[16]  D. Philpott,et al.  Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry , 2010, Nature Immunology.

[17]  M. Boulton,et al.  Using LC3 to monitor autophagy flux in the retinal pigment epithelium , 2009, Autophagy.

[18]  F. Inagaki,et al.  Dimeric Coiled-coil Structure of Saccharomyces cerevisiae Atg16 and Its Functional Significance in Autophagy* , 2009, The Journal of Biological Chemistry.

[19]  S. Akira,et al.  Differential Involvement of Atg16L1 in Crohn Disease and Canonical Autophagy , 2009, The Journal of Biological Chemistry.

[20]  Sarah L. Brown,et al.  A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells , 2008, Nature.

[21]  J. Satsangi Faculty Opinions recommendation of Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. , 2008 .

[22]  M. Fukuda,et al.  Direct link between Atg protein and small GTPase Rab: Atg16L functions as a potential Rab33 effector in mammals , 2008, Autophagy.

[23]  A. Yamamoto,et al.  Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation. , 2008, Molecular biology of the cell.

[24]  T. Noda,et al.  The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. , 2008, Molecular biology of the cell.

[25]  Zhong-ying Shen,et al.  Autophagy and endocytosis in the amnion. , 2008, Journal of structural biology.

[26]  T. Ueno,et al.  LC3 and Autophagy. , 2008, Methods in molecular biology.

[27]  Judy H Cho,et al.  Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis , 2007, Nature Genetics.

[28]  Thomas Lengauer,et al.  A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 , 2007, Nature Genetics.

[29]  Long Yu,et al.  Molecular cloning and characterization of rat LC3A and LC3B--two novel markers of autophagosome. , 2006, Biochemical and biophysical research communications.

[30]  A. Tolkovsky,et al.  The Dynamics of Autophagy Visualised in Live Cells: from Autophagosome Formation to Fusion with Endo/lysosomes , 2005, Autophagy.

[31]  C. Ji,et al.  Cloning and Analysis of Human Apg16L , 2004, DNA sequence : the journal of DNA sequencing and mapping.

[32]  T. Natsume,et al.  Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate , 2003, Journal of Cell Science.

[33]  N. Mizushima,et al.  Formation of the ∼350-kDa Apg12-Apg5·Apg16 Multimeric Complex, Mediated by Apg16 Oligomerization, Is Essential for Autophagy in Yeast* , 2002, The Journal of Biological Chemistry.

[34]  N. Mizushima,et al.  Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. , 2002, The Journal of biological chemistry.

[35]  M. Colombo,et al.  A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation. , 2001, Journal of cell science.