CSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages

[1]  F. Fan,et al.  Monocytic Subsets Impact Cerebral Cortex and Cognition: Differences Between Healthy Subjects and Patients With First-Episode Schizophrenia , 2022, Frontiers in Immunology.

[2]  R. Godbout,et al.  Vascular and blood-brain barrier-related changes underlie stress responses and resilience in female mice and depression in human tissue , 2022, Nature Communications.

[3]  A. Zharkovsky,et al.  Sex-Specific Microglial Activation and SARS-CoV-2 Receptor Expression Induced by Chronic Unpredictable Stress , 2021, Frontiers in Cellular Neuroscience.

[4]  Bruce A. Corliss,et al.  Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice , 2021, Nature Communications.

[5]  M. Tremblay,et al.  Microglia contribute to social behavioral adaptation to chronic stress , 2021, Glia.

[6]  G. Locatelli,et al.  Dwellers and Trespassers: Mononuclear Phagocytes at the Borders of the Central Nervous System , 2021, Frontiers in Immunology.

[7]  P. Kochunov,et al.  Allostatic Load Effects on Cortical and Cognitive Deficits in Essentially Normotensive, Normoweight Patients with Schizophrenia. , 2021, Schizophrenia bulletin.

[8]  R. Kahn,et al.  A loss of mature microglial markers without immune activation in schizophrenia , 2021, Glia.

[9]  S. Cronin,et al.  Attenuated CSF‐1R signalling drives cerebrovascular pathology , 2020, EMBO molecular medicine.

[10]  J. Koo,et al.  How Stress Shapes Neuroimmune Function: Implications for the Neurobiology of Psychiatric Disorders , 2020, Biological Psychiatry.

[11]  L. Gan,et al.  A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain , 2020, eLife.

[12]  B. Dean,et al.  Lipid Pathology of the Corpus Callosum in Schizophrenia and the Potential Role of Abnormal Gene Regulatory Networks with Reduced Microglial Marker Expression , 2020, Cerebral cortex.

[13]  Carla Cangalaya,et al.  Light-induced engagement of microglia to focally remodel synapses in the adult brain , 2020, eLife.

[14]  K. Green,et al.  To Kill a Microglia: A Case for CSF1R Inhibitors. , 2020, Trends in immunology.

[15]  A. Riecher-Rössler,et al.  Relation between self-perceived stress, psychopathological symptoms and the stress hormone prolactin in emerging psychosis. , 2020, Journal of psychiatric research.

[16]  Anke Müller,et al.  Long-Term Impact of Early-Life Stress on Hippocampal Plasticity: Spotlight on Astrocytes , 2020, International journal of molecular sciences.

[17]  K. Hashimoto,et al.  Abnormal expression of colony stimulating factor 1 receptor (CSF1R) and transcription factor PU.1 (SPI1) in the spleen from patients with major psychiatric disorders: A role of brain-spleen axis. , 2020, Journal of affective disorders.

[18]  M. Medalla,et al.  Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities , 2020, Molecular Psychiatry.

[19]  Jie Li,et al.  Microglia mediate forgetting via complement-dependent synaptic elimination , 2020, Science.

[20]  Yunlong Tan,et al.  Microglial regional heterogeneity and its role in the brain , 2019, Molecular Psychiatry.

[21]  M. Chakravarty,et al.  Evidence for Network-Based Cortical Thickness Reductions in Schizophrenia. , 2019, The American journal of psychiatry.

[22]  Jeroen A. A. Demmers,et al.  Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia. , 2019, American journal of human genetics.

[23]  Othman Soufan,et al.  NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis , 2019, Nucleic Acids Res..

[24]  I. Ferrer,et al.  Neuroinflammation in the dorsolateral prefrontal cortex in elderly chronic schizophrenia , 2019, European Neuropsychopharmacology.

[25]  B. Zhong,et al.  Reliability and validity of the Chinese version of the Childhood Trauma Questionnaire-Short Form for inpatients with schizophrenia , 2018, PloS one.

[26]  M. Webster,et al.  Increased macrophages and changed brain endothelial cell gene expression in the frontal cortex of people with schizophrenia displaying inflammation , 2018, Molecular Psychiatry.

[27]  J. Pouget,et al.  The Emerging Immunogenetic Architecture of Schizophrenia , 2018, Schizophrenia bulletin.

[28]  N. Santanam,et al.  Cerebrovascular dysfunction with stress and depression , 2018, Brain circulation.

[29]  A. Kaffman,et al.  Early life stress perturbs the function of microglia in the developing rodent brain: New insights and future challenges , 2018, Brain, Behavior, and Immunity.

[30]  J. Trojanowski,et al.  Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy , 2018, Nature Neuroscience.

[31]  S A Small,et al.  Hippocampal dysfunction in the pathophysiology of schizophrenia: a selective review and hypothesis for early detection and intervention , 2018, Molecular Psychiatry.

[32]  R. Duman,et al.  Stress-Induced Neuronal Colony Stimulating Factor 1 Provokes Microglia-Mediated Neuronal Remodeling and Depressive-like Behavior , 2018, Biological Psychiatry.

[33]  N. Williams,et al.  Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia , 2017, Molecular Psychiatry.

[34]  A. Grace,et al.  Adolescent Stress as a Driving Factor for Schizophrenia Development-A Basic Science Perspective. , 2017, Schizophrenia bulletin.

[35]  E. Walker,et al.  The neural diathesis-stress model of schizophrenia revisited: An update on recent findings considering illness stage and neurobiological and methodological complexities , 2017, Neuroscience & Biobehavioral Reviews.

[36]  A. Grace,et al.  Prefrontal Cortex Dysfunction Increases Susceptibility to Schizophrenia-Like Changes Induced by Adolescent Stress Exposure , 2016, Schizophrenia bulletin.

[37]  K. Ji,et al.  Dynamic microglial modulation of spatial learning and social behavior , 2016, Brain, Behavior, and Immunity.

[38]  M. Mehler,et al.  Emerging Roles for CSF-1 Receptor and its Ligands in the Nervous System , 2016, Trends in Neurosciences.

[39]  K. Green,et al.  Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus , 2015, The Journal of Neuroscience.

[40]  C. Branch,et al.  Phenotypic characterization of a Csf1r haploinsufficient mouse model of adult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP) , 2015, Neurobiology of Disease.

[41]  Laura J. Scott,et al.  Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways , 2015, Nature Neuroscience.

[42]  S. Maier,et al.  Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis , 2014, Molecular Psychiatry.

[43]  M. Bar,et al.  The role of the parahippocampal cortex in cognition , 2013, Trends in Cognitive Sciences.

[44]  I. Mansuy,et al.  Neural Mechanisms of Stress Resilience and Vulnerability , 2012, Neuron.

[45]  Bruce Fischl,et al.  FreeSurfer , 2012, NeuroImage.

[46]  A. Achim,et al.  How prevalent are anxiety disorders in schizophrenia? A meta-analysis and critical review on a significant association. , 2011, Schizophrenia bulletin.

[47]  M. Pruessner,et al.  Stress and protective factors in individuals at ultra-high risk for psychosis, first episode psychosis and healthy controls , 2011, Schizophrenia Research.

[48]  T. Lam,et al.  Three versions of Perceived Stress Scale: validation in a sample of Chinese cardiac patients who smoke , 2010, BMC public health.

[49]  Edward T Bullmore,et al.  Morphometric brain abnormalities in schizophrenia in a population-based sample: relationship to duration of illness. , 2010, Schizophrenia bulletin.

[50]  P. Fitzgerald,et al.  Superior temporal gyrus volume change in schizophrenia: A review on Region of Interest volumetric studies , 2009, Brain Research Reviews.

[51]  M. Newcomb,et al.  Development and validation of a brief screening version of the Childhood Trauma Questionnaire. , 2003, Child abuse & neglect.

[52]  David M. Diamond,et al.  The stressed hippocampus, synaptic plasticity and lost memories , 2002, Nature Reviews Neuroscience.

[53]  A. Dale,et al.  Whole Brain Segmentation Automated Labeling of Neuroanatomical Structures in the Human Brain , 2002, Neuron.

[54]  T. Kamarck,et al.  A global measure of perceived stress. , 1983, Journal of health and social behavior.

[55]  S. Dursun,et al.  An Overview of Animal Models Related to Schizophrenia , 2019, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[56]  P. McGuire,et al.  The blood-brain barrier in psychosis. , 2018, The lancet. Psychiatry.

[57]  S. Rasool,et al.  Schizophrenia: An overview , 2018 .

[58]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[59]  R. Russell,et al.  Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects. , 2002, Blood.