Ascorbic acid and copper in linoleate oxidation--Dunkley revisited.

AbstractThe observation that reduced metals are more effective than the corresponding oxidised species in inducing peroxidation of linoleate underpins much of the study of metal-mediated lipid peroxidation which has taken place over the last 30 years. The four papers from the laboratory of WL Dunkley reviewed herein follow the observations of Ray et al.1 that the degradation of isolated serum lipoproteins was oxidative in nature and metal-ion-dependent.