GlyTouCan: an accessible glycan structure repository.

Rapid and continued growth in the generation of glycomic data has revealed the need for enhanced development of basic infrastructure for presenting and interpreting these datasets in a manner that engages the broader biomedical research community. Early in their growth, the genomic and proteomic fields implemented mechanisms for assigning unique gene and protein identifiers that were essential for organizing data presentation and for enhancing bioinformatic approaches to extracting knowledge. Similar unique identifiers are currently absent from glycomic data. In order to facilitate continued growth and expanded accessibility of glycomic data, the authors strongly encourage the glycomics community to coordinate the submission of their glycan structures to the GlyTouCan Repository and to make use of GlyTouCan identifiers in their communications and publications. The authors also deeply encourage journals to recommend a submission workflow in which submitted publications utilize GlyTouCan identifiers as a standard reference for explicitly describing glycan structures cited in manuscripts.

[1]  Kiyoko F. Aoki-Kinoshita,et al.  KEGG as a glycome informatics resource. , 2006, Glycobiology.

[2]  K Bock,et al.  The Complex Carbohydrate Structure Database. , 1989, Trends in biochemical sciences.

[3]  Matthew P. Campbell,et al.  UniCarbKB: New database features for integrating glycan structure abundance, compositional glycoproteomics data, and disease associations. , 2016, Biochimica et biophysica acta.

[4]  Evan Bolton,et al.  Symbol Nomenclature for Graphical Representations of Glycans. , 2015, Glycobiology.

[5]  P. Albersheim,et al.  Letter to the Glyco-Forum CarbBank , 1992 .

[6]  Erdmann Rapp,et al.  MIRAGE: The minimum information required for a glycomics experiment , 2014, Glycobiology.

[7]  Philip V. Toukach,et al.  Carbohydrate structure database merged from bacterial, archaeal, plant and fungal parts , 2015, Nucleic Acids Res..

[8]  Lennart Martens,et al.  The minimum information about a proteomics experiment (MIAPE) , 2007, Nature Biotechnology.

[9]  Niclas G. Karlsson,et al.  SugarBindDB, a resource of glycan-mediated host–pathogen interactions , 2015, Nucleic Acids Res..

[10]  Catherine A. Hayes,et al.  UniCarb-DB: a database resource for glycomic discovery , 2011, Bioinform..

[11]  Thomas Wetter,et al.  GlycomeDB – integration of open-access carbohydrate structure databases , 2008, BMC Bioinformatics.

[12]  Kiyoko F. Aoki-Kinoshita,et al.  Implementation of GlycanBuilder to draw a wide variety of ambiguous glycans. , 2017, Carbohydrate research.

[13]  Kiyoko F. Aoki-Kinoshita,et al.  GlyTouCan 1.0 – The international glycan structure repository , 2015, Nucleic Acids Res..

[14]  Jason E. Stewart,et al.  Minimum information about a microarray experiment (MIAME)—toward standards for microarray data , 2001, Nature Genetics.

[15]  Erdmann Rapp,et al.  The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets. , 2016, Glycobiology.

[16]  Kiyoko F. Aoki-Kinoshita A Practical Guide to Using Glycomics Databases , 2017 .

[17]  Erdmann Rapp,et al.  The Minimum Information Required for a Glycomics Experiment (MIRAGE) Project: Improving the Standards for Reporting Mass-spectrometry-based Glycoanalytic Data , 2013, Molecular & Cellular Proteomics.

[18]  Erdmann Rapp,et al.  The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data , 2016, Glycobiology.

[19]  Wei Lang,et al.  Advancing glycomics: implementation strategies at the consortium for functional glycomics. , 2006, Glycobiology.

[20]  Philip V. Toukach,et al.  Sharing of worldwide distributed carbohydrate-related digital resources: online connection of the Bacterial Carbohydrate Structure DataBase and GLYCOSCIENCES.de , 2007, Nucleic Acids Res..

[21]  Xianyu Li,et al.  The Fifth ACGG-DB Meeting report : towards an international glycan structure repository , 2013 .