M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

[1]  Chao Zhao,et al.  Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination. , 2013, Brain : a journal of neurology.

[2]  K. Nakao,et al.  Secreted protein lipocalin‐2 promotes microglial M1 polarization , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[3]  S. Appel,et al.  Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS , 2012, Experimental Neurology.

[4]  M. Hedger,et al.  The roles of activin A and its binding protein, follistatin, in inflammation and tissue repair , 2012, Molecular and Cellular Endocrinology.

[5]  C. Moon,et al.  Immunohistochemical study of arginase-1 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis , 2012, Brain Research.

[6]  A. Ishii,et al.  Erk1/2 MAPK and mTOR signaling sequentially regulates progression through distinct stages of oligodendrocyte differentiation , 2012, Glia.

[7]  M. Olah,et al.  Identification of a microglia phenotype supportive of remyelination , 2012, Glia.

[8]  Yan Xu,et al.  Stem Cells Decreased Neuronal Cell Death after Hypoxic Stress in Primary Fetal Rat Neurons in Vitro 1 , 2012, Cell transplantation.

[9]  C. Trebst,et al.  Characterisation of microglia during de- and remyelination: Can they create a repair promoting environment? , 2012, Neurobiology of Disease.

[10]  R. Franklin,et al.  Rejuvenation of regeneration in the aging central nervous system. , 2012, Cell stem cell.

[11]  Hong Yang,et al.  Neuroprotective Effects of Exogenous Activin A on Oxygen-Glucose Deprivation in PC12 Cells , 2011, Molecules.

[12]  J. Davies,et al.  Mesenchymal stromal cells mediate a switch to alternatively activated monocytes/macrophages after acute myocardial infarction , 2011, Basic Research in Cardiology.

[13]  F. Rossi,et al.  Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool , 2011, Nature Neuroscience.

[14]  E. Huang,et al.  Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination , 2011, Nature Neuroscience.

[15]  M. Biran,et al.  Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration , 2011, Multiple sclerosis.

[16]  P. Chambon,et al.  Retinoid X receptor gamma signaling accelerates CNS remyelination , 2011, Nature Neuroscience.

[17]  R. Ransohoff,et al.  Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice , 2010, PloS one.

[18]  V. Gallo,et al.  Adult-born SVZ progenitors receive transient glutamatergic synapses during remyelination of the corpus callosum , 2010, Nature Neuroscience.

[19]  P. Sawchenko,et al.  Dual Roles for Perivascular Macrophages in Immune-to-Brain Signaling , 2010, Neuron.

[20]  Jessica K. Alexander,et al.  Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord , 2009, The Journal of Neuroscience.

[21]  N. Rosenthal,et al.  A CREB-C/EBPβ cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair , 2009, Proceedings of the National Academy of Sciences.

[22]  C. Sommerer,et al.  Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats. , 2009, American journal of physiology. Renal physiology.

[23]  D. Kirschner,et al.  Constitutively Active Akt Induces Enhanced Myelination in the CNS , 2008, The Journal of Neuroscience.

[24]  C. Wegner,et al.  Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis. , 2008, Brain : a journal of neurology.

[25]  S. Youssef,et al.  Type II monocytes modulate T cell–mediated central nervous system autoimmune disease , 2007, Nature Medicine.

[26]  A. Abdel-Zaher,et al.  Role of nitric oxide and reduced glutathione in the protective effects of aminoguanidine, gadolinium chloride and oleanolic acid against acetaminophen-induced hepatic and renal damage. , 2007, Toxicology.

[27]  F. Marincola,et al.  Gene expression profiling of cutaneous wound healing , 2007, Journal of Translational Medicine.

[28]  Xia Zhang,et al.  Biochemical and functional characterization of three activated macrophage populations , 2006, Journal of leukocyte biology.

[29]  K. Nave,et al.  Cdc42 and Rac1 Signaling Are Both Required for and Act Synergistically in the Correct Formation of Myelin Sheaths in the CNS , 2006, The Journal of Neuroscience.

[30]  Chao Zhao,et al.  Myelin Impairs CNS Remyelination by Inhibiting Oligodendrocyte Precursor Cell Differentiation , 2006, The Journal of Neuroscience.

[31]  Chao Zhao,et al.  Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression , 2005, Neurobiology of Disease.

[32]  D. Rowitch,et al.  bHLH Transcription Factor Olig1 Is Required to Repair Demyelinated Lesions in the CNS , 2004, Science.

[33]  M. Resh,et al.  Signaling from Integrins to Fyn to Rho Family GTPases Regulates Morphologic Differentiation of Oligodendrocytes , 2004, The Journal of Neuroscience.

[34]  N. Rooijen,et al.  Microglia Promote the Death of Developing Purkinje Cells , 2004, Neuron.

[35]  M. Cuzner,et al.  Role for TGF‐β1, FGF‐2 and PDGF‐AA in a myelination of CNS aggregate cultures enriched with macrophages , 2003, Journal of neuroscience research.

[36]  Prabir Ray,et al.  A critical role for NF-κB in Gata3 expression and TH2 differentiation in allergic airway inflammation , 2001, Nature Immunology.

[37]  Hua,et al.  Identification of , 2000, Journal of insect physiology.

[38]  L. Decker,et al.  Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination , 1999, The European journal of neuroscience.

[39]  Woodruff,et al.  The expression of myelin protein mRNAs during remyelination of lysolecithin‐induced demyelination , 1999, Neuropathology and applied neurobiology.

[40]  J. Goldman,et al.  Endogenous Progenitors Remyelinate Demyelinated Axons in the Adult CNS , 1997, Neuron.

[41]  J. Massagué,et al.  Activation of signalling by the activin receptor complex , 1996, Molecular and cellular biology.

[42]  J. Brain,et al.  Gadolinium induces macrophage apoptosis , 1996, Journal of leukocyte biology.

[43]  D. Laskin,et al.  Inhibition of macrophages with gadolinium chloride abrogates ozone-induced pulmonary injury and inflammatory mediator production. , 1995, American journal of respiratory cell and molecular biology.

[44]  M. Matzuk Functional analysis of mammalian members of the transforming growth factor-β superfamily , 1995, Trends in Endocrinology & Metabolism.

[45]  A. Bradley,et al.  Different phenotypes for mice deficient in either activins or activin receptor type II , 1995, Nature.

[46]  G. Piras,et al.  A role for TGF-beta in oligodendrocyte differentiation , 1993, The Journal of cell biology.

[47]  Y. Zhang,et al.  Microglia present myelin antigens to T cells after phagocytosis of oligodendrocytes. , 1993, Cellular immunology.

[48]  G. Kreutzberg,et al.  Cytotoxicity of microglia , 1992, Journal of Neuroimmunology.

[49]  C. Hulstaert,et al.  Heterogeneity of rat liver and spleen macrophages in gadolinium chloride–induced elimination and repopulation , 1992, Journal of leukocyte biology.