Hand‐assisted laparoscopic donor nephrectomy for pediatric kidney allograft recipients

Abstract:  Laparoscopic donor nephrectomy (LDN) is the method of choice for procuring kidneys from living donors at many transplant centers. The aim of this study was to assess the feasibility as well as outcome of LDN in pediatric recipients. Twenty‐two pediatric patients, 18‐yr old or younger received kidneys procured by a hand‐assisted LDN technique. The mean operative time was no different (p = 0.9) and the mean length of stay was more than 1 day shorter in the LDN group (p = 0.0001) compared with the 13 pediatric patients who received kidneys by standard open nephrectomy. Body mass index (BMI), number of donor kidney vessels, or laterality of the kidney did not impact the donor operation or outcome. Actuarial 1‐yr patient survival was 100% and allograft survival was 95%, which are equivalent to registry data. There were no donor mortalities and there were five morbidities. None required hospitalization. There were no conversions from LDN to open nephrectomy. One kidney was lost because of overwhelming infection necessitating withdrawal of immunosuppression. In conclusion, hand‐assisted LDN is a safe method of procuring kidneys from potential donors with no significant negative outcomes to the pediatric recipients.

[1]  L. Kavoussi,et al.  Laparoscopic adult donor nephrectomy for pediatric renal transplantation. , 2003, Urology.

[2]  B. Wolfe,et al.  Early and late recipient graft function and donor outcome after laparoscopic vs open adult live donor nephrectomy for pediatric renal transplantation. , 2002, Archives of surgery.

[3]  M. Stegall,et al.  Hand-assisted laparoscopic donor nephrectomy for morbidly obese patients. , 2002, Transplantation proceedings.

[4]  L. Kavoussi,et al.  Laparoscopic live donor nephrectomy. A review of the first 5 years. , 2001, The Urologic clinics of North America.

[5]  P. Acott,et al.  Extravesical ureteroneocystostomy with and without internalized ureteric stents in pediatric renal transplantation , 2001, Pediatric transplantation.

[6]  A. Farney,et al.  Increased Rates of Donation With Laparoscopic Donor Nephrectomy , 2000, Annals of surgery.

[7]  L. Kavoussi,et al.  Complications of laparoscopic live donor nephrectomy: the first 175 cases. , 2000, Transplantation proceedings.

[8]  J. Wolf,et al.  Prospective, case matched comparison of hand assisted laparoscopic and open surgical live donor nephrectomy. , 2000, The Journal of urology.

[9]  R. Rege,et al.  LAPAROSCOPIC LIVE DONOR NEPHRECTOMY—IS IT SAFE?: Analysis of 80 Consecutive Cases and Comparison with Open Nephrectomy , 1999 .

[10]  W. Rosenberger,et al.  Comparison of open and laparoscopic live donor nephrectomy. , 1997, Annals of surgery.

[11]  C. Olsson,et al.  Renal effects of CO2 insufflation: oliguria and acute renal dysfunction in a rat pneumoperitoneum model. , 1994, Urology.

[12]  N Bilgin,et al.  Living unrelated donor kidney transplantation. , 1992, Transplantation Proceedings.

[13]  I. Kron,et al.  Elevated Intra‐abdominal Pressure and Renal Function , 1982, Annals of surgery.

[14]  J. Cecka The UNOS Renal Transplant Registry. , 2002, Clinical transplants.

[15]  R. Rege,et al.  Laparoscopic live donor nephrectomy--is it safe? , 2000, Transplantation.