expression of hereditary hemochromatosis promoter polymorphisms influence the phenotypic α Tumor necrosis factor

[1]  J. Steer,et al.  Effects of stimulus and cell type on the expression of the -308 tumour necrosis factor promoter polymorphism. , 2000, Cytokine.

[2]  M. Linder,et al.  Secretion of Ferritin by Rat Hepatoma Cells and Its Regulation by Inflammatory Cytokines and Iron , 1997 .

[3]  Schneider,et al.  A tumour necrosis factor‐alpha (TNF‐α) promoter polymorphism is associated with chronic hepatitis B infection , 1998 .

[4]  L. Powell,et al.  Haemochromatosis in the new millennium. , 2000, Journal of hepatology.

[5]  D. Banerjee,et al.  Ferritin release by mononuclear cells in hereditary hemochromatosis. , 1989, The Journal of laboratory and clinical medicine.

[6]  D. Conte,et al.  Response of monocyte iron regulatory protein activity to inflammation: abnormal behavior in genetic hemochromatosis. , 1998, Blood.

[7]  D. Kwiatkowski,et al.  Association of a Tumour Necrosis Factor Promoter Polymorphism with Susceptibility to Pulmonary Tuberculosis , 1996 .

[8]  D. Girelli,et al.  Heterogeneity of hemochromatosis in Italy. , 1998, Gastroenterology.

[9]  A. Blakemore,et al.  Single base polymorphism in the human tumour necrosis factor alpha (TNF alpha) gene detectable by NcoI restriction of PCR product. , 1992, Human molecular genetics.

[10]  D. Girelli,et al.  The ancestral hemochromatosis haplotype is associated with a severe phenotype expression in Italian patients , 1996, Hepatology.

[11]  M. Manns,et al.  The tumor necrosis factor-α promoter correlates with progression of primary biliary cirrhosis , 1999 .

[12]  M. J. Page,et al.  γδ intraepithelial lymphocytes drive tumor necrosis factor‐α responsiveness to intestinal iron challenge: relevance to hemochromatosis , 1999 .

[13]  F. Torti,et al.  Tumor necrosis factor-alpha and interleukin 1-alpha regulate transferrin receptor in human diploid fibroblasts. Relationship to the induction of ferritin heavy chain. , 1991, The Journal of biological chemistry.

[14]  J. Grove,et al.  Association of a tumor necrosis factor promoter polymorphism with susceptibility to alcoholic steatohepatitis , 1997, Hepatology.

[15]  G. Gerken,et al.  Tumor necrosis factor alpha promoter polymorphism at position ‐238 is associated with chronic active hepatitis C infection , 1998, Journal of medical virology.

[16]  P. Donaldson,et al.  Tumor necrosis factor genomic polymorphism and outcome of acetaminophen (paracetamol)-induced acute liver failure. , 1998, Journal of hepatology.

[17]  L. Abraham,et al.  The −308 tumor necrosis factor-α promoter polymorphism effects transcription , 1997 .

[18]  F. Pociot,et al.  Functional Analysis of a New Polymorphism in the Human TNF α Gene Promoter , 1995, Scandinavian journal of immunology.

[19]  H. Mcdevitt,et al.  Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[20]  K. Taylor,et al.  Donor polymorphism of tumor necrosis factor gene: relationship with variable severity of hepatitis C recurrence after liver transplantation. , 1999, Transplantation.

[21]  L. N. Valenti,et al.  Relationship between TNF‐α and iron metabolism in differentiating human monocytic THP‐1 cells , 2000 .

[22]  L. Moldawer,et al.  Cachectin/tumor necrosis factor‐α alters red blood cell kinetics and induces anemia in vivo , 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[23]  P. Galle,et al.  Different Transcriptional Activity and In Vitro TNF-α Production in Psoriasis Patients Carrying the TNF-α 238A Promoter Polymorphism , 2000 .

[24]  F. Torti,et al.  Iron-independent induction of ferritin H chain by tumor necrosis factor. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[25]  Y. Kohgo,et al.  Regulation of iron metabolism in HepG2 cells: A possible role for cytokines in the hepatic deposition of iron , 1993, Hepatology.

[26]  D. Conte,et al.  Inappropriately high iron regulatory protein activity in monocytes of patients with genetic hemochromatosis. , 1997, Blood.

[27]  S. Young,et al.  Modulation of iron metabolism in monocyte cell line U937 by inflammatory cytokines: changes in transferrin uptake, iron handling and ferritin mRNA. , 1993, The Biochemical journal.

[28]  K. Myambo,et al.  The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor-inducible gene. , 1988, The Journal of biological chemistry.

[29]  P. Donaldson,et al.  Frequency and nature of cytokine gene polymorphisms in type 1 autoimmune hepatitis , 1999, Hepatology.

[30]  M. C. Ellis,et al.  A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis , 1996, Nature Genetics.

[31]  J. Newton,et al.  Tumour necrosis factor-a promoter polymorphisms in primary biliary cirrhosis , 1999 .

[32]  M. Colombo,et al.  Wild-type HFE protein normalizes transferrin iron accumulation in macrophages from subjects with hereditary hemochromatosis. , 2000, Blood.

[33]  J. Olynyk,et al.  A population-based study of the clinical expression of the hemochromatosis gene. , 1999, The New England journal of medicine.

[34]  N. Hayashi,et al.  Delayed fas‐mediated hepatocyte apoptosis during liver regeneration in mice: hepatoprotective role of TNFα , 1998, Hepatology.

[35]  P. Brissot.  The discovery of the new haemochromatosis gene , 2003 .

[36]  A. R. Muir,et al.  Hepatic pathology in relatives of patients with haemochromatosis. , 1962, The Journal of pathology and bacteriology.

[37]  S. Sherlock,et al.  Measurement of liver-iron concentration in needle-biopsy specimens. , 1971, Lancet.

[38]  S. D'alfonso,et al.  A polymorphic variation in a putative regulation box of the TNFA promoter region , 2004, Immunogenetics.

[39]  J. Brock,et al.  Induction of hypoferremia and modulation of macrophage iron metabolism by tumor necrosis factor. , 1989, Laboratory investigation; a journal of technical methods and pathology.