Sinusoidal obstruction syndrome associated with the ingestion of gynura root

absorption would have made the half-life appear longer. Thus, our patient’s true elimination half-life was probably shorter. As the writers pointed out, using this shorter half-life in the equation would yield a larger total body clearance value. This would bolster the argument that CVVH had a smaller impact on the total clearance of acetaminophen. We did not mean to suggest that we endorse CVVH as a preferred procedure for extracorporeal removal of acetaminophen. It may help remove some of the ingested drug, and assist in restoration of a normal blood pH. However, if rapid removal of large amounts of acetaminophen is necessary, conventional high-flux, high-flow hemodialysis would be superior.